Chronic exposure to sublethal concentrations of saxitoxin reduces antioxidant activity and immunity in zebrafish but does not affect reproductive parameters

2021 ◽  
pp. 106070
Author(s):  
Md. Niamul Haque ◽  
Sang-Eun Nam ◽  
Young-Seok Han ◽  
Hyoung Sook Park ◽  
Jae-Sung Rhee
Keyword(s):  
Antioxidant Activity ◽  
Chronic Exposure ◽  
Reproductive Parameters ◽  
Sublethal Concentrations

SOME IMMUNOBIOCHEMICAL INDICES IN CARASSIUS CARASSIUS EXPOSED TO SUBLETHAL CONCENTRATIONS OF ZINK IONS

2017 ◽  
pp. 50-53
Author(s):  
N. I. Silkina ◽  
D. V. Mikryakov ◽  
V. R. Mikryakov
Keyword(s):  
Antioxidant Activity ◽  
Blood Serum ◽  
Immune Complexes ◽  
Chronic Exposure ◽  
Antimicrobial Properties ◽  
Carassius Carassius ◽  
Experimental Conditions ◽  
Sublethal Concentrations

Investigation results are reported on immunobiochemical indices in carassius carassius at a chronic exposure to sub-lethal Zink ions concentrations. In blood serum and liver, the following characteristics were investigated: antimicrobial properties, proportion of immune- deficient animals, content of non specific immune complexes, common lipids level, content of lipids peroxidation products and antioxidant activity. The relation between magnitudes of indices under investigation in fishes and the duration of their presence under experimental conditions is shown.

scholarly journals Alteration of Blood Parameters and Histoarchitecture of Liver and Kidney of Silver Barb after Chronic Exposure to Quinalphos

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Golam Mohammod Mostakim ◽  
Md. Mahiuddin Zahangir ◽  
Mahbuba Monir Mishu ◽  
Md. Khalilur Rahman ◽  
M. Sadiqul Islam
Keyword(s):  
Chronic Exposure ◽  
White Blood Cells ◽  
Blood Parameters ◽  
Mean Corpuscular Hemoglobin ◽  
Central Vein ◽  
Hematopoietic Tissue ◽  
Corpuscular Hemoglobin ◽  
Liver And Kidney ◽  
Sublethal Concentrations ◽  
Silver Barb

Quinalphos (QP) is commonly used for pest control in the agricultural fields surrounding freshwater reservoirs. This study was conducted to evaluate the chronic toxicity of this pesticide on blood parameters and some organs of silver barb,Barbonymus gonionotus. Fish were exposed to two sublethal concentrations, 0.47 ppm and 0.94 ppm, of QP for a period of 28 days. All the blood parameters (red blood cell, hematocrit, and hemoglobin) and blood glucose except for white blood cells decreased with increasing concentration of toxicant and become significantly lower (p<0.05) at higher concentration when compared with control. The derived hematological indices of mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration were equally altered compared to control. Histoarchitectural changes of liver and kidney were observed after exposure to the QP. Hypertrophy of hepatocytes, mild to severe necrosis, ruptured central vein, and vacuolation were observed in the liver of treated groups. Highly degenerated kidney tubules and hematopoietic tissue, degeneration of renal corpuscle, vacuolization, and necrosis were evident in the kidney of treated groups. In conclusion, chronic exposure to QP at sublethal concentrations induced hematological and histological alterations in silver barb and offers a simple tool to evaluate toxicity derived alterations.

ALTERATIONS IN THE ORGANIC RESERVE OF ZINC EXPOSED FRESH WATER CATFISH, CLARIAS BATRACHUS

2018 ◽  
Vol 24 (2) ◽  
Author(s):  
NAVNEET KUNWER SRIVASTAVA ◽  
SADGURU PRAKASH
Keyword(s):  
Fresh Water ◽  
Chronic Exposure ◽  
Zinc Sulphate ◽  
Clarias Batrachus ◽  
Lethal Concentration ◽  
Total Lipids ◽  
Total Proteins ◽  
Kidney Liver ◽  
Sublethal Concentrations ◽  
Zinc Exposure

Present study was carried out to evaluate the changes in organic reserves of kidney, liver, gill and muscles of Clarias batrachus exposed to sublethal concentrations of zinc sulphate in water for a period of 15,30 and 45 days. Four groups of twenty five fish were subjected to 0 (control), 10, 20 and 30 mg/L of zinc sulphate. The sub-chronic exposure of Clarias batrachus to sub-lethal concentration of Zinc sulphate showed a decline in glycogen, total proteins, cholesterol and total lipids in all these tissues. The levels of these organic reserves alter simultaneously with an increase in dose and duration of zinc exposure.

scholarly journals Transgenerational effects in DNA methylation, genotoxicity and reproductive phenotype by chronic arsenic exposure

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lydia Enith Nava-Rivera ◽  
Nadia Denys Betancourt-Martínez ◽  
Rodrigo Lozoya-Martínez ◽  
Pilar Carranza-Rosales ◽  
Nancy Elena Guzmán-Delgado ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Early Life ◽  
Chronic Exposure ◽  
Sperm Quality ◽  
Arsenic Exposure ◽  
Environmental Toxicants ◽  
Reproductive Parameters ◽  
Transgenerational Effects ◽  
Chronic Arsenic Exposure ◽  
Reproductive Phenotype

AbstractAn emerging concern is the influences of early life exposure to environmental toxicants on offspring characteristics in later life. Since recent evidence suggests a transgenerational transference of aberrant phenotypes from exposed-parents to non-exposed offspring related to adult-onset diseases including reproductive phenotype. The transgenerational potential of arsenic a well know genotoxic and epigenetic modifier agent has not been assessed in mammals until now. In this experimental study, we evaluated the transgenerational effects of arsenic in a rat model with chronic exposure to arsenic. Rats chronically exposed to arsenic in drinking water (1 mg As2O3/mL) (F0) were mated to produce the arsenic lineage (F1, F2, and F3). The arsenic toxic effects on were evaluated over the four generations by analyzing the DNA methylation percentage, genotoxicity in WBC and physical and reproductive parameters, including sperm quality parameters and histopathological evaluation of the gonads. Chronic exposure to arsenic caused genotoxic damage (F0–F3) different methylation patterns, alterations in physical and reproductive parameters, aberrant morphology in the ovaries (F0 and F1) and testicles (F1–F3), and a decrease in the quality of sperm (F0–F3, except F2). Parental chronic arsenic exposure causes transgenerational genotoxicity and changes in global DNA methylation which might be associated with reproductive defects in rats. Combined with recent studies reveal that disturbances in the early life of an individual can affect the health of later generations.

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