“Management of sagittal craniosynostosis: morphological comparison of 8 surgical techniques”

2021 ◽  
Author(s):  
Leila Galiay ◽  
Quentin Hennocq ◽  
Connor Cross ◽  
Eric Arnaud ◽  
Dawid Larysz ◽  
...  
Keyword(s):  
Surgical Techniques ◽  
Morphological Comparison ◽  
Sagittal Craniosynostosis

scholarly journals Predicting calvarial morphology in sagittal craniosynostosis

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Oyvind Malde ◽  
Connor Cross ◽  
Chien L. Lim ◽  
Arsalan Marghoub ◽  
Michael L. Cunningham ◽  
...  
Keyword(s):  
Finite Element ◽  
Input Parameter ◽  
Surgical Techniques ◽  
Element Model ◽  
Specific Model ◽  
Patient Specific ◽  
Sagittal Craniosynostosis ◽  
Sensitivity Tests ◽  
Ct Data

AbstractEarly fusion of the sagittal suture is a clinical condition called, sagittal craniosynostosis. Calvarial reconstruction is the most common treatment option for this condition with a range of techniques being developed by different groups. Computer simulations have a huge potential to predict the calvarial growth and optimise the management of this condition. However, these models need to be validated. The aim of this study was to develop a validated patient-specific finite element model of a sagittal craniosynostosis. Here, the finite element method was used to predict the calvarial morphology of a patient based on its preoperative morphology and the planned surgical techniques. A series of sensitivity tests and hypothetical models were carried out and developed to understand the effect of various input parameters on the result. Sensitivity tests highlighted that the models are sensitive to the choice of input parameter. The hypothetical models highlighted the potential of the approach in testing different reconstruction techniques. The patient-specific model highlighted that a comparable pattern of calvarial morphology to the follow up CT data could be obtained. This study forms the foundation for further studies to use the approach described here to optimise the management of sagittal craniosynostosis.

Surgical Advancement Influences Perioperative Care: A Comparison of Two Surgical Techniques for Sagittal Craniosynostosis Repair

2003 ◽  
pp. 699-703 ◽  
Author(s):  
Douglas G. Ririe ◽  
Lisa R. David ◽  
Steven S. Glazier ◽  
Timothy E. Smith ◽  
Louis C. Argenta
Keyword(s):  
Perioperative Care ◽  
Surgical Techniques ◽  
Sagittal Craniosynostosis

scholarly journals Predicting and comparing three corrective techniques for sagittal craniosynostosis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Connor Cross ◽  
Roman H. Khonsari ◽  
Dawid Larysz ◽  
David Johnson ◽  
Lars Kölby ◽  
...  
Keyword(s):  
Finite Element ◽  
Surgical Techniques ◽  
Morphological Characteristics ◽  
Neurocognitive Deficits ◽  
Sagittal Synostosis ◽  
Sagittal Craniosynostosis ◽  
Reconstruction Methods ◽  
The Impact ◽  
The Brain

AbstractSagittal synostosis is the most occurring form of craniosynostosis, resulting in calvarial deformation and possible long-term neurocognitive deficits. Several surgical techniques have been developed to correct these issues. Debates as to the most optimal approach are still ongoing. Finite element method is a computational tool that’s shown to assist with the management of craniosynostosis. The aim of this study was to compare and predict the outcomes of three reconstruction methods for sagittal craniosynostosis. Here, a generic finite element model was developed based on a patient at 4 months of age and was virtually reconstructed under all three different techniques. Calvarial growth was simulated to predict the skull morphology and the impact of different reconstruction techniques on the brain growth up to 60 months of age. Predicted morphology was then compared with in vivo and literature data. Our results show a promising resemblance to morphological outcomes at follow up. Morphological characteristics between considered techniques were also captured in our predictions. Pressure outcomes across the brain highlight the potential impact that different techniques have on growth. This study lays the foundation for further investigation into additional reconstructive techniques for sagittal synostosis with the long-term vision of optimizing the management of craniosynostosis.

scholarly journals Spring-assisted minimally invasive repair of sagittal craniosynostosis

2021 ◽  
Vol 4 (2) ◽  
pp. V8
Author(s):  
Lance S. Governale ◽  
Jessica A. Ching
Keyword(s):  
Intracranial Pressure ◽  
Minimally Invasive ◽  
Recovery Time ◽  
Developmental Delays ◽  
Surgical Techniques ◽  
Increased Intracranial Pressure ◽  
Link Type ◽  
Sagittal Craniosynostosis ◽  
Minimally Invasive Surgical ◽  
Cranial Deformity

