Diagnostic and clinical implications of the different genotypes of hepatitis C virus Nagayama R, Tsuda F, Okamoto H, Wang Y, Mitsui T, Tanaka T, Miyakawa Y, Mayumi M. Genotype dependence of hepatitis C virus antibodies detectable by the first-generation enzyme-linked immunosorbent assay with C100-3 protein. J Clin Invest 1993;92:1529?1533

Hepatology ◽  
1994 ◽  
Vol 20 (1) ◽  
pp. 256-259 ◽  
Author(s):  
J BUKH
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Immunosorbent Assay ◽  
First Generation ◽  
Enzyme Linked Immunosorbent Assay ◽  
Clinical Implications

Performance of an Enzyme-Linked Immunosorbent Assay System for Antibodies to Hepatitis C Virus with Two New Antigens (c11/c7)

1992 ◽  
Vol 38 (12) ◽  
pp. 2434-2439 ◽  
Author(s):  
M Saito ◽  
A Hasegawa ◽  
T Kashiwakuma ◽  
M Kohara ◽  
M Sugi ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Acute Hepatitis ◽  
Immunosorbent Assay ◽  
First Generation ◽  
Early Stage ◽  
Enzyme Linked Immunosorbent Assay ◽  
Elisa System ◽  
Hcv Antibody ◽  
Assay Precision

Abstract We developed an enzyme-linked immunosorbent assay (ELISA) system for antibodies to the hepatitis C virus (HCV), using two new recombinant antigens (c11 and c7) derived from the HCV genome. The performance of this ELISA system (Imucheck HCV Ab) was examined. The CV values for both intra-assay precision and reproducibility of identifying HCV antibody in the panel sera ranged from 3.5% to 6.4%. The blood elements in serum and anticoagulants did not interfere in this ELISA system. The specificity of Imucheck HCV Ab to samples from patients with non-A, non-B (NANB)-type chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma was 93.7%, 93.5%, and 81.4%, respectively. These results are more sensitive than those obtained by the first-generation anti-HCV ELISA system. In the samples from patients with NANB-type acute hepatitis, Imucheck HCV Ab enabled detection of HCV antibodies at an early stage. This system increased the sensitivity for blood donor screening and for monitoring patients with acute hepatitis.

An Enzyme-Linked Immunosorbent Assay for Detecting Proteolytic Activity of Hepatitis C Virus Proteinase

1997 ◽  
Vol 247 (2) ◽  
pp. 242-246 ◽  
Author(s):  
Norisue Takeshita ◽  
Nobuko Kakiuchi ◽  
Tsutomu Kanazawa ◽  
Yasumasa Komoda ◽  
Makoto Nishizawa ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Proteolytic Activity ◽  
Immunosorbent Assay ◽  
Enzyme Linked Immunosorbent Assay

scholarly journals High Frequency of False-Positive Hepatitis C Virus Enzyme-Linked Immunosorbent Assay in Rakai, Uganda

2013 ◽  
Vol 57 (12) ◽  
pp. 1747-1750 ◽  
Author(s):  
C. E. Mullis ◽  
O. Laeyendecker ◽  
S. J. Reynolds ◽  
P. Ocama ◽  
J. Quinn ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Immunosorbent Assay ◽  
False Positive ◽  
High Frequency ◽  
Enzyme Linked Immunosorbent Assay
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