Quality of life in a methadone maintenance program

1993 ◽  
Vol 3 (3) ◽  
pp. 411 ◽  
Author(s):  
M. Torrens ◽  
L. San ◽  
E. Garrell ◽  
C. Castillo ◽  
A. Martinez ◽  
...  
2017 ◽  
Vol 74 (5) ◽  
pp. 435-444
Author(s):  
Mirjana Marinkovic ◽  
Lidija Djordjevic-Jovanovic ◽  
Snezana Miljkovic ◽  
Bobana Milojkovic ◽  
Vladimir Janjic

Background/Aim. Although the characteristics of the treatment are the most researched determinants of quality of life of opiate addicts, it is indisputable that there is a certain influence of the characteristics of addicts and addiction, too. The aim of this study was to determine which addicts characteristics, as well as the characteristics of the addiction and treatment have predicative influence on the quality of life of the opiate addicts treated in the methadone maintenance program and those treated with buprenorphine. Methods. The epidemiological cross-sectional study was carried out in 2013 at the Clinical Center Nis, on a total of 64 opiate addicts, both sexes, aged 18 and older (32 addicts in the methadone program, chosen by random selection, and 32 addicts treated with buprenorphine, matched by sex and age). Necessary data were collected in a ?face to face? interview with the examinees, based on the autonomous kind of a questionnaire, together with the use of the standardized World Health Organization (WHO) instruments: for health status, for the level of severity of addiction and for the quality of life measuring) based on which the health index (EQ-5D), Addiction Severity Index (ASI) and the quality of life index (WHOQOL-BREF) were calculated. The data were described by the methods of descriptive statistics, while the differences between groups were analyzed by applying ?2 and t-test. Multiple regressions were used to determine the predictors. Results. The addicts in the methadone program showed much worse perception of quality of life than those treated in another way, although, according to the values of quality of life, they did not differ significantly. The most numerous predictors of the level of quality of life were health characteristics, characteristics of the socioeconomic position of the examinees, as well as different consequences of addiction. The influence of treatment was less noticeable. Participating in the methadone program had predicative influence on perception and the level of quality of life of the addicts in mental area and that of the environment. The influence of the characteristics of methadone treatment in physical and social area was insignificant. Conclusion. Variations in the perception and level of the quality of life of opiate addicts in different areas cannot be explained using only one predictor. The number of determining variables is large, and its impact complex.


Medicina ◽  
2010 ◽  
Vol 46 (4) ◽  
pp. 286 ◽  
Author(s):  
Giedrius Vanagas ◽  
Žilvinas Padaiga ◽  
Eugenijus Bagdonas

Background. Economic evaluations in health care involve the identification, measurement, valuation, and then comparison of the costs (inputs) and outcomes of treatments or preventive activities. The aim was to analyze the cost-utility of six-month methadone maintenance treatment program in a Lithuanian primary health care setting. Methods. A prospective study design was used. All the information was obtained through the validated questionnaires at the baseline and 3- and 6-month follow-ups. WHOQOL-BREF was used to assess the quality of life; the costs were assessed using the DATCAP methodology from the perspective of a patient and outpatient clinic during follow-up period. Results. A total of 102 opioid-dependent patients were recruited in the study; 512 follow-up patient-months were obtained. The methadone maintenance treatment has significantly improved physical, psychological, and environmental components of quality of life during follow-up. Total program costs were 61 288.87 EUR. Cost paid by a patient comprised about 31% of total program costs. Cost per quality-adjusted life-month (QALM) for physical domain was 2227.55 EUR; for psychological domain, 1879.50 EUR; for social domain, 5467.64 EUR; and for environmental domain, 4626.47 EUR. Costs per QALM and quality-adjusted life-year (QALY) for total quality of life in the maintenance program were 2864.00 EUR and 34 368.00 EUR, respectively. Conclusions. Our results showed that 6-month methadone maintenance program was effective in the terms of quality-of-life improvement. Methadone maintenance treatment program was less effective in terms of cost per QALY.


