Metabolic syndrome is a collective term that denotes disorder in metabolism, symptoms of
which include hyperglycemia, hyperlipidemia, hypertension, and endothelial dysfunction. Diet is a
major predisposing factor in the development of metabolic syndrome, and dietary intervention is
necessary for both prevention and management. The bioactive constituents of food play a key role in
this process. Micronutrients such as vitamins, carotenoids, amino acids, flavonoids, minerals, and
aromatic pigment molecules found in fruits, vegetables, spices, and condiments are known to have
beneficial effects in preventing and managing metabolic syndrome. There exists a well-established
relationship between oxidative stress and major pathological conditions such as inflammation, metabolic
syndrome, and cancer. Consequently, dietary antioxidants are implicated in the remediation of
these complications. The mechanism of action and targets of dietary antioxidants as well as their
effects on related pathways are being extensively studied and elucidated in recent times. This review
attempts a comprehensive study of the role of dietary carotenoids in alleviating metabolic syndromewith
an emphasis on molecular mechanism-in the light of recent advances.
Role of the Immune System in Hypertension: Modulation by Dietary Antioxidants
