Parotid gland incidentalomas: A single-institution experience

The epidemiology of salivary gland tumors worldwide is not very well defined. Although many studies on this subject have been undertaken, the data are generally focused on specific topics such as parotid gland neoplasms or tumors of the major salivary glands. We conducted a study to establish the prevalence and distribution of benign and malignant neoplasms of both the major and minor salivary glands at a single institution. We reviewed 244,204 cases that had come through our pathology department from January 1994 through December 2005 and found 235 cases of a salivary gland neoplasm (0.09%). The female-to-male ratio was 1.04:1, and the mean age of the patients was 47 years. Of the 235 neoplasms, 159 (67.66%) were located in the parotid gland, 34 (14.47%) in the submandibular gland, and 42 (17.87%) in the minor salivary glands. A total of 146 tumors (62.13%) were benign and 89 (37.87%) were malignant. Pleomorphic adenoma was the most common neoplasm, occurring in 98 cases (41.70%). The most common malignancy was mucoepidermoid carcinoma, with 27 cases (11.49%). Our data demonstrate that the characteristics of salivary gland tumors in a Turkish population at a single institution are similar to those reported in the literature worldwide.

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Pathology and management of masses in the accessory parotid gland region: 24-year experience at a single institution

Journal of Cranio-Maxillofacial Surgery ◽

10.1016/j.jcms.2017.11.001 ◽

2018 ◽

Vol 46 (2) ◽

pp. 183-189 ◽

Cited By ~ 3

Author(s):

Hailong Ma ◽

Shufang Jin ◽

Zhong Du ◽

Lizhen Wang ◽

Zhiyuan Zhang ◽

...

Keyword(s):

Parotid Gland ◽

Single Institution ◽

Accessory Parotid Gland

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Acinic Cell Carcinoma of the Parotid Gland: A 15-Year Review Limited to a Single Surgeon at a Single Institution

Ear Nose & Throat Journal ◽

10.1177/014556130508400915 ◽

2005 ◽

Vol 84 (9) ◽

pp. 597-602 ◽

Cited By ~ 12

Author(s):

S. Alex Kim ◽

Robert H. Mathog

Keyword(s):

Radiation Therapy ◽

Parotid Gland ◽

Facial Nerve ◽

Cell Carcinoma ◽

Acinic Cell Carcinoma ◽

Adjuvant Radiation ◽

Single Institution ◽

Acinic Cell ◽

Total Parotidectomy

The course of acinic cell carcinoma of the parotid gland following surgical and nonsurgical interventions is variable. The objective of this study was to report our experience in treating this disease and to evaluate the factors that might be involved in the treatment of the tumor and the prognosis of the patient. To limit the contributory variables that are usually found in most studies, we included only those patients (n - 11) who had been treated by a single surgeon at a single institution from 1988 through 2003. Hospital and office records were evaluated for demographic information, signs and symptoms, treatment modalities, pathology, and outcomes. Additional follow-up data were obtained through telephone interviews. For the most part, treatment included either superficial parotidectomy or total parotidectomy with facial nerve preservation; 1 patient with coexisting adenocarcinoma underwent a more radical procedure, and 4 patients underwent adjuvant radiation therapy. The most prevalent morphologic pattern of these tumors was microcystic. Follow-up ranged from 1 year and 3 months to 10 years and 9 months (mean: 4 yr and 11 mo). During that time, we found no recurrences of acinic cell carcinoma and no evidence of metastatic disease. Therefore, we conclude that acinic cell carcinoma can be successfully treated with a superficial or total parotidectomy with sparing of the facial nerve. Radiation therapy may provide adjunctive benefit.

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Ultrastructure of the Parotid Gland of the Nine-Banded Armadillo

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100080626 ◽

1977 ◽

Vol 35 ◽

pp. 640-641

Author(s):

J. R. Ruby

Keyword(s):

Endoplasmic Reticulum ◽

Parotid Gland ◽

Periodic Acid ◽

Acinar Cells ◽

Duct System ◽

Parotid Glands ◽

Dasypus Novemcinctus ◽

Anterior Portion ◽

Periodic Acid Schiff ◽

Thin Sections

Parotid glands were obtained from five adult (four male and one female) armadillos (Dasypus novemcinctus) which were perfusion-fixed. The glands were located in a position similar to that of most mammals. They extended interiorly to the anterior portion of the submandibular gland.In the light microscope, it was noted that the acini were relatively small and stained strongly positive with the periodic acid-Schiff (PAS) and alcian blue techniques, confirming the earlier results of Shackleford (1). Based on these qualities and other structural criteria, these cells have been classified as seromucous (2). The duct system was well developed. There were numerous intercalated ducts and intralobular striated ducts. The striated duct cells contained large amounts of PAS-positive substance.Thin sections revealed that the acinar cells were pyramidal in shape and contained a basally placed, slightly flattened nucleus (Fig. 1). The rough endoplasmic reticulum was also at the base of the cell.

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Ultrastructure of myoepithelial cell in parotid gland

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100103772 ◽

1988 ◽

Vol 46 ◽

pp. 342-343

Author(s):

C. N. Sun

Keyword(s):

Parotid Gland ◽

Osmium Tetroxide ◽

Individual Cell ◽

Branching Processes ◽

Muscle Cells ◽

Myoepithelial Cells ◽

Uranyl Acetate ◽

Thin Sections ◽

Gland Carcinoma ◽

Parotid Gland Carcinoma

Myoepithelial cells have been observed in the prostate, harderian, apocrine, exocrine sweat and mammary glands. Such cells and their numerous branching processes form basket-like structures around the glandular acini. Their shapes are quite different from structures seen either in spindleshaped smooth muscle cells or skeletal muscle cells. These myoepithelial cells lie on the epithelial side of the basement membrane in the glands. This presentation describes the ultrastructure of such myoepithelial cells which have been found also in the parotid gland carcinoma from a 45-year old patient.Specimens were cut into small pieces about 1 mm3 and immediately fixed in 4 percent glutaraldehyde in phosphate buffer for two hours, then post-fixed in 1 percent buffered osmium tetroxide for 1 hour. After dehydration, tissues were embedded in Epon 812. Thin sections were stained with uranyl acetate and lead citrate. Ultrastructurally, the pattern of each individual cell showed wide variations.

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