The efficiency of growth during body weight recovery in young adult female rats

1987 ◽  
Vol 87 (3) ◽  
pp. 547-549 ◽  
Author(s):  
Vernon J Williams ◽  
James W Sheedy
Keyword(s):  
Body Weight ◽  
Young Adult ◽  
Adult Female ◽  
Female Rats

Dissimilar Anxiety-like Behavior in Prepubertal and Young Adult Female Rats on Acute Exposure to Aluminium

2021 ◽  
Vol 22 ◽  
Author(s):  
Trina Sengupta ◽  
Sutirtha Ghosh ◽  
Archana Gaur T. ◽  
Prasunpriya Nayak
Keyword(s):  
Body Weight ◽  
Young Adult ◽  
Adult Female ◽  
Developmental Stages ◽  
Elevated Plus Maze ◽  
Age Groups ◽  
Female Rats ◽  
Acute Exposure ◽  
Adult Rats ◽  
Plus Maze

Background: Puberty is a developmental transition in which an estrogenic surge occurs, mediating the release of xenoestrogens, like aluminium. Aluminium’s effect on anxiety in rodents at the different developmental stages is inconsistent. Aims: This study aimed at investigating the effect of the metalloestrogenic property of aluminium on anxiety-like behavioral changes in prepubertal and young adult female rats. Objective: Considering this aim, our objective was to evaluate the anxiety-like behavior by the elevated plus maze in prepubertal and young adult female rats with or without acute exposure to aluminium. Methods: To address this property of aluminium, 5mg/Kg body weight (Al-5) and 10 mg/Kg body weight (Al-10) of aluminium was administered intraperitoneally to female rats at two developmental stages, prepubertal (PP; n = 8 for each dose) and young adult (YA; n = 6 for each dose) for two weeks. Post-treatment, three days behavioral assessment of the rats was done employing elevated plus maze. Results: Reduced escape latency was seen in Al-5, Al-10 pre-pubertal rats, and Al-5 young-adult rats on day 3. A significant reduction in open arm time was seen in the Al-5 young-adult rats. Aluminium treatment in the pre-pubertal rats reduced their head dipping and grooming. Reduced sniffing, head dipping, and stretch-attended posture in the treated young-adult female rats showed that they had impaired risk-taking tendency. Conclusion: Differential effect on the anxiety-like behavior in the pre-pubertal and young-adult female rats might be due to the metalloestrogenic property of aluminium, acting differently on the two age groups.

scholarly journals Changes in Body Composition and Efficiency of Food Utilization for Growth in Young Adult Female Rats Before, During and After a Period of Food Restriction

1979 ◽  
Vol 32 (1) ◽  
pp. 41 ◽  
Author(s):  
VJ Williams ◽  
W Senior
Keyword(s):  
Body Composition ◽  
Body Weight ◽  
Young Adult ◽  
Food Intake ◽  
Adult Female ◽  
Body Weight Loss ◽  
Normal Growth ◽  
Female Rats ◽  
Food Utilization ◽  
Ad Libitum

Changes in body composition were studied in three groups of young adult female rats; the treatments were (1) ad libitum food intake to obtain normal growth, (2) restricted food intake to cause body weight loss, and (3) restricted followed by ad libitum food intake to obtain recovery of lost body weight.

scholarly journals The Effect of Semi-Starvation on the Digestibility of Food in Young Adult Female Rats

1978 ◽  
Vol 31 (6) ◽  
pp. 593 ◽  
Author(s):  
VJ Williams ◽  
W Senior
Keyword(s):  
Body Weight ◽  
Organic Matter ◽  
Young Adult ◽  
Food Intake ◽  
Adult Female ◽  
Female Rats ◽  
Ad Libitum ◽  
Second Period

The apparent digestibilities of organic matter, protein, lipid and carbohydrate of a laboratory chow were determined in young adult female rats fed ad libitum, after losing 40-50%body weight and prolonging the loss for up to 15 weeks, and while recovering the lost body weight during .. a second period of ad libitum food intake.

Regrowth of atrophied skeletal muscle in adult rats after ending immobilization

1978 ◽  
Vol 44 (2) ◽  
pp. 225-230 ◽  
Author(s):  
F. W. Booth
Keyword(s):  
Skeletal Muscle ◽  
Body Weight ◽  
Adult Female ◽  
Total Protein ◽  
Recovery Time ◽  
Time Course ◽  
Citrate Synthase ◽  
Female Rats ◽  
Adult Rats ◽  
Wet Weight

The recovery time course of muscle atrophied by immobilization was followed after removal of hindlimb casts from adult female rats. Increases of only 9% in body weight, 4% in gastrocnemius weight, and 10% in soleus weight occurred in controls during the 78-day duration of the experiment. There were no increases in the amounts of total protein or of citrate synthase activities in gastrocnemius or soleus during the first 3 days after removal of hindlimb casts; thereafter, there were increases in these paramters. Citrate synthase activities per mg of gastrocnemius protein were significantly higher at the 16th and 50th day of recovery. No significant differences for citrate synthase activity per mg of soleus occurred during recovery. Until the 50th day of recovery, no significant differences for total protein in soleus and for total protein and wet weight of gastrocnemius were observed between control and recovery values. However, the wet weight of the soleus returned rapidly during recovery and was not significantly different from control during recovery.

scholarly journals Acute genistein treatment mimics the effects of estradiol by enhancing place learning and impairing response learning in young adult female rats

2012 ◽  
Vol 62 (4) ◽  
pp. 491-499 ◽  
Author(s):  
Samantha L. Pisani ◽  
Steven L. Neese ◽  
Daniel R. Doerge ◽  
William G. Helferich ◽  
Susan L. Schantz ◽  
...  
Keyword(s):  
Young Adult ◽  
Adult Female ◽  
Place Learning ◽  
Female Rats ◽  
Response Learning ◽  
Genistein Treatment

