Life extension after heat shock exposure: Assessing meta-analytic evidence for hormesis

2013 ◽  
Vol 12 (2) ◽  
pp. 653-660 ◽  
Author(s):  
Malgorzata Lagisz ◽  
Katie L. Hector ◽  
Shinichi Nakagawa
2009 ◽  
Vol 407 (7) ◽  
pp. 2411-2419 ◽  
Author(s):  
Shu-jun Xu ◽  
Chun-jiang Liu ◽  
Ping-an Jiang ◽  
Wei-min Cai ◽  
Yan Wang

2015 ◽  
Vol 5 (5) ◽  
pp. 72-80 ◽  
Author(s):  
S Yu Funikov ◽  
SS Ryazansky ◽  
ES Zelentsova ◽  
VI Popenko ◽  
OG Leonova ◽  
...  
Keyword(s):  

2000 ◽  
Vol 23 (2) ◽  
pp. 301-304 ◽  
Author(s):  
Maria Luiza S. Mello ◽  
Sílvya S. Maria ◽  
Maria Cristina H. Tavares

The survival of Triatoma infestans and of somatic cells from this species is affected by heat shock. In this study, we examined the cell death responses of male germ line cells from 5th instar nymphs 7 and 30 days after heat shock exposure (40ºC, 1 h). The preparations were stained by the Feulgen reaction and the TUNEL immunocytochemical assay. Apoptosis was elicited by heat shock, with positive TUNEL responses in spermatogonial chromatin and chromosomes, spermatids and sperm cells. Spermatogonia were most affected seven days after the shock whereas some spermatids and sperm cells exhibited DNA fragmentation only thirty days after heat shock. The rate of cell death varied among the cells. In some cases, cellular differentiation was unaffected by heat shock, with DNA fragmentation occurring towards the end of spermatogenesis.


Author(s):  
Courtney Carroll Alexander ◽  
Erin Munkáscy ◽  
Haven Tillmon ◽  
Tamara Fraker ◽  
Jessica Scheirer ◽  
...  

Abstract To explore the role of the small heat shock protein beta 1 (HspB1, also known as Hsp25 in rodents and Hsp27 in humans) in longevity, we created a Caenorhabiditis elegans model with a high level of ubiquitous expression of the naked mole-rat HspB1 protein. The worms showed increased lifespan under multiple conditions and also increased resistance to heat stress. RNAi experiments suggest that HspB1-induced life extension is dependent on the transcription factors skn-1 (Nrf2) and hsf-1 (Hsf1). RNAseq from HspB1 worms showed an enrichment in several skn-1 target genes, including collagen proteins and lysosomal genes. Expression of HspB1 also improved functional outcomes regulated by SKN-1, specifically oxidative stress resistance and pharyngeal integrity. This work is the first to link a small heat shock protein with collagen function, suggesting a novel role for HspB1 as a hub between canonical heat response signaling and SKN-1 transcription.


2019 ◽  
Vol 9 (2) ◽  
pp. 90-101
Author(s):  
Osama Galal Sakr ◽  
Baliegh Hamdy Mousa ◽  
Khamis Refaay Said Emam ◽  
Ali Saber Morsy ◽  
Nagwa Abd El-Hady Ahmed

Revista CERES ◽  
2014 ◽  
Vol 61 (3) ◽  
pp. 306-312
Author(s):  
Sidiane Coltro ◽  
Laline Broetto ◽  
Maria Cristina Copelo Rotilli ◽  
Alice Jacobus de Moraes ◽  
Fabiane Karine Barp ◽  
...  

Heat shock and salicylic acid have been studied on shelf-life extension of fruits. The benefits of these techniques have been related to their effect on inducing physiological defense responses against the oxidative stress and pathogen development. The objective of this study was to evaluate the effect of heat shock and salicylic acid on the postharvest preservation and contents of total phenolics, anthocyanins, ascorbic acid, fresh weight loss and microbiological quality of organic strawberries cv. Dover. Strawberries produced organically and stored at 5 ºC were subjected to heat shock (45 ºC ± 3 ºC for 3 h), application of salicylic acid (soaking in 2.0 mmol L-1 solution), heat shock in combination with salicylic acid and control. After treatment, the fruits were packed and stored in a climatic chamber at 5 ºC ± 2 ºC. At 1, 7 and 14 days, the experimental units were removed from refrigeration and kept at room temperature of approximately 20 ºC for two days. There was no effect of treatments on fresh weight loss, incidence of pathogens or chemical variations in strawberry fruits during the storage period. In natural conditions, organically grown strawberries remained in good condition for sale up to seven days of storage in all treatments.


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