1H NMR based metabolomic profiling of early life stage zebrafish (Danio rerio) exposed to a water-soluble fraction of weathered sediment-bound diluted bitumen

2021 ◽  
Vol 232 ◽  
pp. 105766
Author(s):  
Kaden K. Fujita ◽  
Zhe Xia ◽  
Gregg Tomy ◽  
Tony Montina ◽  
Steve Wiseman
2019 ◽  
Vol 54 (5) ◽  
pp. 2869-2877 ◽  
Author(s):  
Wenhui Qiu ◽  
Bei Chen ◽  
Justin B. Greer ◽  
Jason T. Magnuson ◽  
Ying Xiong ◽  
...  

2007 ◽  
Vol 23 (9) ◽  
pp. 529-536 ◽  
Author(s):  
T Şişman ◽  
F Geyikoğlu ◽  
M Atamanalp

Polychlorinated biphenyls are a widespread aquatic contaminant. In this article, specific polychlorinated biphenyl congeners were examined for embryo and early life-stage toxicity in zebrafish ( Danio rerio). A set of three polychlorinated biphenyl congeners (non-ortho polychlorinated biphenyl 126, mono-ortho polychlorinated biphenyl 28 and di-ortho polychlorinated biphenyl 153) were tested. The typical lesions observed were yolk sac edema, vertebra defect, craniofacial malformations (double head, triple retina), anaxial body and inhibition of swim bladder inflation. Moreover, embryo and larval mortality increased and hatching success decreased. The severity of abnormalities and mortalities were concentration- and congener-dependent. Of the compounds tested, polychlorinated biphenyl congener 126 was found to be highly toxic to the fish embryos following exposure. The Lethal Concentration 50 values for polychlorinated biphenyl 28, polychlorinated biphenyl 126, polychlorinated biphenyl 153 calculated by probit analysis were 3.270, 1.298 and 5.375 ppm, respectively. The inhibition of swim bladder inflation was the most sensitive endpoint measured, and it is suggested that the inhibition of swim bladder inflation may be mediated by mechanism with an aryl hydrocarbon receptor activation.


2016 ◽  
Vol 218 ◽  
pp. 605-614 ◽  
Author(s):  
Jasmine Nahrgang ◽  
Paul Dubourg ◽  
Marianne Frantzen ◽  
Daniela Storch ◽  
Flemming Dahlke ◽  
...  

Author(s):  
Liselotte Westerlund ◽  
Karin Billsson ◽  
Patrik L. Andersson ◽  
Mats Tysklind ◽  
Per-Erik Olsson

2002 ◽  
Vol 120 (2) ◽  
pp. 355-362 ◽  
Author(s):  
Erwin W.M Roex ◽  
Erik de Vries ◽  
Cornelis A.M van Gestel

2018 ◽  
Vol 610-611 ◽  
pp. 972-982 ◽  
Author(s):  
Sébastien Cambier ◽  
Marthe Røgeberg ◽  
Anastasia Georgantzopoulou ◽  
Tommaso Serchi ◽  
Camilla Karlsson ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document