Down-regulation of GnT-V enhances nasopharyngeal carcinoma cell CNE-2 radiosensitivity in vitro and in vivo

2012 ◽  
Vol 424 (3) ◽  
pp. 554-562 ◽  
Author(s):  
Enqing Zhuo ◽  
Jiao He ◽  
Ting Wei ◽  
Weiliang Zhu ◽  
Hui Meng ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Carcinoma Cell ◽  
Down Regulation ◽  
Nasopharyngeal Carcinoma Cell

Down-regulation of GnT-V inhibits nasopharyngeal carcinoma cell CNE-2 malignancy in vitro and in vivo

2011 ◽  
Vol 309 (2) ◽  
pp. 151-161 ◽  
Author(s):  
Ting Wei ◽  
Yahui Li ◽  
Enqing Zhuo ◽  
Weiliang Zhu ◽  
Hui Meng ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Carcinoma Cell ◽  
Down Regulation ◽  
Nasopharyngeal Carcinoma Cell

Knockdown of annexin VII enhances nasopharyngeal carcinoma cell radiosensitivity in vivo and in vitro

2020 ◽  
Vol 28 (2) ◽  
pp. 129-139
Author(s):  
Si-Jie Gui ◽  
Ru-Lei Ding ◽  
Yan-Ping Wan ◽  
Li Zhou ◽  
Xu-Jun Chen ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Carcinoma Cell ◽  
Nasopharyngeal Carcinoma Cell

Adenovirus-mediated transfer of tris-shRNAs induced apoptosis of nasopharyngeal carcinoma cell in vitro and in vivo

2011 ◽  
Vol 309 (2) ◽  
pp. 162-169 ◽  
Author(s):  
Ji-Bo Han ◽  
Ze-Zhang Tao ◽  
Shi-Ming Chen ◽  
Yong-Gang Kong ◽  
Bo-Kui Xiao
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Carcinoma Cell ◽  
Nasopharyngeal Carcinoma Cell ◽  
Induced Apoptosis

scholarly journals Combination of apoptin with photodynamic therapy induces nasopharyngeal carcinoma cell death in vitro and in vivo

2012 ◽  
Vol 28 (6) ◽  
pp. 2077-2082 ◽  
Author(s):  
XIAOYONG FANG ◽  
PING WU ◽  
JINYUN LI ◽  
LIN QI ◽  
YAOYUN TANG ◽  
...  
Keyword(s):  
Cell Death ◽  
Photodynamic Therapy ◽  
Nasopharyngeal Carcinoma ◽  
Carcinoma Cell ◽  
Nasopharyngeal Carcinoma Cell

scholarly journals Indole-3-carbinol inhibits nasopharyngeal carcinoma cell growth in vivo and in vitro through inhibition of the PI3K/Akt pathway

2014 ◽  
Vol 8 (1) ◽  
pp. 207-212 ◽  
Author(s):  
CHENG-GANG MAO ◽  
ZE-ZHANG TAO ◽  
ZHE CHEN ◽  
CHEN CHEN ◽  
SHI-MING CHEN ◽  
...  
Keyword(s):  
Cell Growth ◽  
Nasopharyngeal Carcinoma ◽  
Carcinoma Cell ◽  
Akt Pathway ◽  
Nasopharyngeal Carcinoma Cell

scholarly journals MiR-130a-3p inhibits the viability, proliferation, invasion, and cell cycle, and promotes apoptosis of nasopharyngeal carcinoma cells by suppressing BACH2 expression

2017 ◽  
Vol 37 (3) ◽  
Author(s):  
Xin Chen ◽  
Bo Yue ◽  
Changming Zhang ◽  
Meihao Qi ◽  
Jianhua Qiu ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Cell Lines ◽  
Cell Apoptosis ◽  
Epithelial Mesenchymal Transition ◽  
Migration And Invasion ◽  
Down Regulation ◽  
Tissue Samples ◽  
Mesenchymal Transition

The aim of the present study was to explore the mechanism through which miR-130a-3p affects the viability, proliferation, migration, and invasion of nasopharyngeal carcinoma (NPC). Tissue samples were collected from the hospital department. NPC cell lines were purchased to conduct the in vitro and in vivo assays. A series of biological assays including MTT, Transwell, and wound healing assays were conducted to investigate the effects of miR-130a-3p and BACH2 on NPC cells. MiR-130a-3p was down-regulated in both NPC tissues and cell lines, whereas BACH2 was up-regulated in both tissues and cell lines. MiR-130a-3p overexpression inhibited NPC cell viability, proliferation, migration, and invasion but promoted cell apoptosis. The converse was true of BACH2, the down-regulation of which could inhibit the corresponding cell abilities and promote apoptosis of NPC cells. The target relationship between miR-130a-3p and BACH2 was confirmed. The epithelial–mesenchymal transition (EMT) pathway was also influenced by miR-130a-3p down-regulation. In conclusion, miR-130a-3p could bind to BACH2, inhibit NPC cell abilities, and promote cell apoptosis.

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