scholarly journals Circulating matrix metalloproteinase-8 (MMP-8) and MMP-9 are increased in chronic periodontal disease and decrease after non-surgical periodontal therapy

2009 ◽  
Vol 409 (1-2) ◽  
pp. 117-122 ◽  
Author(s):  
Andrea M. Marcaccini ◽  
Arthur B. Novaes ◽  
Cesar A. Meschiari ◽  
Sergio L. Souza ◽  
Daniela B. Palioto ◽  
...  
Keyword(s):  
Matrix Metalloproteinase ◽  
Periodontal Disease ◽  
Periodontal Therapy ◽  
Chronic Periodontal Disease

scholarly journals Effects of Nonsurgical Periodontal Therapy on Clinical Response, Microbiological Profile, and Glycemic Control in Malaysian Subjects with Type 1 Diabetes

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Samira Mukhtar Buzinin ◽  
Aied Mohammed Alabsi ◽  
Alexander Tong Boon Tan ◽  
Vui King Vincent-Chong ◽  
Dasan Swaminathan
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Periodontal Disease ◽  
Test Group ◽  
Periodontal Therapy ◽  
Control Group ◽  
Chronic Periodontal Disease ◽  
Nonsurgical Periodontal Therapy ◽  
Significant Difference

The association between diabetes mellitus and chronic periodontal disease has long been established. Most of the researches linking these two very common chronic diseases were based on type 2 diabetes mellitus and chronic periodontal disease. However, this study was conducted to investigate the association between type 1 diabetes and chronic periodontal disease in Malaysian subjects. Forty-one Malaysian subjects, of which 20 subjects were type 1 diabetics and with chronic periodontal disease (test group) and 21 subjects with only chronic periodontal disease (control group), were included in the study. Periodontal parameters and plaque samples for microbiological evaluation were done at baseline, 2 and 3 months after nonsurgical periodontal therapy. Blood samples were taken from only the test group and evaluated for HbA1c at baseline and 3 months after periodontal therapy. There were no statistically significant difference in periodontal parameters between groups (P>0.05) and no significant improvement in the level of HbA1c in the test group. Microbiological studies indicated that there were significant reductions in the levels of the tested pathogens in both groups. The results of our study were similar to the findings of several other studies that had been done previously.

scholarly journals Incidence of the Acute Symptom of Chronic Periodontal Disease in Patients Undergoing Supportive Periodontal Therapy: A 5-Year Study Evaluating Climate Variables

2019 ◽  
Vol 16 (17) ◽  
pp. 3070
Author(s):  
Hikari Saho ◽  
Noriko Takeuchi ◽  
Daisuke Ekuni ◽  
Manabu Morita
Keyword(s):  
Periodontal Disease ◽  
Barometric Pressure ◽  
Periodontal Therapy ◽  
Climate Variables ◽  
Climate Data ◽  
Local Climate ◽  
Periodontal Condition ◽  
Acute Symptom ◽  
Chronic Periodontal Disease ◽  
Supportive Periodontal Therapy

Although patients under supportive periodontal therapy (SPT) have a stable periodontal condition, the acute symptom of chronic periodontal disease occasionally occurs without a clear reason. Therefore, in the present study, to obtain a better understanding of this relationship in patients undergoing SPT, we hypothesized that the acute symptom of chronic periodontal disease might be affected by climate factors. We conducted a questionnaire study and carried out oral examinations on patients undergoing SPT who had been diagnosed as having the acute symptom of chronic periodontal disease. We collected climate data from the local climate office in Okayama city, Japan. We predicted parameters that affect the acute symptom of chronic periodontal disease with unidentified cause and divided patients into high and low groups in terms of climate predictors. Then we defined the cut-off values of parameters showing significant differences in the incidence of the acute symptom of chronic periodontal disease. The incidence of the acute symptom of chronic periodontal disease with unidentified cause was significantly different when the cases were classified according to the maximum hourly decrease in barometric pressure (1.5 and 1.9 hPa) (p = 0.04 and p = 0.03, respectively). This suggests that climate variables could be predictors of the acute symptom of chronic periodontal disease. Therefore, gaining a better understanding of these factors could help periodontal patients undergoing SPT prepare to avoid the acute symptom of chronic periodontal disease.

