17. Characterization of mcl-1, a gene expressed in the early stages of myeloid leukemia cell differentiation

1992 ◽  
Vol 46 (5-7) ◽  
pp. 246
Author(s):  
RW Craig ◽  
KM Kozopas ◽  
T Yang ◽  
HL Buchan ◽  
P Zhou
Keyword(s):  
Cell Differentiation ◽  
Myeloid Leukemia ◽  
Leukemia Cell ◽  
Early Stages ◽  
Myeloid Leukemia Cell

Establishment and characterization of a novel CD34-positive human myeloid leukemia cell line: MHH225 growing in serum-free culture

1995 ◽  
Vol 71 (3) ◽  
pp. 111-117
Author(s):  
H. T. Hassan ◽  
E. Petershofen ◽  
E. Lux ◽  
C. Fonatsch ◽  
G. Heil ◽  
...  
Keyword(s):  
Cell Line ◽  
Myeloid Leukemia ◽  
Leukemia Cell ◽  
Leukemia Cell Line ◽  
Serum Free ◽  
Myeloid Leukemia Cell

scholarly journals Enasidenib induces acute myeloid leukemia cell differentiation to promote clinical response

Blood ◽  
2017 ◽  
Vol 130 (6) ◽  
pp. 732-741 ◽  
Author(s):  
Michael D. Amatangelo ◽  
Lynn Quek ◽  
Alan Shih ◽  
Eytan M. Stein ◽  
Mikhail Roshal ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
Myeloid Leukemia ◽  
Response Rate ◽  
Leukemia Cell ◽  
Leukemic Cell ◽  
Ras Pathway ◽  
Mutational Burden ◽  
Key Points ◽  
Acute Myeloid ◽  
Myeloid Leukemia Cell

Key Points Enasidenib inhibits mIDH2, leading to leukemic cell differentiation with emergence of functional mIDH2 neutrophils in rrAML patients. RAS pathway mutations and increased mutational burden overall are associated with a decreased response rate to mIDH2 inhibition.

Establishment and Characterization of a New Ph1-Positive Chronic Myeloid Leukemia Cell Line MC3 with Trilineage Phenotype and an Altered p53 Gene

1995 ◽  
Vol 16 (5-6) ◽  
pp. 493-503 ◽  
Author(s):  
Mihiro Okabe ◽  
Yasuyuki Kunieda ◽  
Shingo Nakane ◽  
Mitsutoshi Kurosawa ◽  
Toshiyuki Itaya ◽  
...  
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Cell Line ◽  
Myeloid Leukemia ◽  
Leukemia Cell ◽  
P53 Gene ◽  
Leukemia Cell Line ◽  
Chronic Myeloid Leukemia Cell ◽  
Myeloid Leukemia Cell
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