Preoperative Treatment of Hepatitis C Is Associated With Lower Prosthetic Joint Infection Rates in US Veterans

2019 ◽  
Vol 34 (7) ◽  
pp. S319-S326.e1 ◽  
Author(s):  
Ilya Bendich ◽  
Steven Takemoto ◽  
Joseph T. Patterson ◽  
Alexander Monto ◽  
Thomas C. Barber ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Prosthetic Joint Infection ◽  
Joint Infection ◽  
Preoperative Treatment ◽  
Infection Rates ◽  
Prosthetic Joint ◽  
Us Veterans

scholarly journals Extended Antibiotic Prophylaxis May Be Linked to Lower Peri-prosthetic Joint Infection Rates in High-Risk Patients: An Evidence-Based Review

2019 ◽  
Vol 15 (3) ◽  
pp. 297-301 ◽  
Author(s):  
Christopher J. DeFrancesco ◽  
Michael C. Fu ◽  
Cynthia A. Kahlenberg ◽  
Andy O. Miller ◽  
Mathias P. Bostrom
Keyword(s):  
High Risk ◽  
Antibiotic Prophylaxis ◽  
Prosthetic Joint Infection ◽  
Joint Infection ◽  
Evidence Based ◽  
Infection Rates ◽  
High Risk Patients ◽  
Prosthetic Joint ◽  
Risk Patients

scholarly journals Body mass and weight thresholds for increased prosthetic joint infection rates after primary total joint arthroplasty

2016 ◽  
Vol 87 (2) ◽  
pp. 132-138 ◽  
Author(s):  
Anne Lübbeke ◽  
Matthieu Zingg ◽  
Diemlan Vu ◽  
Hermes H Miozzari ◽  
Panayiotis Christofilopoulos ◽  
...  
Keyword(s):  
Body Mass ◽  
Prosthetic Joint Infection ◽  
Total Joint Arthroplasty ◽  
Joint Infection ◽  
Joint Arthroplasty ◽  
Infection Rates ◽  
Prosthetic Joint

scholarly journals Successful Treatment of Staphylococcus aureus Prosthetic Joint Infection with Bacteriophage Therapy

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1182
Author(s):  
Claudia Ramirez-Sanchez ◽  
Francis Gonzales ◽  
Maureen Buckley ◽  
Biswajit Biswas ◽  
Matthew Henry ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Prosthetic Joint Infection ◽  
Joint Infection ◽  
Multidrug Resistant ◽  
Successful Outcome ◽  
Prolonged Treatment ◽  
Lytic Phage ◽  
Bacteriophage Therapy ◽  
Prosthetic Joint ◽  
Knee Joint Infection

Successful joint replacement is a life-enhancing procedure with significant growth in the past decade. Prosthetic joint infection occurs rarely; it is a biofilm-based infection that is poorly responsive to antibiotic alone. Recent interest in bacteriophage therapy has made it possible to treat some biofilm-based infections, as well as those caused by multidrug-resistant pathogens, successfully when conventional antibiotic therapy has failed. Here, we describe the case of a 61-year-old woman who was successfully treated after a second cycle of bacteriophage therapy administered at the time of a two-stage exchange procedure for a persistent methicillin-sensitive Staphylococcus aureus (MSSA) prosthetic knee-joint infection. We highlight the safety and efficacy of both intravenous and intra-articular infusions of bacteriophage therapy, a successful outcome with a single lytic phage, and the development of serum neutralization with prolonged treatment.

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