Specific-oxygen-supply functionalized core-shell nanoparticles for smart mutual-promotion between photodynamic therapy and gambogic acid-induced chemotherapy

Biomaterials ◽  
2020 ◽  
Vol 257 ◽  
pp. 120228 ◽  
Author(s):  
Lingfei Han ◽  
Yingming Wang ◽  
Xiaoxian Huang ◽  
Fulei Liu ◽  
Congyu Ma ◽  
...  
Nano Today ◽  
2021 ◽  
Vol 41 ◽  
pp. 101288
Author(s):  
Dengshuai Wei ◽  
Youbai Chen ◽  
Yun Huang ◽  
Peng Li ◽  
Yao Zhao ◽  
...  

2018 ◽  
Vol 54 (68) ◽  
pp. 9525-9528 ◽  
Author(s):  
Feiya Xu ◽  
Yiming Zhao ◽  
Min Hu ◽  
Pu Zhang ◽  
Ning Kong ◽  
...  

We report a novel lanthanide-doped core–shell nanostructure NaYF4:Yb,Er@NaGdF4:Nd@SiO2-RB with a unique design feature that integrates luminescence imaging in biological window II, magnetic resonance imaging, and NIR-excited photodynamic antimicrobial chemotherapy, in a single nanoscale entity.


2010 ◽  
Vol 1257 ◽  
Author(s):  
Juan C. Beltran Huarac ◽  
Surinder P. Singh ◽  
Maharaj S. Tomar ◽  
Sandra Peňa ◽  
Luis Rivera ◽  
...  

AbstractThe use of nanoparticles as carriers of photosensitizer (PS) molecules for photodynamic therapy (PDT) has attracted much interest on core-shell nanosize structures. Herein, we used a simple aqueous solution method to synthesize Fe3O4/ZnO core-shell nanoparticles. X-ray diffraction (XRD) analyses showed the presence of well defined peaks corresponding to Fe3O4 and ZnO in as-synthesized nanocrystals. Vibrating sample magnetometer (VSM) measurements showed that these nanoparticles exhibited superparamagnetic behavior of the core with no coercivity nor remanence. X-ray photoelectron spectroscopy (XPS) analyses revealed the presence of Zn1/2 and Zn3/2 species on the surface of nanocrystals. Photoluminescence measurements showed excitonic emission of ZnO co-existing with a weak and broad defect- related green emission at room temperature. The generation of singlet oxygen was monitored via the photooxidation of diphenyl-1,3-isobenzofuran (DPBF) with different light sources, followed by absorption spectroscopy at 409 nm. The capability of synthesized nanoparticles to generate singlet oxygen has also been verified.


2019 ◽  
Vol 7 (3) ◽  
pp. 1028-1042 ◽  
Author(s):  
Fulei Liu ◽  
Xiaoxian Huang ◽  
Lingfei Han ◽  
Mangmang Sang ◽  
Lejian Hu ◽  
...  

A core-shell hybrid nanoparticle has been developed to improve the druggability of Gambogic acid (GA), a natural antitumor drug candidate.


Author(s):  
Ivana Miletto ◽  
Chiara Gionco ◽  
Maria Cristina Paganini ◽  
Simona Martinotti ◽  
Elia Ranzato ◽  
...  

Small ◽  
2015 ◽  
Vol 11 (21) ◽  
pp. 2527-2535 ◽  
Author(s):  
Young-Kwan Kim ◽  
Hee-Kyung Na ◽  
Seongchan Kim ◽  
Hongje Jang ◽  
Sung-Jin Chang ◽  
...  

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