Carotid atherosclerosis in a very elderly population: Role of ageing and other cardiovascular risk factors

Background This study examines changes in the ideal cardiovascular health (CVH) status and whether these changes are associated with incident cardiovascular disease (CVD) and mortality in the elderly Asian population. Methods and Results In the Korea National Health Insurance Service–Senior cohort aged ≥60 years, 208 673 participants without prior CVD, including 109 431 who showed changes in CVH status, were assessed. The association of the changes in cardiovascular risk factors with incident CVD was assessed from 2004 to 2014 in the elderly (aged 60–74 years) and very elderly (≥75 years) groups. During the follow‐up period (7.1 years for CVD and 7.2 years for mortality), 19 429 incident CVD events and 24 225 deaths occurred. In both the elderly and very elderly participants, higher CVH status resulted in a lower risk of CVD and mortality. In the very elderly participants, compared with consistently low CVH, consistently high CVH (subhazard ratio, 0.41; 95% CI, 0.23–0.73) was associated with a lower risk of CVD. This trend was consistently observed in the elderly population. In the very elderly participants, total cholesterol level was not informative enough for the prediction of CVD events. In both the elderly and very elderly groups, body mass index and total cholesterol were not informative enough for the prediction of all‐cause mortality. Conclusions In both the elderly and very elderly Asian populations without CVD, a consistent relationship was observed between the improvement of a composite metric of CVH and the reduced risk of CVD. Body mass index and total cholesterol were not informative enough for the prediction of all‐cause mortality in both the elderly and very elderly groups.

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Association of tobacco and alcohol consumption with cardiovascular risk factors among elderly population in India

Journal of Family Medicine and Primary Care ◽

10.4103/jfmpc.jfmpc_628_20 ◽

2020 ◽

Vol 9 (10) ◽

pp. 5242

Author(s):

Umesh Kapil ◽

Aakriti Gupta ◽

Ravi Belwal ◽

Lakshmy Ramakrishnan ◽

Preetika Khenduja

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Alcohol Consumption ◽

Cardiovascular Risk Factors ◽

Elderly Population

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Relationship between serum leptin levels, non-cardiovascular risk factors and mortality in hemodialysis patients

Romanian Journal of Internal Medicine ◽

10.2478/rjim-2021-0002 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Ivona Risovic ◽

Vlastimir Vlatkovic ◽

Snjezana Popovicpejicic ◽

Gabrijela Malešević

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Survival Rates ◽

Inverse Correlation ◽

Study Groups ◽

Mineral And Bone Disorder ◽

Serum Leptin ◽

Significant Difference

Abstract Introduction. Hemodialysis (HD) patients have higher mortality rate than the general population. Recent studies indicate a significant role of non-cardiovascular risk factors in for mortality in HD patients. Leptin is protein hormone and may indicate malnutrition in HD patients. Its role in mortality in these patients is being examined. This study aimed to investigate the correlation between serum leptin levels and non-cardiovascular risk factors and relationship between leptin level and mortality in HD patients. Methods The prospective study included 93 patients on maintenance HD and follow-up period was 12 months. We measured leptin level and evaluated non-cardiovascular risk factors: nutritional status, anemia, volemia, parameters of mineral and bone disorder. Results. Out of 93 patients 9 died during study and 1 underwent kidney transplantation. Malnutrition and hypervolemia were two main non-cardiovascular risk factors among deceased subjects. Leptin showed a significant direct correlation with nutritional BMI (r = 0.72, P <0.001), fat tissue index (r = 0.74, P <0.001) and statistically significant inverse correlation with leantissue index (r = -0.349, P <0.05) and inverse correlation with volemic parameters (overhydration / extracellular water ratio (r = -0.38, P <0.001), but no association with anemia and mineral bone parameters was observed. Elevated leptin levels were associated with better survival. However, no statistically significant difference in survival rates was observed between the study groups (Log-Rank P =0.214, Breslow P =0.211, Tarone-Ware P=0.212). Conclusion: Deceased patients had significantly lower leptin values. Leptin was associated with two non-cardiovascular risk factors for mortality: malnutrition and hypervolemia.

