Improving speech perception in noise in young and older adults using transcranial magnetic stimulation

2021 ◽  
Vol 222 ◽  
pp. 105009
Author(s):  
Valérie Brisson ◽  
Pascale Tremblay
Keyword(s):  
Older Adults ◽  
Speech Perception ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Speech Perception In Noise

Individuals With Mild Cognitive Impairment and Alzheimer's Disease Benefit From Audiovisual Speech Cues and Supportive Sentence Context

2021 ◽  
pp. 1-10
Author(s):  
Alexandre Chauvin ◽  
Shari Baum ◽  
Natalie A. Phillips
Keyword(s):  
Alzheimer’S Disease ◽  
Older Adults ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Speech Perception ◽  
Sentence Context ◽  
Speech Perception In Noise ◽  
Healthy Older Adults ◽  
Speech Cues

Purpose Speech perception in noise becomes difficult with age but can be facilitated by audiovisual (AV) speech cues and sentence context in healthy older adults. However, individuals with Alzheimer's disease (AD) may present with deficits in AV integration, potentially limiting the extent to which they can benefit from AV cues. This study investigated the benefit of these cues in individuals with mild cognitive impairment (MCI), individuals with AD, and healthy older adult controls. Method This study compared auditory-only and AV speech perception of sentences presented in noise. These sentences had one of two levels of context: high (e.g., “Stir your coffee with a spoon”) and low (e.g., “Bob didn't think about the spoon”). Fourteen older controls ( M age = 72.71 years, SD = 9.39), 13 individuals with MCI ( M age = 79.92 years, SD = 5.52), and nine individuals with probable Alzheimer's-type dementia ( M age = 79.38 years, SD = 3.40) completed the speech perception task and were asked to repeat the terminal word of each sentence. Results All three groups benefited (i.e., identified more terminal words) from AV and sentence context. Individuals with MCI showed a smaller AV benefit compared to controls in low-context conditions, suggesting difficulties with AV integration. Individuals with AD showed a smaller benefit in high-context conditions compared to controls, indicating difficulties with AV integration and context use in AD. Conclusions Individuals with MCI and individuals with AD do benefit from AV speech and semantic context during speech perception in noise (albeit to a lower extent than healthy older adults). This suggests that engaging in face-to-face communication and providing ample context will likely foster more effective communication between patients and caregivers, professionals, and loved ones.

Cortico – (thalamo) – cortical interactions, gamma resonance, and auditory hallucinations in schizophrenia

2004 ◽  
Vol 27 (6) ◽  
pp. 797-798 ◽  
Author(s):  
Ralph E. Hoffman ◽  
Daniel H. Mathalon ◽  
Judith M. Ford ◽  
John H. Krystal
Keyword(s):  
Speech Perception ◽  
Transcranial Magnetic Stimulation ◽  
Speech Processing ◽  
Magnetic Stimulation ◽  
Corollary Discharge ◽  
Auditory Hallucinations ◽  
Behavioral Studies ◽  
Verbal Thought

Transcranial magnetic stimulation, EEG, and behavioral studies by our group implicate spurious activation of speech perception neurocircuitry in the genesis of auditory hallucinations in schizophrenia. The neurobiological basis of these abnormalities remains uncertain, however. We review our ongoing studies, which suggest that altered cortical coupling underlies speech processing in schizophrenia and is expressed via disrupted gamma resonances and impaired corollary discharge function of self-generated verbal thought.

Medial Olivocochlear Functioning and Speech Perception in Noise in Older Adults

2008 ◽  
Vol 13 (5) ◽  
pp. 328-334 ◽  
Author(s):  
Siti Zamratol-Mai Sarah Mukari ◽  
Wan Hasyimah Wan Mamat
Keyword(s):  
Older Adults ◽  
Speech Perception ◽  
Speech Perception In Noise ◽  
Medial Olivocochlear

scholarly journals Speech Perception in Noise Is Associated With Different Cognitive Abilities in Chinese-Speaking Older Adults With and Without Hearing Aids

2022 ◽  
Vol 12 ◽  
Author(s):  
Yuan Chen ◽  
Lena L. N. Wong ◽  
Shaina Shing Chan ◽  
Joannie Yu
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Executive Function ◽  
Speech Perception ◽  
Cognitive Function ◽  
Verbal Learning ◽  
Chinese Adults ◽  
Speech Perception In Noise ◽  
Older Chinese ◽  
Older Chinese Adults

Chinese-speaking older adults usually do not perceive a hearing problem until audiometric thresholds exceed 45 dB HL, and the audiometric thresholds of the average hearing-aid (HA) user often exceed 60 dB HL. The purpose of this study was to examine the relationships between cognitive and hearing functions (measured as audiometric or speech reception thresholds) in older Chinese adults with HAs and with untreated hearing loss (HL). Participants were 49 Chinese older adults who used HAs and had moderate to severe HL (HA group), and 46 older Chinese who had mild to moderately severe HL but did not use HAs (untreated; or UT group). Multiple linear regression analysis was employed to evaluate how well age, education level, audiometric thresholds, and speech perception in noise were related to performance on general cognitive function, working memory, executive function, attention, and verbal learning tests. Results showed that speech perception in noise alone accounted for 13–25% of the variance in general cognitive function, working memory, and executive function in the UT group, and 9–21% of the variance in general cognitive function and verbal learning in the HA group (i.e., medium effect sizes). Audiometric thresholds did not explain any proportion of the variance in cognitive functioning in the HA or UT group. Thus, speech perception in noise accounts for more variance in cognitive performance than audiometric thresholds, and is significantly associated with different cognitive functions in older Chinese adults with HAs and with untreated HL.

