The effect of vitamin E supplementation on antioxidant enzyme activities and lipid peroxidation levels in hemodialysis patients

2003 ◽  
Vol 338 (1-2) ◽  
pp. 91-98 ◽  
Author(s):  
Belma Giray ◽  
Erdal Kan ◽  
Musa Bali ◽  
Filiz Hincal ◽  
Nursen Basaran
2002 ◽  
Vol 3 (3) ◽  
pp. 185-192 ◽  
Author(s):  
Randall L. Davis ◽  
Christy L. Lavine ◽  
Melissa A. Arredondo ◽  
Patrick McMahon ◽  
Thomas E. Tenner, Jr.

Determination of reliable bioindicators of diabetes-induced oxidative stress and the role of dietary vitamin E supplementation were investigated. Blood (plasma) chemistries, lipid peroxidation (LPO), and antioxidant enzyme activities were measured over 12 weeks in New Zealand White rabbits (control, diabetic, and diabetic + vitamin E). Cholesterol and triglyceride levels did not correlate with diabetic state. PlasmaLPOwas influenced by diabetes and positively correlated with glucose concentration only, not cholesterol or triglycerides. Liver glutathione peroxidase (GPX) activity negatively correlated with glucose and triglyceride levels. Plasma and erythrocyte GPX activities positively correlated with glucose, cholesterol, and triglyceride concentrations. Liver superoxide dismutase activity positively correlated with glucose and cholesterol concentration. Vitamin E reduced plasma LPO, but did not affect the diabetic state. Thus, plasmaLPOwas the most reliable indicator of diabetes-induced oxidative stress. Antioxidant enzyme activities and types of reactive oxygen species generated were tissue dependent. Diabetes-induced oxidative stress is diminished by vitamin E supplementation.


Author(s):  
Krzysztof Gwoździński ◽  
Marta Gonciarz ◽  
Ewa Kilańczyk ◽  
Aleksandra Kowalczyk ◽  
Anna Pieniążek ◽  
...  

Antioxidant enzyme activities and lipid peroxidation inIn the present work we have studied some of the indicators of oxidative damage of the digestive gland tissue of two populations of mussels


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