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Role of green tea in reduction of cardiovascular risk factors

Nutrition and Dietary Supplements ◽

10.2147/nds.s6025 ◽

2010 ◽

pp. 85

Author(s):

Charalambos Vlachopoulos ◽

Alexopoulos ◽

Stefanadis

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Green Tea

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Cardiovascular Risk Factors: Role of Lifestyle

Handbook of Psychocardiology ◽

10.1007/978-981-287-206-7_6 ◽

2016 ◽

pp. 65-77

Author(s):

Gautam Vaddadi

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors

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Uric acid and uric acid/creatinine ratio and their correlations with the hemorheological determinants in subjects with subclinical carotid atherosclerosis

Clinical Hemorheology and Microcirculation ◽

10.3233/ch-211322 ◽

2022 ◽

pp. 1-9

Author(s):

Gregorio Caimi ◽

Caterina Urso ◽

Salvatore Brucculeri ◽

Corrado Amato ◽

Rosalia Lo Presti ◽

...

Keyword(s):

Risk Factors ◽

Insulin Resistance ◽

Uric Acid ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Serum Uric Acid ◽

Carotid Atherosclerosis ◽

Erythrocyte Aggregation ◽

Creatinine Ratio ◽

Serum Uric Acid Concentration

BACKGROUND AND OBJECTIVE: we have examined the concentration of serum uric acid and the serum uric acid/creatinine ratio as well as their correlations with the main determinants of the hemorheological profile in a group of subjects with subclinical carotid atherosclerosis. METHODS: we evaluated the concentration of serum uric acid and the serum uric acid/creatine ratio in 43 men and 57 women [median age 66.00 (25)] with subclinical carotid atherosclerosis, subsequently divided according to the number of traditional cardiovascular risk factors and to the insulin resistance degree. RESULTS: serum uric acid, but not the serum uric acid/creatinine ratio, results strongly influenced by the number of cardiovascular risk factors and by the insulin resistance degree. In the whole group and in the subgroups of subclinical carotid atherosclerosis subjects, serum uric acid and serum uric acid/creatinine ratio show significant correlation, besides with whole blood viscosity, with plasma viscosity and erythrocyte aggregation. The influence of the serum uric acid on the erythrocyte aggregability that is a part of the erythrocyte aggregation is to ascribe to the action carried out by serum uric acid on the erythrocyte zeta potential. CONCLUSIONS: it is reasonable to think that the treatment of the asymptomatic or symptomatic hyperuricemia with the urate-lowering therapy that reduces the serum uric acid concentration may reflect on the hemorheological profile which role on the atherosclerotic cardiovascular disease is well known.

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Prevalence of Cardiovascular Risk Factors in the Elderly Population of Alentejo

Handbook of Research on Health Systems and Organizations for an Aging Society - Advances in Human Services and Public Health ◽

10.4018/978-1-5225-9818-3.ch014 ◽

2020 ◽

pp. 185-195

Author(s):

Maria do Céu Mendes Pinto Marques ◽

Ana Filipa Pereira Vaz ◽

Ana Sofia Emídio Cardoso Leite ◽

Cláudia Sofia Araújo ◽

Cláudia Roque Condeço ◽

...

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Elderly Population ◽

Research Question ◽

National Level ◽

The Elderly ◽

Regional Level ◽

Age Group ◽

Prevalence Studies

The objective of this chapter is to identify cardiovascular risk factors in the elderly and their prevalence in the elderly population of Alentejo. The research question was elaborated according to the PI[C]OD methodology. The prevalence studies included allow the authors to identify the risk factors with the greatest impact on cardiovascular diseases, with the analysis of at least one of the factors (hypertension, diabetes, smoking, obesity, hypercholesterolemia, alcoholism, and sedentary lifestyle) and their prevalence in the elderly from the region of Alentejo. The results present the prevalence of cardiovascular risk factors, mainly at the national level, compared to those at the regional level, with a small number of exclusive studies in the Alentejo region, while simultaneously disaggregating the results by age group. From the data obtained, it can be concluded that the prevalence of risk factors is generally increased in the elderly population and, consequently, in Alentejo, because it is a region in the interior of the country that is predominantly rural and very old.

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