1981 ◽  
Vol 26 (1) ◽  
pp. 43-48 ◽  
Author(s):  
N. El-Guebaly ◽  
W.J. Davidson ◽  
H.A. Sures ◽  
W. Griffin

An overview is presented of the status of human saliva as a clinical monitoring medium in medicine and psychiatry. Despite the present controversy about the reliability of saliva lithium levels, an evaluation of the prospects of saliva for other pharmacokinetic estimations as well is recommended. The second part of the paper outlines the authors’ attempt to expand the use of saliva monitoring in a depot neuroleptic clinic and a methadone maintenance program. This technique, well accepted by the patient populations, is found useful as a screening tool for drug use and compliance can be checked. It can also be indicated prior to the evaluation of the toxicity of prescribed medication as well as the assessment of drug interaction. On humanitarian, clinical and economical grounds, further investigation of the clinical applications of saliva in psychiatric practice is warranted.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
M. Hasanović ◽  
I. Pajević

Methadone maintenance program in Bosnia-Herzegovina (BH) has been introduced in Sarajevo for the first time in 1989 year. During the war years 1992-95, only sporadic cases of drug addicts, because of overdosing or because of toxic psychotic states were treated. Number of addicts increased in BH, especially after the war, and needed adequate solution of the problem as well as use of the experiences from the other countries that faced us before, "epidemy" of addictions. One of the solutions for harm reduction caused by use of opioid substances, primarily heroin, was use of methadone, which is a good replacement pharmacological. After opening the Unit for drug addiction in year 2000 in Sarajevo, the methadone program of detoxifying and maintenance was re-established in 2002. Nowadays in BH high-threshold methadone program is used in five centres, in accordance with the criteria for European guides for methadone therapy. In addition to the subject of methadone programs, there are serious preparations for the use of Suboxone (Buprenorphine+Naloxone) in BH. The basic component of medicine (Buprenorphine) was placed on the essential list of the World Health Organisation (WHO) in September 2005. In BH, this drug was registered 18.12.2007 year. At the Clinic for Psychiatry in Tuzla, the establishing of Suboxone maintenance program was planned for the autumn of 2008.


CMAJ Open ◽  
2016 ◽  
Vol 4 (3) ◽  
pp. E431-E435 ◽  
Author(s):  
Michel Landry ◽  
Nadia Veilleux ◽  
Julie-Eve Arseneault ◽  
Saneea Abboud ◽  
André Barrieau ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Tibor Hortobágyi ◽  
Dávid Sipos ◽  
Gábor Borbély ◽  
György Áfra ◽  
Emese Reichardt-Varga ◽  
...  

Introduction: There are scant data to demonstrate that the long-term non-pharmaceutical interventions can slow the progression of motor and non-motor symptoms and lower drug dose in Parkinson's disease (PD).Methods: After randomization, the Exercise-only (E, n = 19) group completed an initial 3-week-long, 15-session supervised, high-intensity sensorimotor agility exercise program designed to improve the postural stability. The Exercise + Maintenance (E + M, n = 22) group completed the 3-week program and continued the same program three times per week for 6 years. The no exercise and no maintenance control (C, n = 26) group continued habitual living. In each patient, 11 outcomes were measured before and after the 3-week initial exercise program and then, at 3, 6, 12, 18, 24, 36, 48, 60, and 72 months.Results: The longitudinal linear mixed effects modeling of each variable was fitted with maximum likelihood estimation and adjusted for baseline and covariates. The exercise program strongly improved the primary outcome, Motor Experiences of Daily Living, by ~7 points and all secondary outcomes [body mass index (BMI), disease and no disease-specific quality of life, depression, mobility, and standing balance]. In E group, the detraining effects lasted up to 12 months. E+M group further improved the initial exercise-induced gains up to 3 months and the gains were sustained until year 6. In C group, the symptoms worsened steadily. By year 6, levodopa (L-dopa) equivalents increased in all the groups but least in E + M group.Conclusion: A short-term, high-intensity sensorimotor agility exercise program improved the PD symptoms up to a year during detraining but the subsequent 6-year maintenance program was needed to further increase or sustain the initial improvements in the symptoms, quality of life, and drug dose.


