MRI study of corpus callosum, ventricular volume, and whole brain volume

1993 ◽  
Vol 9 (2-3) ◽  
pp. 212-213
Author(s):  
D.A. Yurgelun-Todd ◽  
S.W. Brennan ◽  
S. Gruber ◽  
B.T. Woods
Keyword(s):  
Corpus Callosum ◽  
Brain Volume ◽  
Ventricular Volume ◽  
Whole Brain ◽  
Mri Study

P.1.e.028 Increase of whole brain volume and gray and white matter tissue in OCD: a volumetric and voxel-based morphometry MRI study

2010 ◽  
Vol 20 ◽  
pp. S303-S304
Author(s):  
T. Sobanski ◽  
G. Wagner ◽  
G. Peikert ◽  
U. Gruhn ◽  
H. Sauer ◽  
...  
Keyword(s):  
White Matter ◽  
Brain Volume ◽  
Voxel Based Morphometry ◽  
Whole Brain ◽  
Mri Study

Pathological cut-offs of global and regional brain volume loss in multiple sclerosis

2017 ◽  
Vol 25 (4) ◽  
pp. 541-553 ◽  
Author(s):  
Tomas Uher ◽  
Manuela Vaneckova ◽  
Jan Krasensky ◽  
Lukas Sobisek ◽  
Michaela Tyblova ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Grey Matter ◽  
Brain Volume ◽  
Healthy Controls ◽  
Volume Loss ◽  
Whole Brain ◽  
Brain Volume Loss ◽  
Regional Brain ◽  
Mri Scans ◽  
Regional Brain Volume

Background: Volumetric MRI surrogate markers of disease progression are lacking. Objective: To establish cut-off values of brain volume loss able to discriminate between healthy controls and MS patients. Methods: In total, 386 patients after first demyelinating event suggestive of MS (CIS), 964 relapsing-remitting MS (RRMS) patients, 63 secondary-progressive MS (SPMS) patients and 58 healthy controls were included in this longitudinal study. A total of 11,438 MRI scans performed on the same MRI scanner with the same protocol were analysed. Annualised percentage changes of whole brain, grey matter, thalamus and corpus callosum volumes were estimated. We investigated cut-offs able to discriminate between healthy controls and MS patients. Results: At a predefined specificity of 90%, the annualised percentage change cut-off of corpus callosum volume (−0.57%) was able to distinguish between healthy controls and patients with the highest sensitivity (51% in CIS, 48% in RRMS and 42% in SPMS patients). Lower sensitivities (22%−49%) were found for cut-offs of whole brain, grey matter and thalamic volume loss. Among CIS and RRMS patients, cut-offs were associated with greater accumulation of disability. Conclusion: We identified cut-offs of annualised global and regional brain volume loss rates able to discriminate between healthy controls and MS patients.

On the anatomic relation of choroid plexus to brain: a comparative study

1980 ◽  
Vol 238 (1) ◽  
pp. R76-R81 ◽  
Author(s):  
H. F. Cserr ◽  
M. Bundgaard ◽  
J. K. Ashby ◽  
M. Murray
Keyword(s):  
Choroid Plexus ◽  
Brain Volume ◽  
Brain Size ◽  
Ventricular Volume ◽  
Brain Weight ◽  
Air Breathing ◽  
Original Proposal ◽  
Adaptive Value ◽  
Choroid Plexuses ◽  
The Brain

The size of choroid plexuses and cerebral ventricles relative to brain varies widely among vertebrates. The functional significance of this variability has attracted little attention since Herrick's original proposal that large choroid plexuses might enhance oxygen delivery to the brain and therefore be of adaptive value in the transition of vertebrates from water to air breathing. We compared choroid plexus and brain weight or ventricular and brain volume in 40 species from nine vertebrate groups. Both choroid plexus weight and ventricular volume were unrelated to brain size. Plexus weight ranged from 0 to 5.2% of brain weight and ventricular volume from 0.9 to 132% of brain volume. Amid this diversity the dipnoans, chondrosteans, holosteans, amphibians, and crossopterygian examined in this study are exceptional in uniformly having large plexuses. The adaptive significance of large choroid plexuses may lie in the presence of specific homeostatic mechanisms and their role in the response to the increases in PCO2 that accompany the transition to air breathing.

Maudsley family study: Whole brain volume changes in sporadic schizophrenics and their first degree relatives

2000 ◽  
Vol 41 (1) ◽  
pp. 126
Author(s):  
A. Grech ◽  
T. Toulopoulou ◽  
T. Sharma ◽  
J. Yakeley ◽  
R.M. Murray
Keyword(s):  
Family Study ◽  
Brain Volume ◽  
Volume Changes ◽  
Whole Brain ◽  
First Degree Relatives

Serial MRI in multiple sclerosis: a prospective pilot study of lesion load, whole brain volume and thalamic atrophy

2004 ◽  
Vol 11 (2) ◽  
pp. 153-158 ◽  
Author(s):  
I Taylor ◽  
H Butzkueven ◽  
L Litewka ◽  
L.R MacGregor ◽  
C Szoeke ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Pilot Study ◽  
Brain Volume ◽  
Lesion Load ◽  
Whole Brain ◽  
Prospective Pilot Study ◽  
Serial Mri
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