Craniosynostosis surgery is intended to repair cranial deformity, reduce the risk of increased intracranial pressure from cephalocranial disproportion, and reduce the risk of developmental delays. In recent years, minimally invasive surgical techniques have been developed to achieve these goals with less tissue disruption, lower rates of transfusion, and shorter recovery time. The operation focuses on unlocking the fused bones, while reshaping relies on an adjunct, most commonly a postoperative cranial molding helmet. As an alternative to the care-intensive helmeting process, reshaping with implanted cranial expander springs has emerged. In this video, the authors demonstrate their technique for spring-assisted minimally invasive repair of sagittal craniosynostosis. The video can be found here: https://vimeo.com/513923721

Ultrastructure and Morphology of the Neurospora Crassa Cell Wall Mutants, Slime And Slime X, Using Tem and Sem

1976 ◽  
Vol 34 ◽  
pp. 54-55
Author(s):  
Karen S. Howard ◽  
H. D. Braymer ◽  
M. D. Socolofsky ◽  
S. A. Milligan
Keyword(s):  
Cell Wall ◽  
Neurospora Crassa ◽  
Wild Type ◽  
Morphological Comparison ◽  
Small Areas ◽  
Solid Media ◽  
Thin Sectioning ◽  
X Cells ◽  
Mutant Cells ◽  
Isolated Cell

The recently isolated cell wall mutant slime X of Neurospora crassa was prepared for ultrastructural and morphological comparison with the cell wall mutant slime. The purpose of this article is to discuss the methods of preparation for TEM and SEM observations, as well as to make a preliminary comparison of the two mutants.TEM: Cells of the slime mutant were prepared for thin sectioning by the method of Bigger, et al. Slime X cells were prepared in the same manner with the following two exceptions: the cells were embedded in 3% agar prior to fixation and the buffered solutions contained 5% sucrose throughout the procedure.SEM: Two methods were used to prepare mutant and wild type Neurospora for the SEM. First, single colonies of mutant cells and small areas of wild type hyphae were cut from solid media and fixed with OSO4 vapors similar to the procedure used by Harris, et al. with one alteration. The cell-containing agar blocks were dehydrated by immersion in 2,2-dimethoxypropane (DMP).

Surgical Techniques in the Treatment of Pancreatic Pseudocysts

Swiss Surgery ◽  
2003 ◽  
Vol 9 (3) ◽  
pp. 131-134
Author(s):  
Röthlin
Keyword(s):  
Surgical Techniques ◽  
Pancreatic Pseudocysts

Anhand der Pseudozysteneinteilung nach D'Egidio und Schein werden die verschiedenen chirurgischen Techniken der Pseudozystendrainage und -resektion diskutiert. Die Möglichkeiten und Grenzen der laparoskopischen Technik werden dargestellt. Auf die "Konkurrenz" der endoskopischen und interventionellen Therapien wird lediglich am Rand verwiesen. Prognostisch hängt der weitere Verlauf nach Pseudozystenoperation weniger von der Operationstechnik, als vom natürlichen Verlauf der Erkrankung (chron. Pankreatitis) und vom Sistieren, bzw. Weiterbestehen der zugrundeliegenden Noxe ab.

Current Strategies in the Management of Spinal Metastatic Disease

Swiss Surgery ◽  
2003 ◽  
Vol 9 (2) ◽  
pp. 55-62 ◽  
Author(s):  
Bartanusz ◽  
Porchet
Keyword(s):  
Spinal Cord ◽  
Surgical Techniques ◽  
Cord Compression ◽  
Treatment Modalities ◽  
Surgical Approaches ◽  
Spinal Stabilization ◽  
Management Algorithm ◽  
Specific Manner ◽  
Extensive Surgery ◽  
Selection Of

The treatment of metastatic spinal cord compression is complex. The three treatment modalities that are currently applied (in a histologically non-specific manner) are surgery, radiotherapy and the administration of steroids. The development of new spinal instrumentations and surgical approaches considerably changed the extent of therapeutic options in this field. These new surgical techniques have made it possible to resect these tumours totally, with subsequent vertebral reconstruction and spinal stabilization. In this respect, it is important to clearly identify those patients who can benefit from such an extensive surgery. We present our management algorithm to help select patients for surgery and at the same time identifying those for whom primary non-surgical therapy would be indicated. The retrospective review of surgically treated patients in our department in the last four years reveals a meagre application of conventional guidelines for the selection of the appropriate operative approach in the surgical management of these patients. The reasons for this discrepancy are discussed.

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