Stochastic Effects — Genetic Effects of Ionizing Radiation

1998 ◽  
pp. 344-364
Author(s):  
Edward L. Alpen
ANRI ◽  
2021 ◽  
Vol 0 (3) ◽  
pp. 69-76
Author(s):  
Vasyh Gayfutdinov

The article discusses the need to make changes to the regulatory documents that classify harmful and (or) dangerous production factors that stimulate and regulate the work of workers under the influence of ionizing radiation based on the concept of a linear dependence of the risk of stochastic effects on the received dose.


2016 ◽  
Vol 38 (4) ◽  
pp. 271-275
Author(s):  
Ye I Stepanova ◽  
V Yu Vdovenko ◽  
Zh A Misharina ◽  
V I Kolos ◽  
L P Mischenko

Aim: To study the genetic effects in children exposed to radiation in utero as a result of the Chornobyl nuclear power plant accident accounting the total radiation doses and equivalent radiation doses to the red bone marrow. Materials and Methods: Incidence of minor developmental anomalies was studied in children exposed to radiation in utero (study group) and in the control group (1144 subjects surveyed in total). Cytogenetic tests using the method of differential G-banding of chromosomes were conducted in 60 children of both study and control groups (10–12-year-olds) and repeatedly in 39 adolescents (15–17-year-olds). Results: A direct correlation was found between the number of minor developmental anomalies and fetal dose of radiation, and a reverse one with fetal gestational age at the time of radiation exposure. Incidence of chromosomal damage in somatic cells of 10–12-year-old children exposed prenatally was associated with radiation dose to the red bone marrow. The repeated testing has revealed that an increased level of chromosomal aberrations was preserved in a third of adolescents. Conclusion: The persons exposed to ionizing radiation at prenatal period should be attributed to the group of carcinogenic risk due to persisting increased levels of chromosome damage. This article is a part of a Special Issue entitled “The Chornobyl Nuclear Accident: Thirty Years After”.


2021 ◽  
Author(s):  
R Prahardi ◽  
◽  
Arundito Widikusumo

Ionizing radiation, when it hits our bodies, can ionize and excite the atomic nuclei of cells. Ionization and excitation will cause DNA damage either directly or indirectly. DNA damage is direct if ionizing radiation hits DNA, while DNA damage is indirectly through the formation of free radicals (atoms with unpaired electrons) and has a very damaging effect on DNA. Therefore, safety in ionizing radiation, including its use in the medical world, is essential. Protection includes safety avoiding deterministic effects and stochastic effects. To protect against both deterministic and stochastic effects, the role of the radiographer is significant. Heinrich (1980) estimates that (85%) accidents are the result of the contribution of unsafe work behavior (unsafe act). Radiation accidents reported by the United States Energy Atomic Commission from 1960-1968 were caused by operator error (68%), procedural errors (8%), equipment damage (15%), and others (9%). When viewed in detail, the operator's errors were not conducting a radiation survey (46%), not following procedures (36%), not using protective equipment (6%), human error (6%), and calculating radiation exposure errors (6%). Therefore, the radiographer must know and understand ionizing radiation, its dangers, and the application of radiation protection from the results of a survey conducted at Prof. Hospital. Dr. Margono Soekarjo Purwokerto to 22 radiographers showed that the level of understanding of ionizing radiation, the dangers, and the application of radiation protection is still low. Therefore education and training are very much needed for them. Keywords: Radiation Hazard, Radiation Protection, Radiographer Education and Training


2018 ◽  
pp. 53-63
Author(s):  
Raymond H. Thornton

Resist the temptation to gloss over this chapter—it discusses the risks and safest uses of ionizing radiation utilized by interventional radiologists during medical procedures every day. The metrics used to measure and report fluoroscopic and computed tomography (CT) doses to patients (information required to be reported by the Joint Commission) are discussed. Detrimental effects of radiation, including stochastic effects (i.e., adverse effects that may occur at any dose) and deterministic effects (which occur when a threshold has been exceeded), are reviewed, as are the data that the risk of stochastic effects is based upon. Finally, techniques that operators should practice during every procedure to minimize radiation dosage, summarized by the acronym I SAVE DOSE, are introduced and presented in detail.


2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Michael Owens ◽  
Andrea Bonisoli‐Alquati ◽  
Anders Møller ◽  
Timothy Mousseau

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