Plasma from obese children increases monocyte-endothelial adhesion and affects intracellular insulin signaling in cultured endothelial cells: potential role of mTORC1-S6K1

2021 ◽  
pp. 166076
Author(s):  
Nadia Di Pietrantonio ◽  
Carola Palmerini ◽  
Caterina Pipino ◽  
Maria Pompea Antonia Baldassarre ◽  
Giuseppina Bologna ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Insulin Signaling ◽  
Potential Role ◽  
Obese Children ◽  
Cultured Endothelial Cells

Steroid hormones and the stroma-vascular cells of the adipose tissue

2013 ◽  
Vol 15 (1) ◽  
Author(s):  
Fanny Volat ◽  
Anne Bouloumié
Keyword(s):  
Endothelial Cells ◽  
Adipose Tissue ◽  
Progenitor Cells ◽  
Steroid Hormones ◽  
Immune Cells ◽  
Potential Role ◽  
Vascular Cells ◽  
Stroma Vascular Fraction ◽  
Corticosteroid Hormones

AbstractThe stroma-vascular fraction (SVF) of adipose tissue (AT) is a heterogeneous cell fraction composed of progenitor cells, endothelial cells, and immune cells. SVF plays a key role in AT homeostasis and growth as well as in obesity-associated pathologies. The SVF cell composition and phenotype are distinct according to AT location and adiposity. Such discrepancies influence AT function and are involved in obesity-associated disorders such as chronic inflammation. Investigations performed in recent years in rodents and humans provided evidence that the stroma-vascular cells contribute to the conversion of steroid hormones in AT and are also steroid targets. This review describes the link between steroids and SVF depending on gender, adiposity, and AT location and highlights the potential role of sex and corticosteroid hormones in adipogenesis, angiogenesis, and their contributions in AT inflammation.

scholarly journals Angiopoietin-1 inhibits toll-like receptor 4 signalling in cultured endothelial cells: role of miR-146b-5p

2015 ◽  
Vol 106 (3) ◽  
pp. 465-477 ◽  
Author(s):  
Raquel Echavarria ◽  
Dominique Mayaki ◽  
Jean-Charles Neel ◽  
Sharon Harel ◽  
Veronica Sanchez ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Cultured Endothelial Cells ◽  
Angiopoietin 1
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