Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis

Cell Reports ◽

10.1016/j.celrep.2021.109870 ◽

2021 ◽

Vol 37 (3) ◽

pp. 109870

Author(s):

Shanshan Duan ◽

Loredana Moro ◽

Rui Qu ◽

Daniele Simoneschi ◽

Hyunwoo Cho ◽

...

Keyword(s):

Akt Signaling ◽

Prostate Tumorigenesis

Download Full-text

KDM5B Is Essential for the Hyperactivation of PI3K/AKT Signaling in Prostate Tumorigenesis

Cancer Research ◽

10.1158/0008-5472.can-20-0505 ◽

2020 ◽

Vol 80 (21) ◽

pp. 4633-4643

Author(s):

Guoliang Li ◽

Thanigaivelan Kanagasabai ◽

Wenfu Lu ◽

Mike R. Zou ◽

Shang-Min Zhang ◽

...

Keyword(s):

Akt Signaling ◽

Prostate Tumorigenesis

Download Full-text

Ionizing Radiation Enhances Matrix Metalloproteinase-2 Secretion and Invasion of Glioma Cells through Src/Epidermal Growth Factor Receptor-Mediated p38/Akt and Phosphatidylinositol 3-Kinase/Akt Signaling Pathways

Yearbook of Pathology and Laboratory Medicine ◽

10.1016/s1077-9108(08)70678-9 ◽

2008 ◽

Vol 2008 ◽

pp. 231-233

Author(s):

C. Horbinski

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Matrix Metalloproteinase ◽

Growth Factor Receptor ◽

Glioma Cells ◽

Akt Signaling ◽

Matrix Metalloproteinase 2 ◽

Phosphatidylinositol 3 Kinase ◽

Epidermal Growth

Download Full-text

Faculty Opinions recommendation of Human chorionic gonadotropin stimulates trophoblast invasion through extracellularly regulated kinase and AKT signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1115242.571244 ◽

2008 ◽

Author(s):

John Aplin

Keyword(s):

Chorionic Gonadotropin ◽

Human Chorionic Gonadotropin ◽

Akt Signaling ◽

Trophoblast Invasion

Download Full-text

Faculty Opinions recommendation of Stromal fibroblast-derived miR-409 promotes epithelial-to-mesenchymal transition and prostate tumorigenesis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718509913.793498204 ◽

2014 ◽

Author(s):

Simon Hayward

Keyword(s):

Epithelial To Mesenchymal Transition ◽

Stromal Fibroblast ◽

Prostate Tumorigenesis ◽

Mesenchymal Transition

Download Full-text

Faculty Opinions recommendation of SPOP Mutation Drives Prostate Tumorigenesis In Vivo through Coordinate Regulation of PI3K/mTOR and AR Signaling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727407719.793532416 ◽

2017 ◽

Author(s):

Nicholas Leslie

Keyword(s):

Prostate Tumorigenesis ◽

Coordinate Regulation

Download Full-text

Faculty Opinions recommendation of Rpn10 promotes tumor progression by regulating hypoxia-inducible factor 1 alpha through the PTEN/Akt signaling pathway in hepatocellular carcinoma.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.734911165.793580826 ◽

2020 ◽

Author(s):

Leonardo Salmena

Keyword(s):

Hepatocellular Carcinoma ◽

Tumor Progression ◽

Signaling Pathway ◽

Hypoxia Inducible Factor ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Hypoxia Inducible Factor 1

Download Full-text

Faculty Opinions recommendation of Loss of PDZK1 expression activates PI3K/AKT signaling via PTEN phosphorylation in gastric cancer.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.735438256.793580821 ◽

2020 ◽

Author(s):

Leonardo Salmena

Keyword(s):

Gastric Cancer ◽

Download Full-text

Effects of deguelin on proliferation and apoptosis of MCF-7 breast cancer cells by phosphatidylinositol 3-kinase/Akt signaling pathway

Journal of Chinese Integrative Medicine ◽

10.3736/jcim20110511 ◽

2011 ◽

Vol 9 (5) ◽

pp. 533-538 ◽

Author(s):

ZH Chu

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Signaling Pathway ◽

Breast Cancer Cells ◽

Akt Signaling ◽

Akt Signaling Pathway ◽

Phosphatidylinositol 3 Kinase ◽

Proliferation And Apoptosis ◽

Mcf 7 ◽

Phosphatidylinositol 3

Download Full-text

Functional Interaction between Rb and Thoc1 in Mouse Prostate Tumorigenesis

10.21236/ada548020 ◽

2011 ◽

Author(s):

Meenalakshmi Chinnam

Keyword(s):

Functional Interaction ◽

Prostate Tumorigenesis ◽

Download Full-text

Breast Cancer Chemoresistance Mechanisms Through PI 3-Kinase and Akt Signaling

10.21236/ada608893 ◽

2014 ◽

Author(s):

Alex Toker ◽

Kristin Brown

Keyword(s):

Breast Cancer ◽

Akt Signaling ◽

Cancer Chemoresistance

Download Full-text