Effects of periodontal therapy with topical antibiotics in the glycemic control of diabetic patients: systematic review.

2019 ◽  
Vol 27 (1) ◽  
pp. 31-42
Author(s):  
Gloria Cristina Aranzazu-Moya
Keyword(s):  
Periodontal Disease ◽  
Periodontal Therapy ◽  
Periodontal Treatment ◽  
Diabetic Patients ◽  
Inclusion Criteria ◽  
Topical Antibiotics ◽  
Bias Risk ◽  
Black Scale ◽  
Glycated Hemoglobin A ◽  
Modest Reduction

Background: Periodontal disease is considered as a diabetes complication and has been suggested that periodontal treatment plus antibiotics should reduce glycated hemoglobin A, by reducing local production of pro inflammatory substances. Objective: To evaluate diabetic patients with periodontal disease under periodontal treatment plus topical antibiotics and reduction of  HbA1c, compared to diabetic patients under periodontal treatment without antibiotics. Materials and Methods: Using PUBMED, SCOPUS, WEB OF SCIENCE, EMBASE and Google Scholar data bases, were screened documents from 2008 to 2018. The documents included were the clinical studies, which included non-surgical periodontal treatment plus topical antibiotics, whose outcomes included the HbA1c report. Two independent researchers evaluate title; abstract and bias risk with Downs Black scale and Cochrane tool. Documents with a score higher than 15 on average by the two evaluators were included. Results: Five articles, which find inclusion criteria, were identified. Two documents failed to demonstrate statistically significant effect when compared to non-surgical periodontal therapy alone. Conclusion: In general a modest reduction of HbA1c was identified when using antibiotic therapy.

scholarly journals Relation between chronic periodontal disease and plasmatic levels of triglycerides, total cholesterol and fractions

2005 ◽  
Vol 19 (4) ◽  
pp. 284-289 ◽  
Author(s):  
Ana Cristina Posch Machado ◽  
Maria Rozeli de Souza Quirino ◽  
Luiz Fernando Costa Nascimento
Keyword(s):  
Periodontal Disease ◽  
Total Cholesterol ◽  
Blood Lipid ◽  
Oral Disease ◽  
Whole Body ◽  
Lipid Levels ◽  
Periodontal Infection ◽  
Chronic Periodontal Disease ◽  
Systemic Health ◽  
Blood Lipid Levels

Many people in the world are affected by hyperlipidemia, which is a known risk factor for atherosclerotic disease. On the other hand, periodontitis, a prevalent oral disease, has been connected to several systemic health changes, including an altered lipid metabolism. Transient and recurrent bacteremias, which may be caused by periodontal infection, induce an intense local and systemic inflammatory response, leading to changes in the whole body. The aim of the present study was to verify the relationship between severe and moderate periodontal disease and blood lipid levels. Sixty individuals seen at the clinics of the University of Taubaté, São Paulo, over 20 years old, were divided into two groups, with and without periodontitis, and paired according to sex and age. Their levels of total cholesterol, tryglicerides and fractions were determined. Variables related to high cholesterol levels, including age, sex and body mass index, were evaluated. The values recommended by the Brazilian Society of Cardiology were considered to classify lipidemia. The results showed that mean levels of cholesterol (192.1 mg/dl ± 40.9) and triglycerides (153.5 mg/dl ± 105.6) in individuals with periodontitis were higher than, but not statistically different from, those of individuals without periodontitis (186.1 mg/dl ± 35.4 and 117.5 mg/dl ± 68, respectively). Therefore, this study has demonstrated that there is no significant relationship between periodontal disease, regardless of its intensity, and blood lipid levels in the studied population.

Matrix metalloproteinase-8 levels in periodontal disease patients: A systematic review

2017 ◽  
Vol 53 (2) ◽  
pp. 156-163 ◽  
Author(s):  
E. F. de Morais ◽  
J. C. Pinheiro ◽  
R. B. Leite ◽  
P. P. A. Santos ◽  
C. A. G. Barboza ◽  
...  
Keyword(s):  
Systematic Review ◽  
Matrix Metalloproteinase ◽  
Periodontal Disease

scholarly journals Association between chronic periodontal disease and cardiovascular risk factor hyperlipidemia

