scholarly journals Effect of the combined use of vagus nerve stimulation and antiepileptic drugs in an experimental model of audiogenic epilepsy, the GASH/Sal

2021 ◽  
Vol 14 (6) ◽  
pp. 1605
Author(s):  
Jaime Gonçalves-Sánchez ◽  
Consuelo Sancho ◽  
Dolores E. López ◽  
Orlando Castellano ◽  
Sergio Márquez-Sánchez ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Antiepileptic Drugs ◽  
Experimental Model ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Audiogenic Epilepsy ◽  
Combined Use

Infantile Spasms and Lennox-Gastaut Syndrome

2002 ◽  
Vol 17 (2_suppl) ◽  
pp. 2S9-2S22 ◽  
Author(s):  
Edwin Trevathan
Keyword(s):  
Vagus Nerve ◽  
Antiepileptic Drugs ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Seizure Control ◽  
Treatment Options ◽  
Clinical Manifestations ◽  
Infantile Spasms ◽  
Corpus Callosotomy ◽  
New Antiepileptic Drugs

Infantile spasms and Lennox-Gastaut syndrome are rare but are important to child neurologists because of the intractable nature of the seizures and the serious neurologic comorbidities. New antiepileptic drugs offer more alternatives for treating both infantile spasms and Lennox-Gastaut syndrome. Selected children with infantile spasms are candidates for epilepsy surgery. Vagus nerve stimulation, corpus callosotomy, and the ketogenic diet are all options for selected children with Lennox-Gastaut syndrome. The epidemiology, clinical manifestations of the seizures, electroencephalographic characteristics, prognosis, and treatment options are reviewed for infantile spasms and Lennox-Gastaut syndrome. Additional therapies are needed for both infantile spasms and Lennox-Gastaut syndrome as many children fail to achieve adequate seizure control in spite of newer treatments. (J Child Neurol 2002;17:2S9—2S22).

scholarly journals Forbedring av rutiner rundt pasienter med vagusnervestimulator

2015 ◽  
Vol 10 (2) ◽  
pp. 151
Author(s):  
Christine Tørris ◽  
Kari Helen Schøyen ◽  
Elin Merete Wiklund
Keyword(s):  
Vagus Nerve ◽  
Antiepileptic Drugs ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Additional Dose ◽  
Nerve Stimulator ◽  
Vagus Nerve Stimulator ◽  
Before And After ◽  
Storage Area ◽  
And Storage

<p>Improving routines for patients with vagus nerve stimulation</p><p>Background: Vagus Nerve Stimulator (VNS) is a form of therapy which may reduce the frequency of seizures in people with epilepsy, who do not achieve remission with antiepileptic drugs. A corresponding magnet providing an additional dose of stimulation may stop or shorten the intensity of the seizure.</p><p>Objective Investigate the practice and procedure regarding use and storage of a VNS Therapy magnet, to see whether introduction of a new routine with a permanent seat for VNS magnet may contribute to increased availability of the magnet.</p><p>Method Registration of the magnets location was performed before, and after the magnetic board intervention. In addition staff answered a questionnaire related to experiences around storage of magnet.</p><p>Results The number of not located magnets dropped from 70% to 25 % after the intervention.</p><p>Conclusion A magnetic board as a storage area for VNS magnet on the patient's room increases the availability of the magnet.</p>

The effectiveness of vagus nerve stimulation after failed surgical treatment of pharmacoresistant epilepsy

2021 ◽  
pp. 19-35
Author(s):  
Igor Trifonov ◽  
Mikhail Sinkin ◽  
Alexandra Nekhoroshikh
Keyword(s):  
Surgical Treatment ◽  
Vagus Nerve ◽  
Antiepileptic Drugs ◽  
Nerve Stimulation ◽  
Alternative Treatment ◽  
Vagus Nerve Stimulation ◽  
Pharmacoresistant Epilepsy ◽  
Wide Range ◽  
The World ◽  
Promising Type

According to the WHO, about 50 million people in the world suffer from epilepsy, while 20–40 % are resistant to antiepileptic drugs and need alternative treatment methods. The arsenal of neurosurgeons includes a wide range of operations that have proven effectiveness in the fight against pharmacoresistant epilepsy. Such a promising type of treatment as vagus nerve stimulation can be used both with contraindicated resection surgery and after it. Currently, the field of VNS therapy continues to be explored, including the efficiency and rationality of its use.

scholarly journals Efficienc y of vag us nerve stim ulation in epilepsy (literat ure review and case report )

2019 ◽  
Vol 14 (2) ◽  
pp. 7-17
Author(s):  
O. A. Pylaeva ◽  
V. A. Chadaev ◽  
M. Yu. Bobylova ◽  
K. Yu. Mukhin
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Vagus Nerve ◽  
Antiepileptic Drugs ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Drug Resistant ◽  
Treatment Resistant ◽  
Drug Resistant Epilepsy ◽  
Patients With Epilepsy

Despite significant advances in epileptology, approximately one-third of patients suffer from drug-resistant epilepsy. Numerous approaches are currently available to treat epilepsy; however, there are still many patients with treatment-resistant epilepsy, in whom antiepileptic drugs are ineffective and surgical treatment is impossible. Thus, searching for new effective antiepileptic drugs and alternative treatments (such as vagus nerve stimulation) for these patients remains highly relevant. This literature review covers the indications for and the efficacy and tolerability of vagus nerve stimulation in patients with epilepsy. We also report a case of successful treatment of a patient with drug-resistant epilepsy using this method.

scholarly journals Epileptologists probe vagus nerve stimulation in children with refractory epilepsy: a promise against sudden unexpected death in epilepsy

2012 ◽  
Vol 70 (12) ◽  
pp. 953-955 ◽  
Author(s):  
Vera C. Terra ◽  
Meire A. Nisyiama ◽  
João Abrão ◽  
Américo C. Sakamoto ◽  
Helio R. Machado ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Children And Adolescents ◽  
Antiepileptic Drugs ◽  
Clinical Efficacy ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Refractory Epilepsy ◽  
Sudden Unexpected Death ◽  
Pharmacological Treatments ◽  
Unexpected Death

It is clear that sudden unexpected death in epilepsy (SUDEP) is mainly a problem for people with refractory epilepsy, but our understanding of the best way to its prevention is still incomplete. Although the pharmacological treatments available for epilepsies have expanded, some antiepileptic drugs are still limited in clinical efficacy. In the present paper, we described an experience with vagus nerve stimulation (VNS) treatment by opening space and providing the opportunity to implement effective preventative maps to reduce the incidence of SUDEP in children and adolescents with refractory epilepsy.

scholarly journals Vagus nerve stimulation in chronic refractory epilepsy: chasing the cardiologist

2021 ◽  
Author(s):  
Ansh Chaudhary ◽  
Bhupendra Chaudhary
Keyword(s):  
Electrical Stimulation ◽  
Vagus Nerve ◽  
Antiepileptic Drugs ◽  
Nerve Stimulation ◽  
Side Effect ◽  
Neurological Disorder ◽  
Vagus Nerve Stimulation ◽  
Refractory Epilepsy ◽  
Stimulation Of

Epilepsy the second most common chronic neurological disorder after stroke affect 0.5-2% population worldwide. Antiepileptic drugs though remain the corner stone in management of epilepsy in majority of patients but still 30% of patients continues to have seizure or experience unacceptable pharmacological side effect. Electrical stimulation of vagus nerve is an effective and promising neurophysiological treatment for patients with refractory epilepsy who are either unsuitable candidate of surgery or falls in category of surgically refractory epilepsy. 

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