Ileus following total hip or knee arthroplasty is associated with increased risk of deep venous thrombosis and pulmonary embolism

2004 ◽  
Vol 19 (7) ◽  
pp. 82-86 ◽  
Author(s):  
Keith R. Berend ◽  
Adolph V. Lombardi ◽  
Thomas H. Mallory ◽  
Kathleen L. Dodds ◽  
Joanne B. Adams
2002 ◽  
Vol 96 (5) ◽  
pp. 1140-1146 ◽  
Author(s):  
Margaret Wood ◽  
Carlos B. Mantilla ◽  
Terese T. Horlocker ◽  
Darrell R. Schroeder ◽  
Daniel J. Berry ◽  
...  

Background There is limited information about the frequency of perioperative complications after elective primary orthopedic total hip and knee arthroplasty in contemporary practice. The purpose of this study was to determine the frequency of clinically relevant myocardial infarction, pulmonary embolism, deep venous thrombosis, and death within 30 days after elective primary hip or knee arthroplasty treated according to contemporary perioperative management. Methods The authors examined the medical records of consecutive patients undergoing hip or knee arthroplasty at their institution in a 10-yr period. Prospectively collected databases were used to identify patients with the diagnosis of myocardial infarction, pulmonary embolism, deep venous thrombosis, or death using strict validation criteria and diagnostic-certainty categories. Results A total of 10,244 patients underwent primary total hip or knee arthroplasty in the period of study. Of these, 224 patients had one or more adverse events (overall event rate: 2.2%; myocardial infarction: 0.4%; pulmonary embolism: 0.7%; deep venous thrombosis: 1.5%; death: 0.5%). Most adverse events (myocardial infarction, pulmonary embolism, and death) increased in frequency with older age, particularly for patients aged 70 yr or older. Myocardial infarction occurred more frequently in male patients. There were no differences in the overall event frequency between types of procedure. However, pulmonary embolism was highest in patients undergoing bilateral knee operations. Conclusions The overall frequency of serious complications within 30 days after primary total hip or knee arthroplasty with contemporary practice was 2.2%. Accurate knowledge of the perioperative risks associated with widely performed elective operations can be used to implement management strategies that may further improve patient outcomes and decrease cost.


2003 ◽  
Vol 18 (2) ◽  
pp. 174-179 ◽  
Author(s):  
P.S. Ko ◽  
W.F. Chan ◽  
T.H. Siu ◽  
J. Khoo ◽  
W.C. Wu ◽  
...  

2000 ◽  
Vol 375 ◽  
pp. 168-174 ◽  
Author(s):  
Satoru Fujita ◽  
Shigeaki Hirota ◽  
Takenori Oda ◽  
Yasuji Kato ◽  
Yasunori Tsukamoto ◽  
...  

2017 ◽  
Vol 49 (2) ◽  
pp. 1601014 ◽  
Author(s):  
Bengt Zöller ◽  
Mirnabi Pirouzifard ◽  
Ashfaque A. Memon ◽  
Jan Sundquist ◽  
Kristina Sundquist

Asthma is associated with an increased risk of pulmonary embolism (PE) but little is known about whether asthma is associated with an increased risk of deep venous thrombosis (DVT). The aim in this study was to determine the risk of the first event of PE, DVT or a combination of PE and DVT in patients with asthma.We conducted this nationwide case–control study using data from Swedish nationwide registries. We included 114 366 Swedish-born patients with a first hospital diagnosis of PE, 76 494 patients with DVT and 6854 patients with both PE and DVT in Sweden between 1981 and 2010. We also included five age-, sex- and education-matched population controls. All previous hospital diagnoses of asthma were identified. Conditional logistic regression was used to compute odds ratios with adjustment for potential confounders.Asthma was associated with an adjusted odds ratio for PE of 1.43 (95% CI 1.37–1.50), for DVT of 1.56 (95% CI 1.47–1.65) and for combined PE and DVT of 1.60 (95% CI 1.32–1.93). Asthma was associated with an increased risk of PE, DVT and combined PE and DVT.Thus, the inflammation conferred by asthma seems to have systemic (and not just local) prothrombotic effects with increased risk of both DVT and PE.


2015 ◽  
Vol 110 ◽  
pp. S554
Author(s):  
Sanjay Bhandari ◽  
Muhammad Shahreyar ◽  
Mashooque Ali Dahar ◽  
Ahmad Hanif ◽  
Thangam Venkatesan ◽  
...  

2004 ◽  
Vol 91 (04) ◽  
pp. 725-732 ◽  
Author(s):  
Tomosue Takada ◽  
Shigehito Sato ◽  
Mutsuhito Kikura

SummaryWe investigated age- and sex-specific incidence, risk factors, and latency period of a perioperative acute thromboembolism syndrome (PATS) in a large cohort study. We prospectively analyzed data on 21903 consecutive surgery patients to determine the incidence of myocardial infarction, pulmonary embolism, deep venous thrombosis, stroke, and cardiovascular death within 30 postoperative days. Among 255 (1.2 percent) patients with thromboembolism, 105 (0.48 percent) suffered myocardial infarction (mean latency: 5 days), 30 (0.14 percent) suffered pulmonary embolism (6 days), 23 (0.11 percent) suffered deep venous thrombosis (10 days), 97 (0.44 percent) suffered stroke (11 days), and 13 (0.06 percent) died (12 days). The critical period was postoperative week 1 for myocardial infarction and pulmonary embolism, and postoperative week 1 and 2 for deep venous thrombosis, stroke, and death. Risk of all events increased with age (P<0.0001), particularly for over 70 years (odds ratio: 12.5; 95 percent confidence interval, 7.8 to 19.9). Males had an increased risk (P<0.0001) of myocardial infarction (odds ratio; 1.5; 95 percent confidence interval, 1.0 to 2.3). Females had an increased risk (P<0.0001) of pulmonary embolism (odds ratio: 2.7; 95 percent confidence interval, 1.3 to 5.9) and deep venous thrombosis (odds ratio: 9.8; 95 percent confidence interval, 3.3 to 29.3). Risk of thromboembolic event was higher (P<0.0001) in patients with a history of arterial thrombotic events or cancer. Trend analysis indicates that thromboembolic events will increase 3-fold over the next decade. Our findings enable identification of higher risk patients for prophylactic anti-thromboembolic treatment and awareness of the critical postoperative period.


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