Lubricant and razor debridement in partial thickness burn

Burns ◽  
2005 ◽  
Vol 31 (7) ◽  
pp. 915-917 ◽  
Author(s):  
Luca A. Dessy ◽  
M. Dalvi Humzah ◽  
Raul L.M. Ranno ◽  
Carmine Alfano
Keyword(s):  
Partial Thickness ◽  
Partial Thickness Burn

scholarly journals Amnion Membrane Graft Dressing in Superficial Partial Thickness Burn in Pediatric Patients

2015 ◽  
Vol 14 (1) ◽  
pp. 22-25
Author(s):  
Md Saif Ullah ◽  
KMN Ferdous ◽  
Md Mobassar Hussain Mullick ◽  
Md Rashedul Alam ◽  
Md Sazzaduar Rahman ◽  
...  
Keyword(s):  
Amniotic Membrane ◽  
Pediatric Patients ◽  
Cost Effective ◽  
Skin Substitutes ◽  
Protein Loss ◽  
Change Rate ◽  
Partial Thickness ◽  
Partial Thickness Burn ◽  
Amnion Membrane ◽  
Dressing Change

Objective: The aim of this study was to find out the effectiveness of amniotic membrane graft dressing in the treatment of superficial partial thickness burn in children. Methods: The retrospective study was conducted on the patients admitted with superficial partial thickness burn in the burn unit of Dhaka Shishu Hospital age 0-12 years, during the period from January 1999 to December 2011. All of them treated with amnion membrane graft dressing. Results: Total 370 patients were included in this study. Mean age was 2.76 years. Amnion dressing suppresses bacteria in the wound as well as reduced infection. Amnions have good adherent characteristics, which reduced infection as well as reduction of oozing of plasma from the wound, that become dry early. It has a role on burnt pain reduction, Frequency of dressing change, rate of healing, cost, duration hospital stay. Conclusion: Our experience showed that amniotic membrane is one of the effective biological skin substitutes used in burn wounds, with efficacy of low bacterial counts, has advantageous of reducing protein loss, electrolytes & fluids. Decreasing the risk of infection minimizing pain, accelerate of wound healing and good handling properties. It is ready available does not present immunological problem and allergies response. It is cost effective and very helpful for developing countries. DOI: http://dx.doi.org/10.3329/cmoshmcj.v14i1.22875 Chatt Maa Shi Hosp Med Coll J; Vol.14 (1); Jan 2015; Page 22-25

scholarly journals New Innovations for Deep Partial-Thickness Burn Treatment with ACell MatriStem Matrix

2016 ◽  
Vol 5 (12) ◽  
pp. 546-552 ◽  
Author(s):  
Justine S. Kim ◽  
Alexander J. Kaminsky ◽  
J. Blair Summitt ◽  
Wesley P. Thayer
Keyword(s):  
Burn Treatment ◽  
Partial Thickness ◽  
Partial Thickness Burn

scholarly journals Effect of Topical Platelet-Rich Plasma on Burn Healing After Partial-Thickness Burn Injury

2016 ◽  
Vol 22 ◽  
pp. 1903-1909 ◽  
Author(s):  
Umit Ozcelik ◽  
Yahya Ekici ◽  
Huseyin Yuce Bircan ◽  
Cem Aydogan ◽  
Suna Turkoglu ◽  
...  
Keyword(s):  
Burn Injury ◽  
Platelet Rich Plasma ◽  
Partial Thickness ◽  
Partial Thickness Burn

scholarly journals miRNAs as Regulators of the Early Local Response to Burn Injuries

2021 ◽  
Vol 22 (17) ◽  
pp. 9209
Author(s):  
Ines Foessl ◽  
Christoph Walter Haudum ◽  
Ivan Vidakovic ◽  
Ruth Prassl ◽  
Joakim Franz ◽  
...  
Keyword(s):  
Early Phase ◽  
Target Genes ◽  
Burn Injury ◽  
Ex Vivo ◽  
Expression Patterns ◽  
Treatment Success ◽  
Burn Injuries ◽  
Specific Gene ◽  
Partial Thickness ◽  
Partial Thickness Burn

