Physico-chemical characterization and antibacterial activity of inclusion complexes of Hyptis martiusii Benth essential oil in β-cyclodextrin

Background: Fruit peels are considered as waste and contribute towards a major proportion of biomass. They might be a good source of various therapeutic benefits. Peels biomass of citrus fruits are usually considered as garbage. Such peels may have many important and valuable medicinal components with pharmacological activities. Citrus reticulata, (of family Rutaceae, local name tangerine) is a local seasonal fruit in Pakistan which is a very good example regarding wastage of its peels. Objective: The study is based on exploration of a citrus fruit peel derived essential oil, its chemical characterization, identification of various bioactive components and the exploration of pharmacological potentials (antibacterial and wound healing activity). Method: Essential oil was recovered by hydro-distillation of freshly collected peels. Chemical constituents of oil were determined by gas chromatography-mass spectroscopy (GC-MS) analysis. Antioxidant activities were evaluated by total phenolic contents, total flavonoid content, DPPH scavenging activity and reducing power assay. Antibacterial activity was determined using disc diffusion assay. In vivo wound healing potential was determined in rabbits after topical administration of oil. Wound scoring was calculated followed by histological study. Results: GC-MS analysis showed presence of various components with greatest proportion of D-Limonene (89.31%). Total flavonoid and phenolic contents were found to be 14.63 ± 0.95 mg CE/g and 17.03 ± 3.24 mg GAE/g respectively while DPPH activity was found to be 73.32%. Better antibacterial activity was shown against E. coli. In vivo studies showed significant reduction in wound diameter in essential oil treatment groups. Further the essential oil was found non-irritant in draize scoring. Conclusion: The study concluded that essential oil of this fruit peel might be used for antibacterial and wound healing purposes.

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Gefitinib–cyclodextrin inclusion complexes: physico-chemical characterization and dissolution studies

Drug Development and Industrial Pharmacy ◽

10.1080/03639040902783074 ◽

2009 ◽

Vol 35 (9) ◽

pp. 1113-1120 ◽

Cited By ~ 24

Author(s):

Y.-H. Phillip Lee ◽

Sateesh Sathigari ◽

Y.-J. Jean Lin ◽

William R. Ravis ◽

Gurkishan Chadha ◽

...

Keyword(s):

Inclusion Complexes ◽

Chemical Characterization ◽

Dissolution Studies ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion ◽

Physico Chemical

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Production and physico-chemical characterization of nanocapsules of the essential oil from Lippia sidoides Cham.

Industrial Crops and Products ◽

10.1016/j.indcrop.2016.04.013 ◽

2016 ◽

Vol 86 ◽

pp. 279-288 ◽

Cited By ~ 18

Author(s):

Náyra de Oliveira Frederico Pinto ◽

Tigressa Helena Soares Rodrigues ◽

Rita de Cássia Alves Pereira ◽

Lorena Mara Alexandre e Silva ◽

Carlos Alberto Cáceres ◽

...

Keyword(s):

Essential Oil ◽

Chemical Characterization ◽

Lippia Sidoides ◽

Physico Chemical

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Brocchia cinerea essential oil from Brezina (Algerian Sahara): Chemical characterization and antibacterial activity

10.47890/jcsce/2020/acheriti/10082113 ◽

2020 ◽

Vol 1 (1) ◽

Author(s):

Cheriti A ◽

Boukhobza Z ◽

Boulenouar N ◽

Djeradi H ◽

M Kacimi El Hassani ◽

...

Keyword(s):

Antibacterial Activity ◽

Essential Oil ◽

Chemical Characterization ◽

Klebsiella Pneumonia ◽

Gram Positive Bacteria ◽

Oxygenated Monoterpenes ◽

Algerian Sahara ◽

Total Oil ◽

Diffusion Assay ◽

And Staphylococcus Aureus

The essential oil of wild-growing medicinal specie Brocchia cinerea (Asteraceae) from Brezina (Algerian Sahara) was studied for chemical composition by GC/MS analysis and antibacterial activity. Twenty-nine identified components constituted 94.07% of the oil. The most important major components in the oil were trans-Thujone (36.11 %), Camphor (12.08 %), Santolina triene (11.25 %), 1,8-Cineol (6.98 %) and Cis-Verbenyl acetate (6.33 %), together reaching 72.75% of the total oil which is characterized by the presence of high content of oxygenated monoterpenes. The antibacterial activity of the essential oil was tested using the disc diffusion assay. The results showed that the essential oil of Brocchia cinerea had antibacterial activity against all tested Gram-positive bacteria (Enterococcus faecalis and Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli, Klebsiella pneumonia, and Pseudomonas aereginosa). Keywords: Essential Oil; Brocchia Cinerea; GC/MS; Oxygenated Monoterpenes; Antibacterial activity; Sahara;

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