2014 ◽  
Vol 3 (4) ◽  
pp. 249 ◽  
Author(s):  
Anitha Akkaloori ◽  
Parthasarathi Parthasarathi ◽  
MohammadShakeel Anjum ◽  
Praveen Gadde ◽  
Monica Mocherla ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cardiovascular Risk ◽  
Periodontal Disease ◽  
Cardiovascular Risk Factor ◽  
Chronic Periodontal Disease

scholarly journals Failures in periodontal therapy

1970 ◽  
Vol 9 (4) ◽  
pp. 193-198
Author(s):  
KD Jithendra ◽  
A Bansali ◽  
SS Ramachandra
Keyword(s):  
Risk Factors ◽  
Periodontal Disease ◽  
Treatment Options ◽  
Medical Science ◽  
Treatment Strategies ◽  
Periodontal Therapy ◽  
Plaque Control ◽  
Natural Dentition ◽  
Oral Hygiene Instructions ◽  
Biomechanical Factors

Studies have shown that modern periodontal therapies are effective in maintaining a healthy natural dentition as well as controlling periodontal disease. Numerous treatment strategies and various techniques have been designed & described to treat periodontal disease. Most of these procedures had drawbacks which were identified, leading to the modifications of the original techniques which lead to better treatment options, but still very less emphasis has been laid on failures. Without a regular program of clinical re-evaluation, plaque control, oral hygiene instructions, and reassessment of biomechanical factors the benefits of treatment are often lost and inflammatory disease in the form of recurrent periodontitis may result. So, this review describes the most common failures noticed in periodontal therapies and also discusses the possible solutions to reduce the incidence of failures in periodontal therapy.Key words: Periodontal therapy; risk factors; failures.DOI: 10.3329/bjms.v9i4.6680Bangladesh Journal of Medical Science Vol.09 No.4 July 2010 pp.193-198

Evaluation of the effectiveness of professional hygiene results in patients with diabetes mellitus type I and overweight

2021 ◽  
Vol 26 (1) ◽  
pp. 20-27
Author(s):  
E. S. Loboda ◽  
L. Yu. Orekhova ◽  
E. V. Grinenko ◽  
A. Yu. Kropotina ◽  
N. A. Iamanidze ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Periodontal Disease ◽  
Oral Hygiene ◽  
Periodontal Therapy ◽  
Diabetes Mellitus Type ◽  
Comprehensive Treatment ◽  
Type I ◽  
Diabetes Mellitus Type I ◽  
Patients With Diabetes

Relevance. At present, the problem of the prevalence of overweight is becoming increasingly important in countries with a high standard of living, especially among the urban population. The social significance of this problem is determined by the threat of the development of diseases of the cardiovascular system, gastrointestinal tract, musculoskeletal system, as well as diabetes mellitus, which in turn are serious risk factors for the development and progression of periodontal pathology. One of the stages in the treatment of periodontal diseases is professional oral hygiene, the tactics of which, the effectiveness and stability of the results obtained also depend on taking into account the individual characteristics of the organism. Objective – to assess the effect of overweight (ICD 10 - K63.5) on the manifestation of periodontal disease and the clinical effectiveness of professional oral hygiene as a stage of initial periodontal therapy in the presence of diabetes mellitus. Materials and methods. The study involved 83 patients with diabetes mellitus type I aged 25 to 45 years with overweight and normal constitution, with chronic generalized periodontitis of mild and moderate severity. All patients underwent a standard complex of professional oral hygiene. Re-examination was carried out after 1 month. Results. The severity of clinical manifestations of periodontitis in patients with diabetes mellitus and overweight was higher than in the group of patients with normal constitution. The analysis of the effectiveness of professional oral hygiene as one of the stages of conservative periodontal therapy revealed differences in the response from the organism as a whole, and periodontal tissues in particular in the examined groups, demonstrating the pathological effect of excess body weight on the decrease in the effectiveness of hygiene measures. Conclusion. The identification of differences in the examined groups confirms the importance of overweight as an aggravating component in patients with periodontal disease and diabetes mellitus type I and dictates the need for a more detailed study of this parameter in the management of patients in this group and predicting treatment results, as well as creates the need for development and implementation of a comprehensive treatment and prevention strategy, including the assessment and monitoring of body mass index, promotion of a healthy lifestyle, elimination of modifiable risk factors.

Sign in / Sign up

Export Citation Format

Share Document