scholarly journals Probing Membrane Protein Sequestration and Oligomerization in Polymer-Tethered Phospholipid Bilayers Containing Raft-Mimicking Lipid Mixtures

2015 ◽  
Vol 108 (2) ◽  
pp. 1a-2a
Author(s):  
Christoph Naumann
Keyword(s):  
Membrane Protein ◽  
Phospholipid Bilayers ◽  
Lipid Mixtures ◽  
Protein Sequestration

The thermodynamic properties of mixed phospholipid bilayers: a theoretical analysis

1984 ◽  
Vol 62 (8) ◽  
pp. 796-802 ◽  
Author(s):  
Maryse Mondat ◽  
A. Georgallas ◽  
D. A. Pink ◽  
M. J. Zuckermann
Keyword(s):  
Experimental Data ◽  
Thermodynamic Properties ◽  
Reasonable Agreement ◽  
Phospholipid Bilayers ◽  
Scanning Calorimetry ◽  
Phase Separations ◽  
Lipid Mixtures ◽  
Wide Range ◽  
Acyl Chains ◽  
Gel Phase

A theoretical model is presented with the intention of describing lateral phase separations in binary lipid mixtures in which the acyl chains of the components differ in their length. The model includes explicitly interactions between the acyl chains and between polar heads of the lipid molecules. Phase diagrams and thermodynamic properties of binary lipid mixtures were calculated using a wide range of interaction parameters. It is shown that the occurrence of immiscibility in the gel phase is related to the interactions between the polar heads of the lipid molecules. The calculated results for binary lipid mixtures are compared with the available experimental data. In particular, the calculated specific heat for dilauroyl phosphatidylcholine – distearoyl phosphatidylcholine is in reasonable agreement with experimental results obtained from differential scanning calorimetry measurements.

X-Ray Studies on Phospholipid Bilayers. V. Interactions with DDT

1985 ◽  
Vol 40 (7-8) ◽  
pp. 566-570 ◽  
Author(s):  
M. Suwalsky ◽  
N. Bugueño ◽  
J. Tapia ◽  
F. Neira
Keyword(s):  
Phospholipid Bilayers ◽  
X Ray Diffraction ◽  
X Ray ◽  
Molar Ratios ◽  
Lipid Mixtures ◽  
Oriented Films

Abstract The possible interaction of DDT with the lipids dimyristoyl lecithin (DML), dipalmitoylphos-phatidylethanolamine (DPPE) and tripalmitin (TP) was studied. The work was carried out on oriented films and crystalline powders of DDT-lipid mixtures at different molar ratios by X-ray diffraction techniques. The diagrams showed only the patterns of pure DDT and that of the corresponding lipid. It is concluded that new phases were not formed and, therefore, no interactions occurred.

scholarly journals Bilayer Asymmetry, Cholesterol Content, and Ligand Binding Influence Membrane Protein Sequestering in Raft-Mimicking Lipid Mixtures

2013 ◽  
Vol 104 (2) ◽  
pp. 43a
Author(s):  
Noor F. Hussain ◽  
Yifan Ge ◽  
Amanda P. Siegel ◽  
Rainer Jordan ◽  
Christoph A. Naumann
Keyword(s):  
Membrane Protein ◽  
Ligand Binding ◽  
Cholesterol Content ◽  
Lipid Mixtures

The Effect of Charge on Melittin-Induced Changes in Membrane Structure and Morphology

2020 ◽  
Vol 73 (3) ◽  
pp. 195 ◽  
Author(s):  
Tzong-Hsien Lee ◽  
Kristopher Hall ◽  
Marie-Isabel Aguilar
Keyword(s):  
Structural Changes ◽  
Morphological Changes ◽  
Membrane Surface ◽  
Phospholipid Bilayers ◽  
Membrane Disruption ◽  
Force Microscopy ◽  
Atomic Force ◽  
Lipid Mixtures ◽  
Dual Polarisation Interferometry ◽  
Induced Changes

The binding of melittin to a range of phospholipid bilayers was studied using dual polarisation interferometry and atomic force microscopy. The phospholipid model membranes included zwitterionic dimyristylphosphatidylcholine (DMPC), together with mixtures of DMPC/dimyristylphosphatidylglycerol (DMPG) and DMPC/DMPG/cholesterol. Melittin caused significant disruption on all bilayers, but differences in morphological changes during binding were different on each membrane. Overall, the results demonstrate that the process of membrane disruption follows distinct structural changes for different lipid mixtures irrespective of the strength of binding to the membrane surface.

scholarly journals Membrane Protein Frustration: Protein Incorporation into Hydrophobic Mismatched Binary Lipid Mixtures

2009 ◽  
Vol 96 (4) ◽  
pp. 1408-1414 ◽  
Author(s):  
David Stopar ◽  
Ruud B. Spruijt ◽  
Marcus A. Hemminga
Keyword(s):  
Membrane Protein ◽  
Lipid Mixtures ◽  
Protein Incorporation

A new functional membrane protein microarray based on tethered phospholipid bilayers

The Analyst ◽  
2018 ◽  
Vol 143 (9) ◽  
pp. 2165-2173 ◽  
Author(s):  
Meriem Chadli ◽  
Ofelia Maniti ◽  
Christophe Marquette ◽  
Bruno Tillier ◽  
Sandra Cortès ◽  
...  
Keyword(s):  
Membrane Protein ◽  
Lipid Membranes ◽  
Protein Microarray ◽  
Phospholipid Bilayers ◽  
Bilayer Lipid Membranes ◽  
Bilayer Lipid ◽  
Functional Membrane

A new membrane protein microarray based on peptide-tethered bilayer lipid membranes formed by the fusion of cell-free expressed proteoliposomes inside micropatterned microwells.

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