A paper disk equipped with graphene/polyaniline/Au nanoparticles/glucose oxidase biocomposite modified screen-printed electrode: Toward whole blood glucose determination

Abstract A glucose oxidase-peroxidase method for continuous automated monitoring of blood glucose has been developed. The response is linear over the range 0-800 mg/100 ml. Sensitivity can be maintained for 24 hr or longer and can be restored by rinsing the analytic system with sulfuric acid to permit studies of longer than 48 hr in duration. A precision of ± 1% can be maintained between rinses for samples containing 100-600 mg of glucose per 100 ml. This method is satisfactorily specific for glucose: The response with other sugars is less than 1% of the response obtained with the same concentration of glucose. Ascorbic acid causes no significant inhibition of the response to glucose. The inhibition by uric acid has been reduced fifty-fold compared to that in other methods. Transit through the sampling catheter and analytic system requires 15 min. Timed from the first detectable response to a change in concentration, 25% of total response is achieved in 30 sec and 90% in 80 sec. Fifty percent of an oscillation with a half-period of 45 sec can be detected; no oscillations this short were observed in records of human blood glucose. Applicability and feasibility of this method have been demonstrated in over 2000 hr of repeated blood glucose recordings in 12 diabetic and 6 normal subjects.

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Enzymatic Blood Glucose Determination by Colorimetry of N,N-Diethylaniline-4-Aminoantipyrine

Clinical Chemistry ◽

10.1093/clinchem/20.5.606 ◽

1974 ◽

Vol 20 (5) ◽

pp. 606-607 ◽

Cited By ~ 31

Author(s):

Peter Kabasakalian ◽

Sami Kalliney ◽

Anita Westcott

Keyword(s):

Hydrogen Peroxide ◽

Blood Glucose ◽

Glucose Oxidase ◽

Oxidative Coupling ◽

Room Temperature ◽

Glucose Determination ◽

Final Volume ◽

Blood Glucose Determination

Abstract The hydrogen peroxide produced from glucose by glucose oxidase action at pH 7 is determined by the peroxidase oxidative coupling of N,N-diethylaniline with 4-amino-antipyrine. A 20-µl sample of plasma or serum is reacted at room temperature for 10 min. The sensitivity of the method is such that 60 µg of glucose (300 mg/dl) in a final volume of 5 ml gives an absorbance of 0.8 at 553 nm with a 1-cm cell. Absorbances are linearly related to glucose concentrations as high as 10.00 g/liter.

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Interference by acetaminophen in the glucose oxidase-peroxidase method for blood glucose determination.

Clinical Chemistry ◽

10.1093/clinchem/22.10.1729 ◽

1976 ◽

Vol 22 (10) ◽

pp. 1729-1731 ◽

Cited By ~ 16

Author(s):

I Kaufmann-Raab ◽

H G Jonen ◽

E Jähnchen ◽

G F Kahl ◽

U Groth

Keyword(s):

Blood Glucose ◽

Glucose Oxidase ◽

Analytical Procedure ◽

Phenolic Hydroxyl ◽

Hydroxyl Group ◽

Glucose Determination ◽

Apparent Loss ◽

Blood Glucose Determination ◽

Glucose 6 Phosphate Dehydrogenase ◽

Related Compounds

Abstract Acetaminophen, p-aminophenol, and oxyphenbutazone interfere with the glucose oxidase/peroxidase method for glucose. Structurally related compounds that lack a free phenolic hydroxyl group (acetanilide, aniline, and phenylbutazone) do not interfere. During the analytical procedure acetaminophen is consumed. One mole of acetaminophen leads to an apparent loss of four moles of glucose. The hexokinase/glucose-6-phosphate dehydrogenase method (Boehringer Hexokinase method) is not affected by these substances.

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Whole Blood Glucose Determination in Newborn Infants, Comparison and Evaluation of Five Different Methods

Acta Paediatrica ◽

10.1111/j.1651-2227.1967.tb15409.x ◽

1967 ◽

Vol 56 (5) ◽

pp. 461-466 ◽

Cited By ~ 3

Author(s):

JOHAN EK ◽

LUDVIG N. W. DAAE

Keyword(s):

Blood Glucose ◽

Whole Blood ◽

Newborn Infants ◽

Glucose Determination ◽

Blood Glucose Determination

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Errata

Clinical Chemistry ◽

10.1093/clinchem/15.12.1248 ◽

1969 ◽

Vol 15 (12) ◽

pp. 1248-1248

Keyword(s):

Blood Glucose ◽

Glucose Oxidase ◽

Glucose Determination ◽

True Value ◽

Blood Glucose Determination

Abstract In Rosevear, J. W. et al: "Glucose Oxidase Method for Continuous Automated Blood Glucose Determination, 15:680, 1969 in the Journal, the bottom of the whole paragraph on page 681 should have read: For a range of 0-500 mg/100 ml, the error equivalent to ±0.2% transmittance would be ±5% of the true value at 50 mg/100 ml, ±2% at 100, ±1% at 200, and ±3% at 500 mg/100 ml. For a range of 0-250 mg/100 ml (30-100% transmittance), the error equivalent to ±0.2% transmittance would be at least ±2% at 50 mg/100 ml and ±1% at 100 mg/100 ml.

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