Dual blockade of phosphatidylinositol 3′-kinase and mitogen-activated protein kinase pathways overcomes paclitaxel-resistance in colorectal cancer

Paclitaxel Resistance ◽

Dual Blockade ◽

Clinical Validation of Coexisting Activating Mutations Within EGFR, Mitogen-Activated Protein Kinase, and Phosphatidylinositol 3-Kinase Pathways in Lung Cancers

Archives of Pathology & Laboratory Medicine ◽

10.5858/arpa.2017-0495-oa ◽

2019 ◽

Vol 143 (2) ◽

pp. 174-182 ◽

Cited By ~ 6

Author(s):

Federico De Marchi ◽

Lisa Haley ◽

Henderson Fryer ◽

Junaid Ibrahim ◽

Katie Beierl ◽

...

Keyword(s):

Protein Kinase ◽

Clinical Validation ◽

Lung Cancers ◽

Activating Mutations ◽

Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation.

Journal of Biological Chemistry ◽

10.1074/s0021-9258(19)67421-1 ◽

2001 ◽

Vol 272 (5) ◽

pp. 3124

Author(s):

Shuko Harada ◽

Robert M. Smith ◽

Judith A. Smith ◽

Morris F. White ◽

Leonard Jarett

Keyword(s):

Protein Kinase ◽

Insulin Receptor ◽

Insulin Receptor Substrate ◽

Insulin Receptor Substrate 1 ◽

Kinase Activation ◽

Fos Expression ◽

Betacellulin induces angiogenesis through activation of mitogen‐activated protein kinase and phosphatidylinositol 3’‐kinase in endothelial cells

The FASEB Journal ◽

10.1096/fj.02-0570fje ◽

2002 ◽

Vol 17 (2) ◽

pp. 318-320 ◽

Cited By ~ 50

Author(s):

Hoe Suk Kim ◽

Hyoung Seek Shin ◽

Hee Jin Kwak ◽

Chung‐Hyun Cho ◽

Chin O. Lee ◽

...

Keyword(s):

Endothelial Cells ◽

Protein Kinase ◽

Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-07-2060 ◽

2008 ◽

Vol 7 (4) ◽

pp. 915-922 ◽

Cited By ~ 48

Author(s):

Maria Serova ◽

Aïda Ghoul ◽

Karim A. Benhadji ◽

Sandrine Faivre ◽

Christophe Le Tourneau ◽

...

Keyword(s):

Protein Kinase C ◽

Protein Kinase ◽

Cancer Cells ◽

Kinase Signaling ◽

Kinase C ◽

Simultaneous inhibition of the mitogen-activated protein kinase kinase and phosphatidylinositol 3'-kinase pathways enhances sensitivity to paclitaxel in ovarian carcinoma

Cancer Science ◽

10.1111/j.1349-7006.2007.00624.x ◽

2007 ◽

Vol 98 (12) ◽

pp. 2002-2008 ◽

Cited By ~ 10

Author(s):

Wakae Kawaguchi ◽

Hiroaki Itamochi ◽

Junzo Kigawa ◽

Yasunobu Kanamori ◽

Tetsuro Oishi ◽

...

Keyword(s):

Protein Kinase ◽

Ovarian Carcinoma ◽

Simultaneous Inhibition ◽

Protein Kinase Kinase ◽

Insulin Growth Factor-2 Binding Protein 3 (IGF2BP3) Is a Glioblastoma-specific Marker That Activates Phosphatidylinositol 3-Kinase/Mitogen-activated Protein Kinase (PI3K/MAPK) Pathways by Modulating IGF-2

Journal of Biological Chemistry ◽

10.1074/jbc.m110.178012 ◽

2011 ◽

Vol 286 (29) ◽

pp. 25882-25890 ◽

Cited By ~ 81

Author(s):

Ramaswamy Suvasini ◽

Bhargava Shruti ◽

Balaram Thota ◽

Sridevi Vijay Shinde ◽

Dinorah Friedmann-Morvinski ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Binding Protein ◽

Specific Marker ◽

Insulin Growth Factor ◽

Mapk Pathways ◽

Clinical Validation of Coexisting Activating Mutations Within EGFR, Mitogen-Activated Protein Kinase, and Phosphatidylinositol 3-Kinase Pathways in Lung Cancers

Archives of Pathology & Laboratory Medicine ◽

10.5858/arpa.2018-0495-oa ◽

2018 ◽

Cited By ~ 1

Author(s):

Federico De Marchi ◽

Lisa Haley ◽

Henderson Fryer ◽

Junaid Ibrahim ◽

Katie Beierl ◽

...

Keyword(s):

Protein Kinase ◽

Clinical Validation ◽

Lung Cancers ◽

Activating Mutations ◽

Activation of Fatty Acid Synthesis during Neoplastic Transformation: Role of Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase

Experimental Cell Research ◽

10.1006/excr.2002.5600 ◽

2002 ◽

Vol 279 (1) ◽

pp. 80-90 ◽

Cited By ~ 128

Author(s):

Y Yang

Keyword(s):

Fatty Acid ◽

Protein Kinase ◽

Fatty Acid Synthesis ◽

Neoplastic Transformation ◽

Acid Synthesis ◽

Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase

Journal of Neurochemistry ◽

10.1111/j.1471-4159.2006.03827.x ◽

2006 ◽

Vol 97 (4) ◽

pp. 1191-1202 ◽

Cited By ~ 74

Author(s):

Yumiko Numakawa ◽

Tadahiro Numakawa ◽

Tomoya Matsumoto ◽

Yuki Yagasaki ◽

Emi Kumamaru ◽

...

Keyword(s):

Oxidative Stress ◽

Cell Death ◽

Vitamin E ◽

Protein Kinase ◽

Cortical Neurons ◽

Cultured Cortical Neurons ◽

Involvement of a phosphatidylinositol 3-kinase–p38 mitogen activated protein kinase pathway in antigen-induced IL-4 production in mast cells

Biochimica et Biophysica Acta (BBA) - Bioenergetics ◽

10.1016/s0005-2728(99)00104-8 ◽

2000 ◽

Vol 1456 (1) ◽

pp. 45-55 ◽

Cited By ~ 34

Author(s):

Noriyasu Hirasawa ◽

Yukako Sato ◽

Yuhko Fujita ◽

Kazuo Ohuchi

Keyword(s):

Mast Cells ◽

Protein Kinase ◽

Kinase Pathway ◽