Highly sensitive detection of cysteine over glutathione and homo-cysteine: New insight into the Michael addition of mercapto group to maleimide

2017 ◽  
Vol 91 ◽  
pp. 553-559 ◽  
Author(s):  
Zhaoyang Chen ◽  
Qian Sun ◽  
Yuhua Yao ◽  
Xiaoxiang Fan ◽  
Weibing Zhang ◽  
...  
Sensors ◽  
2018 ◽  
Vol 18 (12) ◽  
pp. 4304 ◽  
Author(s):  
Hee Shin ◽  
Hae Jang ◽  
Gyeongsik Ok

In this study, we demonstrated a highly sensitive detection method of 4-methylimidazole (4-MeI), a carcinogenic material, by using a terahertz (THz) metamaterial at a THz region. The THz metamaterials were fabricated with a metal array, using an electric-field-coupled inductor-capacitor (ELC) resonator structure, and a finite-difference time-domain (FDTD) simulation showed good agreement with the experimental results. We measured the THz spectra of the metamaterials to detect the 4-MeI concentrations of 0, 1, 2, 5, 10, 15, and 20 mg/L. The resonance frequency of the metamaterial was shifted by, approximately, 8 GHz and transmittance at the resonance frequency increased to 2 × 10−3, as the concentration was increased, up to 20 mg/L. Our study provides new insight into the application of metamaterials in detecting carcinogens, using a THz technique.


RSC Advances ◽  
2015 ◽  
Vol 5 (23) ◽  
pp. 17797-17801 ◽  
Author(s):  
Kunzhu Huang ◽  
Lun Yu ◽  
Pengfei Xu ◽  
Xintong Zhang ◽  
Wenbin Zeng

A novel ratiometric and colorimetric probeH2S-CRfor the quantitative detection of H2S was designed and synthesized based on a H2S induced Michael addition–cyclization cascade reaction and the FRET modulated fluorescence off-on response.


Author(s):  
Xiaojia Jiang ◽  
Mingsong Zang ◽  
Fei Li ◽  
Chunxi Hou ◽  
Quan Luo ◽  
...  

Biological nanopore-based techniques have attracted more and more attention recently in the field of single-molecule detection, because they allow the real-time, sensitive, high-throughput analysis. Herein, we report an engineered biological...


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