Developmental study of factors controlling microtubule in vitro cold-stability in rat cerebrum

1988 ◽  
Vol 42 (2) ◽  
pp. 199-204 ◽  
Author(s):  
Catherine Faivre-Sarrailh ◽  
Alain Rabié
Keyword(s):  
Developmental Study ◽  
Cold Stability ◽  
Rat Cerebrum

Safety Assessment of a Hydroethanolic Extract of Caralluma fimbriata

2013 ◽  
Vol 32 (5) ◽  
pp. 385-394 ◽  
Author(s):  
Antoinette Y. Odendaal ◽  
Narendra S. Deshmukh ◽  
Tennille K. Marx ◽  
Alexander G. Schauss ◽  
John R. Endres ◽  
...  
Keyword(s):  
Developmental Toxicity ◽  
Toxicity Study ◽  
Developmental Study ◽  
Sprague Dawley ◽  
Oral Toxicity ◽  
Toxicological Assessment ◽  
Sprague Dawley Rats ◽  
Chromosomal Aberration Test ◽  
Hydroethanolic Extract

This toxicological assessment evaluated the safety of a hydroethanolic extract prepared from Caralluma fimbriata (CFE), a dietary supplement marketed worldwide as an appetite suppressant. Studies included 2 in vitro genotoxicity assays, a repeated dose oral toxicity study, and a developmental study in rats. No evidence of in vitro mutagenicity or clastogenicity surfaced in the in vitro studies at concentrations up to 5000 μg of extract/plate (Ames test) or 5000 μg of extract/mL (chromosomal aberration test). No deaths or treatment-related toxicity were seen in the 6-month chronic oral toxicity study in Sprague-Dawley rats conducted at 3 doses (100, 300, and 1000 mg/kg body weight (bw)/d). The no observed effect level for CFE in this study was considered to be 1000 mg/kg bw/d. A prenatal developmental toxicity study conducted at 3 doses (250, 500, and 1000 mg/kg bw/d) in female Sprague-Dawley rats resulted in no treatment-related external, visceral, or skeletal fetal abnormalities, and no treatment-related maternal or pregnancy alterations were seen at and up to the maximum dose tested. CFE was not associated with any toxicity or adverse events.

In vitro characterization of Mato's FGP cells isolated from rat cerebrum

2002 ◽  
Vol 317 (3) ◽  
pp. 127-130 ◽  
Author(s):  
Tomoko Nakazawa ◽  
Megumi Nishikawa ◽  
Eizo Aikawa ◽  
Masao Mato
Keyword(s):  
In Vitro Characterization ◽  
Rat Cerebrum

scholarly journals Developmental study of the chick embryo in vitro.

1988 ◽  
Vol 25 (1) ◽  
pp. 27-33
Author(s):  
Kazufumi GOTO ◽  
Yoko TAKAHASHI ◽  
Yoshihiko NAKANISHI ◽  
Kiyohiko OGAWA
Keyword(s):  
Chick Embryo ◽  
Developmental Study

scholarly journals In vitro developmental study of oil palm (Elaeis guineensis Jacq.) polyembryoids from cell suspension using scanning electron microscopy

2013 ◽  
Vol 35 (5) ◽  
pp. 1727-1733 ◽  
Author(s):  
Sharrmila Rengeswari Palanyandy ◽  
Periasamy Suranthran ◽  
Saikat Gantait ◽  
Uma Rani Sinniah ◽  
Sreeramanan Subramaniam ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Cell Suspension ◽  
Oil Palm ◽  
Elaeis Guineensis ◽  
Developmental Study ◽  
Elaeis Guineensis Jacq ◽  
Scanning Electron

scholarly journals Myosin heavy chain gene expression in mouse embryoid bodies. An in vitro developmental study.

1991 ◽  
Vol 266 (33) ◽  
pp. 22419-22426
Author(s):  
A. Sánchez ◽  
W.K. Jones ◽  
J. Gulick ◽  
T. Doetschman ◽  
J. Robbins
Keyword(s):  
Gene Expression ◽  
Myosin Heavy Chain ◽  
Heavy Chain ◽  
Embryoid Bodies ◽  
Chain Gene ◽  
Developmental Study ◽  
Heavy Chain Gene ◽  
Myosin Heavy Chain Gene
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