Effect of pelvic radiation therapy on protein-energy nutritional status in patients with carcinoma of the uterus

Abstract Background and Aims Fatigue is a symptom with a high prevalence in patients on hemodialysis therapy due to uremic toxins, anemia, associated comorbidity, and hemodialysis treatment per se. Our objective is to evaluate the prevalence of fatigue reported by patients and their association with the nutritional status. Method This was a prospective observational, multicenter cohort study. Prevalent patients on HD therapy for at least 90 days, older than 18, at the Baxter Renal Care Services were included between September 1, 2017, to November 30, 2017 with one-year follow-up. Socio-demographic and clinical characteristics of all patients were summarized descriptively, the nutritional status was evaluated by protein Energy waste (PEW). Patient reported fatigue was measured with high flux membrane and medium cut-off membrane (Theranova). A generalized linear binomial multivariable model was conducted to assess the effect of PEW on fatigue symptom controlling for some confounding variables. Results We found that the fatigue reported by the patients has a prevalence of 55% [95% CI: 52.2 to 57.7] in our population, there are no statistical differences due to the use of different types of membranes p= 0.911, and neither did we find that the nutritional status is an independent factor that explains this symptom. If we find that women and diabetics have a higher risk of fatigue; RR=1.17 [95% CI: 1.06 to 1.29] and RR= 1.19 [95% CI: 1.00 to 1.42] respectively. Conclusion The fatigue is a prevalent symptom in the chronic hemodialysis population; being a woman and the diagnosis of diabetes are risk factors associated with this outcome. PEW and the type of dialysis membrane used were not associated with this symptom. Studies evaluating the recovery time from post-dialysis symptoms and its relationship with the type of membrane are necessary.

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Can Dosimetric Parameters Predict Acute Hematologic Toxicity in Rectal Cancer Patients Treated With Intensity Modulated Pelvic Radiation Therapy?

International Journal of Radiation Oncology*Biology*Physics ◽

10.1016/j.ijrobp.2015.07.495 ◽

2015 ◽

Vol 93 (3) ◽

pp. S206

Author(s):

J. Wan

Keyword(s):

Rectal Cancer ◽

Radiation Therapy ◽

Cancer Patients ◽

Hematologic Toxicity ◽

Pelvic Radiation ◽

Intensity Modulated

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Nutritional Status of Participating and Non-participating Pupils in the Ghana School Feeding Programme

Journal of Food Research ◽

10.5539/jfr.v1n3p263 ◽

2012 ◽

Vol 1 (3) ◽

pp. 263 ◽

Cited By ~ 10

Author(s):

A. O. Danquah ◽

A. N. Amoah ◽

M. Steiner-Asiedu ◽

C. Opare-Obisaw

Keyword(s):

Nutritional Status ◽

School Children ◽

Protein Energy Malnutrition ◽

School Lunch ◽

Nutrient Deficiencies ◽

Demographic Health Survey ◽

School Feeding ◽

Protein Energy ◽

Significant Difference ◽

Better Than

The Ghana Demographic Health Survey indicates that the major nutritional challenges in Ghana among school children are protein-energy malnutrition and micro-nutrient deficiencies. School Feeding Programmes are one of the main interventions addressing malnutrition and its related effects on children’s health and education. The purpose of this study was to assess the influence of Ghana School Feeding Programme on nutritional status of school children in Atwima-Nwabiagya District of Ashanti Region, Ghana. A total of 234 pupils between 9 and 17 years of age, comprising 114 participants and 120 non-participants from three participating and three non-participating schools, respectively, with similar characteristics, took part in the study. It was hypothesized that the nutritional status of participants was better than that of non-participants. Results did not indicate any association between the school lunch and nutritional status. There was no statistically significant difference in the nutritional status of participants and non-participants. The programme did not impact the nutritional status of participants.

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MALNUTRITION IN CIRRHOSIS: ASSOCIATION WITH ETIOLOGY AND HEPATOCELLULAR DYSFUNCTION

Arquivos de Gastroenterologia ◽

10.1590/s0004-2803.202000000-71 ◽

2020 ◽

Vol 57 (4) ◽

pp. 375-380

Author(s):

Kalinca S OLIVEIRA ◽

Luana Reis OLIVEIRA ◽

Sabrina A FERNANDES ◽

Gabriela P CORAL

Keyword(s):

Liver Disease ◽

Nutritional Status ◽

Protein Energy Malnutrition ◽

Muscle Thickness ◽

Bioelectrical Impedance ◽

Disease Etiology ◽

Adductor Pollicis Muscle ◽

Protein Energy ◽

End Stage ◽

A Prospective Study

ABSTRACT BACKGROUND: The protein-energy malnutrition alters the prognosis of patients with cirrhosis. Its prevalence may vary according to the etiology of liver disease, it´s severity and the evaluation of the method applied. The infection by the hepatitis C virus (HCV) and alcoholism are the main etiologies of cirrhosis and result in a significant morbidity and mortality. OBJECTIVE: To evaluate the nutritional status of patients with cirrhosis according the liver disease etiology and severity. METHODS: It is a prospective study, in which the sample was for convenience and consisted of patients with cirrhosis, infected by HCV or alcoholic etiology. The nutritional status evaluation was carried out through anthropometry, food consumption, bioelectrical impedance (BIA) and subjective global assessment (SGA). The anthropometric data evaluated were weight, height, body mass index (BMI), triceps skinfold (TSF), circumference of the arm (CA), non-dominant handshake strength (FAM) and the adductor pollicis muscle thickness (APM). Patients were classified according to the severity of liver disease, using the Child-Pugh and Model for End-stage Liver Diseases (MELD) scores. RESULTS: Ninety patients with cirrhosis were evaluated, 47 with HCV and 43 with alcoholic etiology. The prevalence of protein-calorie malnutrition ranged from 10.9% to 54.3% in the HCV group and from 4.7% to 20.9% in the alcoholic group, depending on the method used for evaluation. The group with HCV infection presented a higher malnutrition prevalence in comparison to the alcoholic in the following evaluations: TSF (P<0.001), phase angle (PA) (P=0.016) and SGA (P=0.010). PA values were lower in patients with viral cirrhosis (5.68±1.05) when compared to those with alcoholic etiology (6.61±2.31) (P=0.016). When all patients were analyzed, regardless of etiology, an inversely correlation was observed among Child-Pugh score and PA values (P=0.018). CONCLUSION: HCV cirrhosis showed worse nutritional parameters in comparison to alcoholic etiology; however, the PA was associated with worse liver function in both etiologies.

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