Prevalence, clinical correlates and risk factors associated with tardive dyskinesia in Chinese patients with schizophrenia

Background: The value of aspirin for primary prevention continues to be debated. Data showing whether aspirin use for primary prevention adheres to established guidelines in real world practice are sparse.Methods: A total of 13,104 patients without cardiovascular diseases (CVD) were selected from the DYS-lipidemia International Study of China, a national survey of patients with dyslipidemia in 2012. The CVD risk of the participants were calculated using the 10-year risk of Ischemic Cardiovascular Diseases model. The misuse of aspirin for primary prevention was defined as having CVD risk <10% with daily aspirin. Multivariate logistic regression models were used to explore risk factors associated with aspirin misuse.Results: The proportion of the patients categorized as low, moderate and high risk for CVD were 52.9, 21.6, and 25.4% respectively. The misuse frequency of aspirin was 31.0% (2,147/6,933) in patients with low risk. The misuse of aspirin increased with aging for both men and women. In the multivariate analysis, the independent risk factors associated with aspirin misuse were hypertension, diabetes mellitus, a family history of premature CVD, and elderly age. Level of total cholesterol is negatively associated with aspirin misuse. Patients from low level hospitals are more likely to be taking aspirin inappropriately. Results remained consistent after including 2,837 patients having 10-year risk for CVD between 10 and <20%.Conclusion: The misuse of aspirin for primary prevention is common in patients having CVD risk <10%. There are important opportunities to improve evidence-based aspirin use for the primary prevention of CVD in Chinese patients.Clinical Trial Registration:https://clinicaltrials.gov/, identifier [NCT01732952].

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The prevalence, risk factors and clinical correlates of diabetes mellitus in Chinese patients with schizophrenia

Schizophrenia Research ◽

10.1016/j.schres.2019.12.029 ◽

2020 ◽

Vol 218 ◽

pp. 262-266 ◽

Cited By ~ 1

Author(s):

Lijuan Huo ◽

Guangya Zhang ◽

Xiang-Dong Du ◽

Qiaqiufang Jia ◽

Zheng-Kang Qian ◽

...

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Chinese Patients ◽

Clinical Correlates

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Prevalence and risk factors associated with glucocorticoid-induced osteoporosis in Chinese patients with rheumatoid arthritis

Archives of Osteoporosis ◽

10.1007/s11657-017-0329-0 ◽

2017 ◽

Vol 12 (1) ◽

Cited By ~ 4

Author(s):

Can-chen Ma ◽

Sheng-qian Xu ◽

Xun Gong ◽

Ying Wu ◽

Shan Qi ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Risk Factors ◽

Chinese Patients ◽

Factors Associated

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Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus

International Journal of Endocrinology ◽

10.1155/2012/157940 ◽

2012 ◽

Vol 2012 ◽

pp. 1-8 ◽

Cited By ~ 13

Author(s):

Bin-Bin He ◽

Li Wei ◽

Yun-Juan Gu ◽

Jun-Feng Han ◽

Ming Li ◽

...

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Logistic Regression ◽

Diabetic Retinopathy ◽

Glycated Albumin ◽

Chinese Patients ◽

Related Factors ◽

C Peptide ◽

Duration Of Diabetes ◽

Factors Associated

Objective.To investigate the risk factors of DR in Chinese T2DM patients.Methods.2009 patients with T2DM were included in this cross-sectional study. All patients underwent eye examination, and the DR stage was defined by an ophthalmologist. Correlation analysis was performed to evaluate the relation between DR and clinical variables. Logistic regression models were used to assess risk for those factors associated with DR.Results.A total of 597 T2DM patients (29.7%) had DR, of which 548 (27.3%) were nonproliferative diabetic retinopathy and 49 (2.4%) were proliferative diabetic retinopathy. Positive correlations were found between DR and duration of diabetes, systolic blood pressure (SBP), diastolic blood pressure, glycated hemoglobin, glycated albumin, 24 hurinary albumin excretion, peripheral atherosclerosis (PA), diabetes nephropathy (DN), diabetic peripheral neuropathy, and anemia. Negative correlations were found between DR and C-peptide and glomerular filtration rate. Logistic regression analysis revealed that duration of diabetes, SBP, DN, anemia, PA, and C-peptide were each independent risk factors of DR.Conclusion.The duration of diabetes, SBP, DN, anemia, and PA are positively associated with DR in Chinese T2DM patients, while C-peptide is negatively associated with DR. Monitoring and evaluation of these related factors will likely contribute to the prevention and treatment of DR.

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