2018 ◽  
Vol 9 (2) ◽  
pp. 93-98
Author(s):  
Anggita Bunga Anggraini

Latar belakang: Salah satu penilaian keberhasilan Program Terapi Rumatan Metadon (PTRM) yang merupakanprogram rehabilitasi terhadap pengguna narkoba -- khususnya pengguna narkotika suntik -- adalah kualitashidup klien. Oleh karena itu perlu diidentifikasi beberapa faktor yang dominan mempengaruhinya. Metode: Penelitian dilakukan dengan desain potong lintang yang dilakukan di Puskesmas Kedung Badakdan Bogor Timur di Kota Bogor. Pengumpulan data dilakukan dengan wawancara dan pengisian kuesionerWHOQOL-BREF pada April-Juni 2018. Analisis dilakukan dengan menggunakan regresi linier multivariabel. Hasil: Responden dalam penelitian ini berjumlah 62 orang. Hasil penelitian menunjukkan rerata skor kualitashidup klien PTRM di Kota Bogor pada domain fisik sebesar 57,6; domain psikologis sebesar 57,5; domain sosialsebesar 63,6; dan domain lingkungan 63,9. Dibandingkan rerata skor populasi sehat di Indonesia, domain fisikdan psikologis lebih rendah daripada populasi tersebut, sedangkan domain psikologis tidak berbeda denganpopulasi tersebut. Adapun skor domain lingkungan lebih tinggi dibandingkan populasi sehat Indonesia. Faktoryang dominan dalam menentukan kualitas hidup pada domain fisik dan lingkungan adalah tingkat pendidikan,sedangkan domain psikologis adalah dosis metadon. Faktor yang dominan dalam menentukan kualitas hidupdomain sosial adalah adanya seseorang yang dapat diajak bicara. Kesimpulan: Semakin tinggi tingkat pendidikan klien, maka kualitas hidup klien pada seluruh domain akansemakin baik. Klien PTRM dengan tingkat pendidikan yang lebih rendah harus dipantau untuk meningkatkankualitas hidupnya. Penanganan klien dengan pendekatan individual dan dukungan sosial dari keluarga danteman diperlukan untuk meningkatkan motivasi serta kepatuhan klien dalam menjalani terapi metadon. (HealthScience Journal of Indonesia 2018;9(2):93-9) Kata kunci: Kualitas hidup, metadon Abstract Background: One of the objective in Methadone Maintenance Therapy (MMT) which is a rehabilitationprogram for injecting drug users is quality of life. The purpose of this study was to determine quality oflife among MMT patients. Methods: The cross sectional study was conducted in Kedung Badak Primary Health Care and BogorTimur in Bogor. Data were collected from interview and filling out WHOQOL-BREF questionnaire fromApril-June 2018. Analysis was performed using multiple linier regression. Results: Total subjects in this study was 62 subjects. The results showed mean scores for physical domainwas 57.6; psychological domain was 57.5; social domain was 63.6; and environmental domain was 63.9.Compared with Indonesian, MMT patient scores were higher in environmental domain and lower inphysical and psychological domain while social domain had no different with it. The dominant factor indetermining physical and environmental domain was level of education, while the psychological domainwas methadone dose, and the existence of someones to talk to was dominant factor for social domain. Conclusion: The higher level of education, will produce better quality of life in all domains. MMTpatients with lower level education must be monitored to improve their quality of life. It is suggested totreat patients based on individual approaches and support from family and friends is needed to motivateclients and adherence to the therapy. (Health Science Journal of Indonesia 2018;9(2):93-9) Keywords: Methadone, quality of life


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