Impaired inducibility of xenobiotic and antioxidant responses in rainbow trout exposed to polychlorinated biphenyl contaminated sediments in the St. Lawrence River

The biological half-life [Formula: see text] of 31 dichloro- to decachloro-biphenyl congeners were monitored for 105 d in adult rainbow trout (Salmo gairdneri) that were exposed to a single oral dose. In whole fish [Formula: see text] increased from 5 d to no apparent elimination as the number of chlorines on the biphenyl increased. This structure–activity relationship was not as evident in muscle where [Formula: see text] ranged from < 5 to 127 d. We suggest the decline in muscle resulted from decreasing lipid levels and the redistribution of congeners within the fish. From structure–activity analysis of [Formula: see text] in whole fish we conclude that elimination is enhanced for those congeners with lower chlorine content, with no chlorine substitutions in the ortho positions, and those with two unsubstituted carbons that are adjacent (vicinal) on the biphenyl. A significant decline in total PCB content in whole fish, equivalent to a [Formula: see text] of 219 d, was partly due to the composition of the PCB mixture administered, and the selective elimination of the lower chlorinated biphenyls.

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Effects of rearing density and dietary tryptophan supplementation on intestinal immune and antioxidant responses in rainbow trout (Oncorhynchus mykiss)

Aquaculture ◽

10.1016/j.aquaculture.2020.735537 ◽

2020 ◽

Vol 528 ◽

pp. 735537

Author(s):

Seyyed Morteza Hoseini ◽

Morteza Yousefi ◽

Ali Taheri Mirghaed ◽

Bilal Ahamad Paray ◽

Seyed Hossein Hoseinifar ◽

...

Keyword(s):

Rainbow Trout ◽

Oncorhynchus Mykiss ◽

Antioxidant Responses ◽

Rainbow Trout Oncorhynchus Mykiss ◽

Rearing Density

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Antioxidant responses and plasma biochemical characteristics in the freshwater rainbow trout, Oncorhynchus mykiss, after acute exposure to the fungicide propiconazole

Czech Journal of Animal Science ◽

10.17221/35/2010-cjas ◽

2011 ◽

Vol 56 (No. 2) ◽

pp. 61-69 ◽

Cited By ~ 20

Author(s):

Z.-H. Li ◽

V. Zlabek ◽

J. Velíšek ◽

R. Grabic ◽

J. Machová ◽

...

Keyword(s):

Oxidative Stress ◽

Rainbow Trout ◽

Oncorhynchus Mykiss ◽

Control Group ◽

Antioxidant Responses ◽

Stress Indices ◽

Rainbow Trout Oncorhynchus Mykiss ◽

Plasma Enzymes ◽

Plasma Characteristics ◽

The Brain

In this study, the toxic effects of PCZ, a triazole fungicide present in aquatic environment, were studied in rainbow trout, Oncorhynchus mykiss, by an acute toxicity test. Compared to the control group, fish exposed to PCZ (96-h-LC50, 5.04 mg/l) showed significantly higher (P < 0.05) plasma NH3 and GLU concentration and the activities of plasma enzymes including CK, ALT, AST, LDH, but the TP content was not significantly different (P > 0.05). The oxidative stress indices (levels of LPO and CP) of brain and muscle in the experimental group were higher compared to the control group, especially for a significant change (P < 0.05) in the brain. SOD, CAT, GPx and GR activity in the brain of experimental groups was significantly lower (P < 0.05), however, an opposite tendency was found out in muscle. In addition, there are significant correlations between TBARS and CAT, TBARS and GPx, CP, and CAT, GR, and GPx in the fish brain. Thus, PCZ exposure changed the oxidative stress indices and plasma characteristics, and these changes may be used as potential bioindicators of the exposure and effect of PCZ in the controlled experiment. The use in monitoring of PCZ exposure under natural field conditions is possible, but it needs further investigations.

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Defining the sources of airborne polychlorinated biphenyls: evidence for the influence of microbially dechlorinated congeners from river sediment?

Canadian Journal of Fisheries and Aquatic Sciences ◽

10.1139/f99-240 ◽

2000 ◽

Vol 57 (S1) ◽

pp. 86-94 ◽

Cited By ~ 14

Author(s):

Jeff Chiarenzelli ◽

Brian Bush ◽

Ann Casey ◽

Ed Barnard ◽

Bob Smith ◽

...

Keyword(s):

Great Lakes ◽

River Sediment ◽

Polychlorinated Biphenyl ◽

Specific Pattern ◽

Great Lakes Region ◽

Superfund Sites ◽

Aroclor 1248 ◽

Time Period ◽

A Minor ◽

St Lawrence River

Sampling on Akwesasne Mohawk Nation lands during 1993 yielded elevated polychlorinated biphenyl (PCB) concentrations comparable with those of other areas impacted by the discharge of PCBs. The summer air PCB congener- specific pattern in proximity to three Superfund sites along the St. Lawrence River suggests that the volatilization of Aroclor 1248, used extensively at all three downwind sites, is the dominant source. A dechlorinated source, presumably from river sediment and waters, is a minor contributor (~12%) to the pattern. These two sources can account for ~80% of the observed pattern. At a small cove adjacent to an industrial landfill, summer concentrations exceeded those measured in the winter by a factor of 27. At all sample sites during the summer months (June-August), concentrations and chlorine to biphenyl ratios increased, and similar congener-specific PCB patterns were observed. During the colder months, PCB concentrations at all sites decreased but were elevated with respect to those measured elsewhere in the Great Lakes region during the same time period.

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