International testicular cancer incidence rates in children, adolescents and young adults

Abstract Background Studies have documented a temporal increase in incidence for several cancers in US young adults aged 25 to 39-years, including noncardia gastric cancer, colorectal cancer, and distant-stage breast cancer. To further characterize trends in young adults, we assessed age-specific and stage-specific incidence trends from 1975 to 2015, overall (all malignant cancers combined), and for 18 and 16 cancer sites in women and men, respectively. Methods We used US population-based data from the Surveillance, Epidemiology, and End Results Program to obtain overall and site-specific cancer incidence rates by sex and age group. We individually analyzed cancer sites with an incidence rate of at least 5 per 100 000 in 2015, accounting for greater than 90% of all cancer diagnoses. We estimated annual percent changes (APCs) using segment log-linear regression performed with joinpoint software; multiple permutation testing was used to identify inflection points. We forecasted overall cancer incidence through 2030 using age-period-cohort regression models. Results Based on trends occurring after the most recent joinpoint inflection point, overall cancer incidence increased by 1.15% (95% CI = 1.01% to 1.28%) per year in 25- to 39-year-old women and by 0.46% (95% CI = 0.17% to 0.75%) per year in 25- to 39-year-old men; APCs were of much lower magnitude in the older age groups (eg, 70- to 84-year-old women APC = −0.31%, 95% CI = −0.42% to −0.20%). We forecasted that overall cancer incidence will increase by an additional 11% by 2030 in 25- to 39-year-old women, and by an additional 12% in 25- to 39-year-old men. Ten of the 18 cancers assessed in 25- to 39-year-old women and 7 of the 16 cancers in 25- to 39-year-old men have been statistically significantly increasing over time. We found that the increase in incidence for young adults is stage specific for some cancers (eg, only nonlocalized breast cancer has increased in 25- to 39-year-old women). Conclusion Cancer incidence is increasing in young adults, particularly in young women.

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Time Series Analysis and Prediction on Cancer Incidence Rates

Journal of Medical Discovery ◽

10.24262/jmd.2.3.17030 ◽

2017 ◽

Vol 2 (3) ◽

Author(s):

Liming Xie ◽

Keyword(s):

Time Series ◽

Time Series Analysis ◽

Cancer Incidence ◽

Incidence Rates ◽

Series Analysis ◽

Cancer Incidence Rates

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Faculty Opinions recommendation of Age-related crossover in breast cancer incidence rates between black and white ethnic groups.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1137991.595098 ◽

2008 ◽

Author(s):

Ellen Chang

Keyword(s):

Breast Cancer ◽

Ethnic Groups ◽

Cancer Incidence ◽

Breast Cancer Incidence ◽

Incidence Rates ◽

Black And White ◽

Age Related ◽

White Ethnic ◽

Cancer Incidence Rates

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Prevalence-corrected Prostate Cancer Incidence Rates and Trends

American Journal of Epidemiology ◽

10.1093/aje/155.2.148 ◽

2002 ◽

Vol 155 (2) ◽

pp. 148-152 ◽

Cited By ~ 11

Author(s):

R. M. Merrill

Keyword(s):

Prostate Cancer ◽

Cancer Incidence ◽

Incidence Rates ◽

Prostate Cancer Incidence ◽

Cancer Incidence Rates

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Influence of Diet and Tobacco Smoking on Pancreatic Cancer Incidence in Poland in 1960–2008

Gastroenterology Research and Practice ◽

10.1155/2012/682156 ◽

2012 ◽

Vol 2012 ◽

pp. 1-9 ◽

Cited By ~ 8

Author(s):

Mirosław Jarosz ◽

Włodzimierz Sekuła ◽

Ewa Rychlik

Keyword(s):

Pancreatic Cancer ◽

Cancer Incidence ◽

Tobacco Smoking ◽

Red Meat ◽

Incidence Rates ◽

Dietary Factors ◽

Balance Sheets ◽

Animal Fats ◽

The Relationship ◽

Cancer Incidence Rates

The aim of the study was to investigate the relationship between pancreatic cancer incidence and selected dietary factors, alcohol consumption, and tobacco smoking in Poland in 1960–2008. Data on pancreatic cancer morbidity were derived from the National Cancer Registry and on food consumption from the national food balance sheets. In 1960–1989 correlations were found between pancreatic cancer incidence rates and energy (0.60 for males and 0.57 for females), cholesterol (0.87 and 0.80), fibre (−0.84 and −0.89) and folate (−0.45 and −0.49) intake, the consumption of total fats (0.94 and 0.91), animal fats (0,90 and 0,82), sugar (0.88 and 0.87), cereals (−0.93 and −0.91), and alcohol (0.86 and 0.82). In 1990–2008 morbidity correlated with the consumption of red meat (0.67 and 0.48), poultry (−0.88 and −0.57), and fruit (−0.62 and −0.50). Correlation with tobacco smoking was observed in the whole studied period (0.55 and 0.44). Increased incidence of pancreatic cancer in 1960–1995 was probably related to adverse dietary patterns up to 1989, especially high consumption of fats, sugar, and alcohol. Further positive changes in the diet such as lowering red meat consumption and increasing fruit consumption could influence incidence reduction in recent years. Also changes in tobacco smoking could affect the morbidity.

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