Prophylactic antibiotics after abortion Darj E, Stralin E. Nilsson S: The Prophylactic Effect of Doxycycline on Postoperative Infection Rate After First-Trimester Abortion. 70(5):755–758, 1987

1988 ◽  
Vol 33 (3) ◽  
pp. 144
1982 ◽  
Vol 3 (1) ◽  
pp. 34-37 ◽  
Author(s):  
Ronald Lee Nichols

AbstractThe most important factors in controlling postsurgical sepsis are appropriate surgical judgment and technique. Efficacious prophylactic antibiotics, when indicated, also significantly reduce the postoperative infection rate. Among the other techniques often heralded as important adjunctive measures, only duration of preoperative hospitalization, preoperative bathing, use of electrocautery, preoperative hair removal, use of prophylactic drains, and duration of operation are of proven significance.


Author(s):  
Ida Kotisalmi ◽  
Maija Hytönen ◽  
Antti A. Mäkitie ◽  
Markus Lilja

Abstract Purpose One of the most common complications after septoplasty is a postoperative infection. We investigated the number of postoperative infections and unplanned postoperative visits (UPV) in septoplasties with and without additional nasal surgery at our institution and evaluated the role of antibiotic prophylaxis. Methods We collected data of all consecutive 302 septoplasty or septocolumelloplasty patients operated during the year 2018 at the Department of Otorhinolaryngology-Head and Neck Surgery, HUS Helsinki University Hospital (Helsinki, Finland). Hospital charts were reviewed to record sociodemographic patient characteristics and clinical parameters regarding surgery and follow-up. Results Altogether 239 patients (79.1%) received pre- and/or postoperative prophylactic antibiotics and within this group 3.3% developed a postoperative infection. The infection rate in the non-prophylaxis group of 63 patients was 12.7% (p = 0.007). When all patients who received postoperative antibiotics were excluded, we found that the infection rate in the preoperative prophylaxis group was 3.8%, as opposed to an infection rate of 12.7% in the non-prophylaxis group (p = 0.013). When evaluating septoplasty with additional sinonasal surgery (n = 115) the rate of postoperative infection was 3.3% in the prophylaxis group and 16.7% in the non-prophylaxis group (p = 0.034). These results show a statistically significant stand-alone effect of preoperative prophylactic antibiotics in preventing postoperative infection in septoplasty, especially regarding additional sinonasal surgery. Conclusion The use of preoperative antibiotics as a prophylactic measure diminished statistically significantly the rate of infections and UPVs in septoplasty when all postoperative infections, superficial and mild ones included, were taken into account.


2017 ◽  
Vol 1 (7) ◽  
pp. e034 ◽  
Author(s):  
Ashley J. Tisosky ◽  
Otatade Iyoha-Bello ◽  
Nicholas Demosthenes ◽  
Giovanni Quimbayo ◽  
Tara Coreanu ◽  
...  

2017 ◽  
Vol 17 (9) ◽  
pp. 1209-1214 ◽  
Author(s):  
Jonathan G. Seavey ◽  
George C. Balazs ◽  
Theodore Steelman ◽  
Melvin Helgeson ◽  
David E. Gwinn ◽  
...  

1995 ◽  
Vol 3 (3) ◽  
pp. 102-109 ◽  
Author(s):  
Jens-Jörgen Platz-Christensen ◽  
Carl Påhlson ◽  
Per-Göran Larsson

Objective:The production of hydrogen peroxide(H2O2)from different strains of lactobacilli in the vagina has been proposed to play one of the most important protective roles in the vaginal defense system. New data have, however, suggested that Döderlein's bacteria, with the morphological appearance of long lactobacilli, have a low production ofH2O2. The purpose of the present study was to correlate the morphology of lactobacilli with the incidence of infection following legal abortion.Methods:Seven hundred sixty-nine women with lactobacilli but withoutChlamydia trachomatisor bacterial vaginosis in their vaginal wet smears who were to undergo legal abortions were divided into 6 different groups according to the morphological appearance of the lactobacilli. The postoperative infection rates in these different groups were compared. A phenotypic classification of some of the lactobacilli was performed.Results:The presence of Döderlein's bacteria compared with a mixed flora of lactobacilli increased the risk of postoperative infection 3 times [relative risk (RR) = 3.0; 95% confidence interval (CI), 1.5-6.3]. After a logistic regression analysis, the only independent risk factors were the presence of Döderlein's bacteria and earlier gestational age.Conclusions:We found that the lactobacilli regarded as commensal organisms and “normal, healthy lactobacilli” in the vagina were present in only 18% of these women and that their presence might be hazardous. Therefore, we must reconsider our concept of the “normal” lactobacilli in the vaginal wet smears of healthy women.


2011 ◽  
Vol 36 (6) ◽  
pp. 1155-1161 ◽  
Author(s):  
David J. Biau ◽  
Philippe Leclerc ◽  
Simon Marmor ◽  
Valerie Zeller ◽  
Wilfrid Graff ◽  
...  

Author(s):  
Chilan B.G. Leite ◽  
João M.N. Montechi ◽  
Gilberto L. Camanho ◽  
Riccardo G. Gobbi ◽  
Fabio J. Angelini

AbstractPostoperative infections after allograft implantation is a major concern in knee ligament reconstructions considering the theoretical risk of disease transmission and its potential severity. Here, we aimed to evaluate the postoperative infection rate after knee ligament reconstructions using aseptically processed allografts, and provide an overview of the allografts use in an academic tertiary hospital. A retrospective study was performed evaluating patients who underwent knee ligament reconstructions using aseptically processed allografts, including primary and revision surgeries, from 2005 to 2018. Demographic data, including the type of knee injury and trauma energy, and postoperative data were collected focusing on postoperative infections. Regarding these infected cases, further analyses were performed considering the presenting signs and symptoms, the isolated microorganism identified in culture, the time between graft implantation and diagnosis of infection (defined as acute, subacute, and late), and the need for graft removal. A total of 180 cases of ligament reconstructions were included. The mean follow-up was 8.2 (range: 2.1–15.6) years and the mean age at surgery was 34.1 (± 11.1) years. A total of 262 allografts were implanted in those 180 cases, 93 (35.5%) as bone plug allografts and 169 (64.5%) as soft tissue allografts. Common surgical indications included multiligament reconstruction (57.2%) and primary anterior cruciate ligament (ACL) reconstruction (15%). Seven cases (3.9%) presented postoperative infections. Knee pain (100%) and swelling (100%) were the most prevalent symptoms. Two cases (28.6%) presented sinus tract. Allografts were removed in two cases, the same cases that presented draining sinus (p = 0.04). High-energy trauma was the only statistically associated factor for infection (p = 0.04). No significant association between infection and the type of allograft (p > 0.99) or sex (p = 0.35) were observed. Four cases (57.1%) had monomicrobial staphylococcal infections. Based on that, the allograft-related infection rate was 1.7% (the remaining three infected cases). Nonirradiated, aseptically processed allografts have a low postoperative infection rate in knee ligament reconstructions, being a safe alternative for surgeries that require additional source, increased variety, and quantity of grafts.


1996 ◽  
Vol 63 (2) ◽  
pp. 457-459 ◽  
Author(s):  
Josep M. Badia ◽  
Josep M. Torres ◽  
Cristina Tur ◽  
Antonio Sitges-Serra

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