In burn injuries, risk factors and limitations to treatment success are difficult to assess clinically. However, local cellular responses are characterized by specific gene-expression patterns. MicroRNAs (miRNAs) are single-stranded, non-coding RNAs that regulate mRNA expression on a posttranscriptional level. Secreted through exosome-like vesicles (ELV), miRNAs are intracellular signalers and epigenetic regulators. To date, their role in the regulation of the early burn response remains unclear. Here, we identified 43 miRNAs as potential regulators of the early burn response through the bioinformatics analysis of an existing dataset. We used an established human ex vivo skin model of a deep partial-thickness burn to characterize ELVs and miRNAs in dermal interstitial fluid (dISF). Moreover, we identified miR-497-5p as stably downregulated in tissue and dISF in the early phase after a burn injury. MiR-218-5p and miR-212-3p were downregulated in dISF, but not in tissue. Target genes of the miRNAs were mainly upregulated in tissue post-burn. The altered levels of miRNAs in dISF of thermally injured skin mark them as new biomarker candidates for burn injuries. To our knowledge, this is the first study to report miRNAs altered in the dISF in the early phase of deep partial-thickness burns.

Fabrication, characterization and evaluation of the efficacy of gelatin/hyaluronic acid microporous scaffolds suffused with aloe-vera in a rat burn model

2021 ◽  
pp. 088532822110618
Author(s):  
Lalita Mehra ◽  
Smritee Mehra ◽  
Nidhi Tiwari ◽  
Thakuri Singh ◽  
Harish Rawat ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Growth Factor ◽  
Aloe Vera ◽  
Gamma Scintigraphy ◽  
Gravimetric Analysis ◽  
Burn Wounds ◽  
Partial Thickness ◽  
Partial Thickness Burn

Burn induced injuries are commonly encountered in civilian and military settings, leading to severe morbidity and mortality. Objective of this study was to construct microporous bioactive scaffolds of gelatin-hyaluronic acid suffused with aloe-vera gel (Gela/HA/AvG), and to evaluate their efficacy in healing partial-thickness burn wounds. Scaffolds were characterized using Fourier transform-infrared spectroscopy, Scanning electron microscopy, and Thermo-gravimetric analysis to understand intermolecular interactions and morphological characteristics. In-vitro fluid uptake ability and hemolytic index of test scaffolds were also determined. In-vitro collagenase digestion was done to assess biodegradability of scaffolds. Wound retraction studies were carried out in Sprague Dawley rats inflicted with partial-thickness burn wounds to assess and compare efficacy of optimized scaffolds with respect to negative and positive control groups. In-vivo gamma scintigraphy using Technetium-99m labeled Immunoglobulin-G ( 99m Tc-IgG) as imaging agent was also performed to validate efficacy results. Histological and immunohistochemical comparison between groups was also made. Scaffolds exhibited mircoporous structure, with pore size getting reduced from 41.3 ± 4.3 µm to 30.49 ± 5.7 µm when gelatin conc. was varied from 1% to 5%. Optimized test scaffolds showed sustained in-vitro swelling behavior, were biodegradable and showed hemolytic index in range of 2.4–4.3%. Wound retraction study along with in-vivo gamma scintigraphy indicated that Gela/HA/AvG scaffolds were not only able to reduce local inflammation faster but also accelerated dermis regeneration. Immunohistochemical analysis, in terms of expression levels of epidermal growth factor and fibroblast growth factor-2 also corroborated in-vivo efficacy findings. Gela/HA/AvG scaffolds, therefore, can potentially be developed into an effective dermal regeneration template for partial-thickness burn wounds.