Transcranial magnetic stimulation (TMS) safety: a practical guide for psychiatrists

2018 ◽  
Vol 26 (2) ◽  
pp. 189-192 ◽  
Author(s):  
Rohan Taylor ◽  
Veronica Galvez ◽  
Colleen Loo
Keyword(s):  
Older Adults ◽  
Clinical Practice ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Local Pain ◽  
Safety Issues ◽  
Assessment And Monitoring ◽  
Monitoring Treatment ◽  
Site Of Stimulation

Objectives: Repetitive transcranial magnetic stimulation (rTMS) is increasingly being utilised as a treatment option for depression, and with this comes a need for a practical review of safety issues intended for clinicians. This article provides an overview of the current literature regarding safety issues with rTMS for depression, and provides recommendations for clinical practice. Conclusions: Overall, rTMS is a well-tolerated treatment with common side effects (such as headache or local pain at the site of stimulation) being mild. Severe adverse effects, such as seizures, hearing impairment or mania, are uncommon. Certain populations, including adolescents, pregnant women, older adults and those with metal/electronic implants, require special consideration when prescribing and monitoring treatment courses. With adequate assessment and monitoring processes, rTMS can be administered safely in a large proportion of depressed patients.

scholarly journals Transcranial magnetic stimulation reveals diminished homoeostatic metaplasticity in cognitively impaired adults

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Mark H Sundman ◽  
Koeun Lim ◽  
Viet Ton That ◽  
Jack-Morgan Mizell ◽  
Chidi Ugonna ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Transcranial Magnetic Stimulation ◽  
Brain Stimulation ◽  
Magnetic Stimulation ◽  
Cognitive Status ◽  
Synaptic Activity ◽  
Cognitively Impaired ◽  
Non Invasive ◽  
Potential Value

Abstract Homoeostatic metaplasticity is a neuroprotective physiological feature that counterbalances Hebbian forms of plasticity to prevent network destabilization and hyperexcitability. Recent animal models highlight dysfunctional homoeostatic metaplasticity in the pathogenesis of Alzheimer’s disease. However, the association between homoeostatic metaplasticity and cognitive status has not been systematically characterized in either demented or non-demented human populations, and the potential value of homoeostatic metaplasticity as an early biomarker of cognitive impairment has not been explored in humans. Here, we report that, through pre-conditioning the synaptic activity prior to non-invasive brain stimulation, the association between homoeostatic metaplasticity and cognitive status could be established in a population of non-demented human subjects (older adults across cognitive spectrums; all within the non-demented range). All participants (n = 40; age range, 65–74, 47.5% female) underwent a standardized neuropsychological battery, magnetic resonance imaging and a transcranial magnetic stimulation protocol. Specifically, we sampled motor-evoked potentials with an input/output curve immediately before and after repetitive transcranial magnetic stimulation to assess neural plasticity with two experimental paradigms: one with voluntary muscle contraction (i.e. modulated synaptic activity history) to deliberately introduce homoeostatic interference, and one without to serve as a control condition. From comparing neuroplastic responses across these experimental paradigms and across cohorts grouped by cognitive status, we found that (i) homoeostatic metaplasticity is diminished in our cohort of cognitively impaired older adults and (ii) this neuroprotective feature remains intact in cognitively normal participants. This novel finding suggests that (i) future studies should expand their scope beyond just Hebbian forms of plasticity that are traditionally assessed when using non-invasive brain stimulation to investigate cognitive ageing and (ii) the potential value of homoeostatic metaplasticity in serving as a biomarker for cognitive impairment should be further explored.

scholarly journals Auditory Training Using Remembering the Order of Sentences for the Elderly Who Wear Hearing Aids: Is it Effective for Speech Perception in Noise, Working Memory and Reasoning Ability?

2020 ◽  
Vol 16 (2) ◽  
pp. 124-132
Author(s):  
Donghoon Kang ◽  
So Hyun Kim ◽  
Dajung Yun ◽  
Junghwa Bahng
Keyword(s):  
Older Adults ◽  
Working Memory ◽  
Speech Perception ◽  
Hearing Aids ◽  
Hearing Aid ◽  
Self Report ◽  
Auditory Training ◽  
Reasoning Ability ◽  
Speech Perception In Noise ◽  
Reasoning Test

Purpose: The present study examines auditory training outcomes in terms of speech perception in noise, working memory, reasoning ability, and subjective hearing aid satisfaction. Methods: Ten older adults who wear hearing aids (mean age: 71.6) voluntarily participated in the study. For the training material, 78 sentence sets composed of 3 to 5 sentences were used. During the auditory training, participants tried to remember the order of sentences. Among the 78 sentence sets, 45 contained clues and the rest did not. Each participant underwent assessments including speech perception in noise and digit spans and reasoning test and completed a self-report hearing aid satisfaction questionnaire both pre- and post-auditory training. The participants completed eight sessions of the auditory training. Results: The results showed a statistically significant increase in speech recognition ability in noise, short-term memory, and working memory, as well as satisfaction with hearing aid use. Despite a slight increase on the reasoning test, there was no statistically significant improvement.Conclusion: The results of this study suggested that the auditory training in remembering the order of sentences improved speech perception in noise, sensory and working memory, and subjective satisfaction with hearing aids. Future research can investigate more effective auditory training tools to improve the various cognitive skills and communication ability of older adults who wear hearing aids.

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