Vacuum freeze-drying kinetics and modelling of a liquid in a vial

Author(s):  
E. Wolff ◽  
H. Gibert ◽  
F. Rodolphe
Author(s):  
Petra Foerst ◽  
M. Lechner ◽  
N. Vorhauer ◽  
H. Schuchmann ◽  
E. Tsotsas

The pore structure is a decisive factor for the process efficiency and product quality of freeze dried products. In this work the two-dimensional ice crystal structure was investigated for maltodextrin solutions with different concentrations by a freeze drying microscope. The resulting drying kinetics was investigated for different pore structures. Additionally the three-dimensional pore structure of the freeze dried samples was measured by µ-computed tomography and the pore size distribution was quantified by image analysis techniques. The two- and three-dimensional pore size distributions were compared and linked to the drying kinetics.Keywords: pore size distribution; freeze drying; maltodextrin solution; freeze drying microscope   


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Vol 62 (1) ◽  
pp. 7-17
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Adina Ghirişan ◽  
◽  
Simion Drăgan ◽  
Vasile Miclăuş ◽  
◽  
...  

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J. M. Saiter ◽  
N. Delahaye ◽  
A. Bardat ◽  
E. Chatenet

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Ashutosh Singh ◽  
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Akinbode Adedeji ◽  
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Clara Carrión ◽  
Antonio Mulet ◽  
José V. García-Pérez ◽  
Juan A. Cárcel

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Vol 92 (9) ◽  
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Author(s):  
P. Levin ◽  
V. Meunier ◽  
S. Palzer ◽  
S. Heinrich

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Vol 2 (2) ◽  
pp. 124-129 ◽  
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