Effect of chronic administration of insulin on pituitary gland content of growth hormone in the normal rat

1970 ◽  
Vol 48 (2) ◽  
pp. 85-89 ◽  
Author(s):  
Robert L. Hazelwood ◽  
John G. Galaznik
Keyword(s):  
Growth Hormone ◽  
Body Weight ◽  
Young Adult ◽  
Pituitary Gland ◽  
Chronic Administration ◽  
Female Rats ◽  
Pituitary Glands ◽  
Hypophysectomized Rats ◽  
Normal Rat ◽  
Gland Content

Acetone-dried pituitary glands from young adult female rats (starting weight 165–168 g) previously injected (s.c.) with doses of insulin of 0.5 U to 1.0 U/kg body weight for 4 days, and then with 2.0 U/kg 6 days a week for an additional 34 days, were bioassayed in young hypophysectomized rats for growth hormone content. Insulin-injected rats gained significantly more weight than saline-injected controls. The tibia cartilage width of the insulin-injected donor rats was greater than that of control rats after 9, 17, 24, and 31 days of insulin; pituitary gland preparations from these insulin-injected rats increased tibia cartilage widths slightly but significantly over those of rats injected with control pituitary gland preparations.

scholarly journals The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female rats

2000 ◽  
Vol 165 (3) ◽  
pp. 569-577 ◽  
Author(s):  
J Svensson ◽  
S Lall ◽  
SL Dickson ◽  
BA Bengtsson ◽  
J Romer ◽  
...  
Keyword(s):  
Body Weight ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Adult Female ◽  
Mineral Content ◽  
Female Rats ◽  
Volumetric Bmd ◽  
Ash Weight

Growth hormone (GH) is of importance for normal bone remodelling. A recent clinical study demonstrated that MK-677, a member of a class of GH secretagogues (GHSs), increases serum concentrations of biochemical markers of bone formation and bone resorption. The aim of the present study was to investigate whether the GHSs, ipamorelin (IPA) and GH-releasing peptide-6 (GHRP-6), increase bone mineral content (BMC) in young adult female rats. Thirteen-week-old female Sprague-Dawley rats were given IPA (0.5 mg/kg per day; n=7), GHRP-6 (0.5 mg/kg per day; n=8), GH (3.5 mg/kg per day; n=7), or vehicle administered continuously s.c. via osmotic minipumps for 12 weeks. The animals were followed in vivo by dual X-ray absorptiometry (DXA) measurements every 4th week. After the animals were killed, femurs were analysed in vitro by mid-diaphyseal peripheral quantitative computed tomography (pQCT) scans. After this, excised femurs and vertebrae L6 were analysed by the use of Archimedes' principle and by determinations of ash weights. All treatments increased body weight and total tibial and vertebral BMC measured by DXA in vivo compared with vehicle-treated controls. However, total BMC corrected for the increase in body weight (total BMC:body weight ratio) was unaffected. Tibial area bone mineral density (BMD, BMC/area) was increased, but total and vertebral area BMDs were unchanged. The pQCT measurements in vitro revealed that the increase in the cortical BMC was due to an increased cross-sectional bone area, whereas the cortical volumetric BMD was unchanged. Femur and vertebra L6 volumes were increased but no effect was seen on the volumetric BMDs as measured by Archimedes' principle. Ash weight was increased by all treatments, but the mineral concentration was unchanged. We conclude that treatment of adult female rats with the GHSs ipamorelin and GHRP-6 increases BMC as measured by DXA in vivo. The results of in vitro measurements using pQCT and Archimedes' principle, in addition to ash weight determinations, show that the increases in cortical and total BMC were due to an increased growth of the bones with increased bone dimensions, whereas the volumetric BMD was unchanged.

THE INFLUENCE OF SUCKLING ON FOOD INTAKE AND GROWTH OF ADULT FEMALE RATS

1954 ◽  
Vol 10 (4) ◽  
pp. 363-367 ◽  
Author(s):  
P. MARY COTES ◽  
B. A. CROSS
Keyword(s):  
Body Weight ◽  
Food Intake ◽  
Adult Female ◽  
Post Partum ◽  
Female Rats ◽  
Milk Secretion ◽  
Growth Increments ◽  
Main Factor

SUMMARY Changes in body weight and food intake were studied for 14 days post partum in primiparous rats. The growth increments in suckled rats with galactophores cut to prevent milk withdrawal and in normally lactating rats were greater than in unsuckled controls. The growth increments in rats with galactophores cut were accompanied by parallel increases in food intake. Injection of 3 i.u. prolactin daily did not reproduce these changes in body weight and food intake in non-suckled rats. The results suggest that the main factor in the extra growth of lactating rats is an increased food intake in excess of the metabolic needs for milk secretion induced by the stimulus of suckling.

Effect of the Contraceptive Steroids Norethynodrel and Mestranol on Dental Caries Activity in Young Adult Female Rats

1973 ◽  
Vol 52 (4) ◽  
pp. 753-757 ◽  
Author(s):  
F.T.Y. Liu ◽  
H.S. Lin
Keyword(s):  
Young Adult ◽  
Dental Caries ◽  
Adult Female ◽  
Female Rats ◽  
Test Diet ◽  
Caries Activity ◽  
Contraceptive Steroids ◽  
Carious Lesions

Norethynodrel and mestranol in a ratio identical to that used for contraception were injected subcutaneously daily for five weeks into young adult female rats. These rats were fed with a purified caries test diet. The carious lesions of the treated rats increased proportionately with increased doses of the agents.

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