Fungicidal activity of grapefruit seed extract against the pathogenic Candida species causing oral candidiasis

Here, we report the fabrication and characterization of cellulose nanofiber (CNF)-based nanocomposite films reinforced with zinc oxide nanorods (ZnOs) and grapefruit seed extract (GSE). The CNF is isolated via a combination of chemical and physical methods, and the ZnO is prepared using a simple precipitation method. The ZnO and GSE are used as functional nanofillers to produce a CNF/ZnO/GSE film. Physical (morphology, chemical interactions, optical, mechanical, thermal stability, etc.) and functional (antimicrobial and antioxidant activities) film properties are tested. The incorporation of ZnO and GSE does not impact the crystalline structure, mechanical properties, or thermal stability of the CNF film. Nanocomposite films are highly transparent with improved ultraviolet blocking and vapor barrier properties. Moreover, the films exhibit effective antimicrobial and antioxidant actions. CNF/ZnO/GSE nanocomposite films with better quality and superior functional properties have many possibilities for active food packaging use.

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A comparison of anti-inflammatory activities of green tea and grapefruit seed extract with those of microencapsulated extracts

The Korean Journal of Nutrition ◽

10.4163/kjn.2012.45.5.443 ◽

2012 ◽

Vol 45 (5) ◽

pp. 443 ◽

Cited By ~ 3

Author(s):

Yoon Kyung Jun ◽

Myung Hwan Kim ◽

Pil Nam Seong ◽

Moon-Jeong Chang

Keyword(s):

Green Tea ◽

Seed Extract ◽

Grapefruit Seed Extract ◽

Anti Inflammatory

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Oral candidiasis-adhesion of non-albicans Candida species

Zbornik Matice srpske za prirodne nauke ◽

10.2298/zmspn0814069b ◽

2008 ◽

pp. 69-78 ◽

Cited By ~ 3

Author(s):

Marija Bokor-Bratic

Keyword(s):

Candida Albicans ◽

Candida Species ◽

Oral Candidiasis ◽

Initial Step ◽

Oral Microflora ◽

Mucosal Surfaces ◽

Buccal Epithelial Cells ◽

Mucosal Infection ◽

Denture Acrylics ◽

Candida Colonisation

Oral candidiasis is an opportunistic infection caused primarily by Candida albicans. However, in recent years, species of non-albicans Candida have been implicated more frequently in mucosal infection. Candida species usually reside as commensal organisms and are part of normal oral microflora. Determining exactly how transformation from commensal to pathogen takes place and how it can be prevented is continuous challenge for clinical doctors. Candidal adherence to mucosal surfaces is considered as a critical initial step in the pathogenesis of oral candidiasis. Acrylic dentures, acting as reservoirs, play an important role in increasing the risk from Candida colonisation. Thus, this review discusses what is currently known about the adhesion of non-albicans Candida species of oral origin to buccal epithelial cells and denture acrylics.

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Denture Stomatitis: Report of a Case with Rarely Used Treatment Modality and Review of Literature

International Healthcare Research Journal ◽

10.26440/ihrj/0405.08029 ◽

2020 ◽

Vol 4 (5) ◽

pp. 116-119

Author(s):

Parul Uppal Malhotra ◽

Neera Ohri ◽

Yagyeshwar Malhotra ◽

Anindita Mallik

Keyword(s):

Candida Albicans ◽

Candida Species ◽

Fungal Infections ◽

Bacterial Colonization ◽

Oral Candidiasis ◽

Clinical Signs ◽

Fungal Growth ◽

Dimorphic Fungus ◽

Denture Stomatitis ◽

Microbial Invasion

Candida albicans is the most common Candida species isolated from the oral cavity both in healthy and diseased. Candida albicans is a dimorphic fungus existing both in blastopore phase (yeast phase) and the hyphal or mycelial phase. Although these organisms typically colonize mucocutaneous surfaces, the latter can be portals of entry into deeper tissues when host defences are compromised. Denture stomatitis is a common form of oral candidiasis that manifests as a diffuse inflammation of the maxillary denture bearing areas & is associated with angular cheilitis. At least 70% of individuals with clinical signs of denture stomatitis exhibit fungal growth & these conditions most likely result from yeast colonization of the oral mucosa combined with Bacterial colonization. Candida species act as an endogenous infecting agent on tissue predisposed by chronic trauma to microbial invasion. At one time, oral fungal infections were rare findings in general dentist's office. They were more commonly seen in hospitalized and severely debilitated patients. However with enhanced medical and pharmaceutical technology, increasing numbers of ambulatory immunosuppressed individuals with oral fungal infections are seeking out general dentists for diagnosis and treatment of these lesions.

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