Comparison of efficacy of silver-nanoparticle gel, nano-silver-foam and collagen dressings in treatment of partial thickness burn wounds

Burns ◽  
2019 ◽  
Vol 45 (8) ◽  
pp. 1888-1894 ◽  
Author(s):  
Miying Erring ◽  
Sunil Gaba ◽  
Subair Mohsina ◽  
Satyaswarup Tripathy ◽  
Ramesh Kumar Sharma
Keyword(s):  
Silver Nanoparticle ◽  
Nano Silver ◽  
Burn Wounds ◽  
Partial Thickness ◽  
Partial Thickness Burn

scholarly journals Solanum incanum extract enhances wound healing and tissue regeneration in burn mice model

2019 ◽  
Vol 14 (2) ◽  
pp. 101-106
Author(s):  
Zainab Qureshi ◽  
Taous Khan ◽  
Abdul Jabbar Shah ◽  
Fazli Wahid
Keyword(s):  
Wound Healing ◽  
Tissue Regeneration ◽  
Histological Analysis ◽  
Negative Control ◽  
Wound Contraction ◽  
Mice Model ◽  
Wound Area ◽  
Solanum Incanum ◽  
Partial Thickness ◽  
Partial Thickness Burn

This study was conducted to evaluate the topical efficacy of Solanum incanum for the treatment of partial-thickness burn in mice model. Mice were treated with topical ointment of S. incanum three times daily for 14 days. The wound healing was observed through wound contraction and histological parameters. The group treated with S. incanum ointment showed 81% reduction in wound area as compared to negative control where wound area reduced to 22%. The histological analysis further confirmed that ointment favors the tissue regeneration and reepithelization thus heal wound rapidly as com-pared to other groups. In conclusion, S. incanum extract enhances wound healing and tissue regeneration.

726 The Use of Xeroform Dressings for Partial Thickness Scald Burn Injuries in a Verified Pediatric Burn Center

2020 ◽  
Vol 41 (Supplement_1) ◽  
pp. S194-S195
Author(s):  
Lisa C Vitale ◽  
Jennifer Livingston ◽  
Erica Curtis ◽  
Katherine Oag ◽  
Christina M Shanti ◽  
...  
Keyword(s):  
Burn Injury ◽  
Wound Care ◽  
Total Body Surface Area ◽  
Burn Injuries ◽  
Wound Complications ◽  
Burn Wound ◽  
Burn Center ◽  
Partial Thickness ◽  
Partial Thickness Burn ◽  
At Home

Abstract Introduction For children who have suffered a burn injury one of the greatest challenges is managing pain with an adequate yet practical burn wound dressing that will ultimately be managed at home. Medical product companies have created a variety of wound care products available on the market. These products are advertised to be more superior over one another in categories such as decrease in wound infections, minimization of pain, ease of dressing application, increased dressing wear time, and better wound healing. With all the options for burn wound care there are many factors to consider when choosing a burn dressing such as cost, ease of dressing for families at home, comfort, and efficacy. At our ten year verified pediatric burn center we have tried many different burn wound care products, however we have found Xeroform and bacitracin to be the most practical and easy to use for our patient population. Methods A retrospective chart review was performed from 2016–2018 of all cascading scald injuries to children 0–5 years of age treated at our verified pediatric burn center. 179 patients were included in this review. Of those patients a total of 52 patients were excluded, 28 patients had no follow up, 21 patients received alternate dressings, and 3 patients had full thickness injuries requiring a split thickness skin graft (STSG). Charts were reviewed for total body surface area (TBSA), length of stay (LOS), discharge dressing type, complications, and time to healing. All patients included routinely received consistent application of the Xeroform and bacitracin. Results 127 patients discharged with Xeroform dressings were included in this study with an average age of 1.4 years old (range 0–5 years) and average TBSA of 2.5% (range 0.25–13%). The average LOS was 1.6 days (range 1–10 days). In this sample 32 (25%) patients were healed within 7 days. 77 (61%) patients were healed within 7–14 days. 11 (9%) patients were healed within 14–21 days. 7 (5%) patients were healed in greater than 21 days. There were no wound complications identified within this study group. Conclusions Using Xeroform as our standard of practice has streamlined the care provided to our patients. We have demonstrated consistent effective re-epithelization, protection from infection, and ease of dressings for families and burn providers. In our experience Xeroform has provided a versatile way to care for partial thickness burn injuries. Applicability of Research to Practice We suggest Xeroform and bacitracin dressings be used for partial thickness burn injuries in patients under 5 years of age. This dressing may be superior to other products because it allows for bathing while providing good wound epithelization and is easy to use.

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