Microwave-assisted synthesis of phenanthroimidazole derivatives as stabilizer of c-myc G-quadruplex DNA

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2014.09.003 ◽

2014 ◽

Vol 22 (22) ◽

pp. 6503-6508 ◽

Author(s):

Siyan Liao ◽

Zhao Zhang ◽

Qiong Wu ◽

Xicheng Wang ◽

Wenjie Mei

Keyword(s):

Microwave Assisted Synthesis ◽

Quadruplex Dna ◽

Microwave Assisted ◽

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Microwave-Assisted Synthesis of Imidazo[4,5-f][1,10]phenanthroline Derivatives as Apoptosis Inducers in Chemotherapy by Stabilizing Bcl-2 G-quadruplex DNA

Molecules ◽

10.3390/molecules22050829 ◽

2017 ◽

Vol 22 (5) ◽

pp. 829

Author(s):

Li Li ◽

Jie-Qiong Cao ◽

Hui-Min Liu ◽

Qiong Wu ◽

Qiu-Hui Pan ◽

...

Keyword(s):

Microwave Assisted Synthesis ◽

Quadruplex Dna ◽

Microwave Assisted ◽

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Microwave-Assisted Synthesis of Arene Ru(II) Complexes Induce Tumor Cell Apoptosis Through Selectively Binding and Stabilizing bcl-2 G-Quadruplex DNA

Materials ◽

10.3390/ma9050386 ◽

2016 ◽

Vol 9 (5) ◽

pp. 386 ◽

Author(s):

Yanhua Chen ◽

Qiong Wu ◽

Xicheng Wang ◽

Qiang Xie ◽

Yunyun Tang ◽

...

Keyword(s):

Cell Apoptosis ◽

Microwave Assisted Synthesis ◽

Tumor Cell Apoptosis ◽

Quadruplex Dna ◽

Microwave Assisted ◽

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Microwave-assisted synthesis of ruthenium(II) complexes with alkynes as potential inhibitor by selectively recognizing c-myc G-quadruplex DNA

Journal of Inorganic Biochemistry ◽

10.1016/j.jinorgbio.2017.08.005 ◽

2017 ◽

Vol 176 ◽

pp. 113-122 ◽

Author(s):

Shuangyan Zhang ◽

Qiong Wu ◽

Hao Zhang ◽

Qi Wang ◽

Xicheng Wang ◽

...

Keyword(s):

Microwave Assisted Synthesis ◽

Quadruplex Dna ◽

Microwave Assisted ◽

Potential Inhibitor ◽

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Cationic Pentaheteroaryls as Selective G-Quadruplex Ligands by Solvent-Free Microwave-Assisted Synthesis

Chemistry - A European Journal ◽

10.1002/chem.201202097 ◽

2012 ◽

Vol 18 (45) ◽

pp. 14487-14496 ◽

Author(s):

Michele Petenzi ◽

Daniela Verga ◽

Eric Largy ◽

Florian Hamon ◽

Filippo Doria ◽

...

Keyword(s):

Solvent Free ◽

Microwave Assisted Synthesis ◽

Microwave Assisted ◽

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Microwave-assisted synthesis of Cd (II) complex of 4-pyridinecarboxaldehyde thiosemicarbazone

10.3390/ecsoc-17-c007 ◽

2013 ◽

Author(s):

Azadeh Tadjarodi ◽

Homayoun Gholipour

Keyword(s):

Microwave Assisted Synthesis ◽

Microwave Assisted

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Conventional and Microwave Assisted Synthesis with Antimicrobial Evaluation of Novel Pyrrolidine Molecule: An Approach to Easy Synthetic Pathway

Journal of Chemistry and Chemical Sciences ◽

10.29055/jccs/585 ◽

2018 ◽

Vol 8 (2) ◽

pp. 298-303

Author(s):

K Sreekanth ◽

Anjali Jha

Keyword(s):

Microwave Assisted Synthesis ◽

Synthetic Pathway ◽

Microwave Assisted ◽

Antimicrobial Evaluation

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Microwave Assisted Synthesis of Cationic Amino Sugar Surfactants

Tenside Surfactants Detergents ◽

10.3139/113.110684 ◽

2020 ◽

Vol 57 (3) ◽

pp. 265-272

Author(s):

Priya S. Singh ◽

Aizaz Shaikh ◽

Aditi Deshmukh ◽

Amit P. Pratap

Keyword(s):

Amino Sugar ◽

Microwave Assisted Synthesis ◽

Microwave Assisted

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MICROWAVE ASSISTED SYNTHESIS, QSAR AND MOLECULAR DOCKING STUDIES OF 2,4- THIAZOLIDINEDIONE DERIVATIVES

RASAYAN Journal of Chemistry ◽

10.31788/rjc.2019.1235165 ◽

2019 ◽

Vol 12 (03) ◽

pp. 1063-1071

Author(s):

B . Geetha ◽

G . Swarnalatha ◽

G.V . Subba Reddy

Keyword(s):

Molecular Docking ◽

Docking Studies ◽

Microwave Assisted Synthesis ◽

Molecular Docking Studies ◽

Microwave Assisted

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Efficient One-pot microwave-assisted Synthesis and Spectroscopic Characterization of Novel Antitumor and Antimicrobial Hydroxypyrrolidin2-ones

Journal of Scientific Research in Science ◽

10.21608/jsrs.2018.15776 ◽

2018 ◽

Vol 35 (part 1) ◽

pp. 1-16

Author(s):

Eman Azmy ◽

Boshra Awad ◽

Halima Hefni ◽

Hanaa Saad ◽

Affaf Eltoukhy ◽

...

Keyword(s):

Spectroscopic Characterization ◽

Microwave Assisted Synthesis ◽

One Pot ◽

Microwave Assisted

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Hybrid Imidazole-Pyridine Derivatives: An Approach to Novel Anticancer DNA Intercalators

Current Medicinal Chemistry ◽

10.2174/0929867326666181220094229 ◽

2020 ◽

Vol 27 (1) ◽

pp. 154-169 ◽

Author(s):

Claudiu N. Lungu ◽

Bogdan Ionel Bratanovici ◽

Maria Mirabela Grigore ◽

Vasilichia Antoci ◽

Ionel I. Mangalagiu

Keyword(s):

Experimental Data ◽

Antimicrobial Properties ◽

Therapeutic Effectiveness ◽

Computational Results ◽

Pyridine Derivatives ◽

Quadruplex Dna ◽

Dna Intercalators ◽

Structure Activity ◽

Lack of specificity and subsequent therapeutic effectiveness of antimicrobial and antitumoral drugs is a common difficulty in therapy. The aim of this study is to investigate, both by experimental and computational methods, the antitumoral and antimicrobial properties of a series of synthesized imidazole-pyridine derivatives. Interaction with three targets was discussed: Dickerson-Drew dodecamer (PDB id 2ADU), G-quadruplex DNA string (PDB id 2F8U) and DNA strain in complex with dioxygenase (PDB id 3S5A). Docking energies were computed and represented graphically. On them, a QSAR model was developed in order to further investigate the structure-activity relationship. Results showed that synthesized compounds have antitumoral and antimicrobial properties. Computational results agreed with the experimental data.

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