Role of cerium oxide nanoparticles in improving oxidative stress and developmental delays in Drosophila melanogaster as an in-vivo model for bisphenol a toxicity

Chemosphere ◽  
2021 ◽  
pp. 131363
Author(s):  
Arkajyoti Sarkar ◽  
Tharun Selvam Mahendran ◽  
Aasha Meenakshisundaram ◽  
Rushenka Vashti Christopher ◽  
Pallavi Dan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Drosophila Melanogaster ◽  
Bisphenol A ◽  
Cerium Oxide ◽  
Developmental Delays ◽  
Cerium Oxide Nanoparticles ◽  
In Vivo Model ◽  
Oxide Nanoparticles

Drosophila melanogaster as an in vivo model to study the potential toxicity of cerium oxide nanoparticles

2019 ◽  
Vol 490 ◽  
pp. 70-80 ◽  
Author(s):  
Vignesh Sundararajan ◽  
Pallavi Dan ◽  
Ajay Kumar ◽  
G. Devanand Venkatasubbu ◽  
Sahoko Ichihara ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Cerium Oxide ◽  
Cerium Oxide Nanoparticles ◽  
In Vivo Model ◽  
Oxide Nanoparticles ◽  
Potential Toxicity

scholarly journals In Vitro and In Vivo Antioxidant Activity of the New Magnetic-Cerium Oxide Nanoconjugates

Nanomaterials ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 1565 ◽  
Author(s):  
Turin-Moleavin ◽  
Fifere ◽  
Lungoci ◽  
Rosca ◽  
Coroaba ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Iron Oxide ◽  
Cerium Oxide ◽  
Chemical Activation ◽  
Radical Scavenging ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles

Background. Cerium oxide nanoparticles present the mimetic activity of superoxide dismutase, being able to inactivate the excess of reactive oxygen species (ROS) correlated with a large number of pathologies, such as stents restenosis and the occurrence of genetic mutations that can cause cancer. This study presents the synthesis and biological characterisation of nanoconjugates based on nanoparticles of iron oxide interconnected with cerium oxide conjugates. Methods. The synthesis of magnetite-nanoceria nanoconjugates has been done in several stages, where the key to the process is the coating of nanoparticles with polyethyleneimine and its chemical activation-reticulation with glutaraldehyde. The nanoconjugates are characterised by several techniques, and the antioxidant activity was evaluated in vitro and in vivo. Results. Iron oxide nanoparticles interconnected with cerium oxide nanoparticles were obtained, having an average diameter of 8 nm. Nanoconjugates prove to possess superparamagnetic properties and the saturation magnetisation varies with the addition of diamagnetic components in the system, remaining within the limits of biomedical applications. In vitro free-radical scavenging properties of nanoceria are improved after the coating of nanoparticles with polyethylenimine and conjugation with magnetite nanoparticles. In vivo studies reveal increased antioxidant activity in all organs and fluids collected from mice, which demonstrates the ability of the nanoconjugates to reduce oxidative stress. Conclusion. Nanoconjugates possess magnetic properties, being able to scavenge free radicals, reducing the oxidative stress. The combination of the two properties mentioned above makes them excellent candidates for theranostic applications.

Role of Cerium Oxide Nanoparticles in a Paraquat-Induced Model of Oxidative Stress: Emergence of Neuroprotective Results in the Brain

2018 ◽  
Vol 66 (3) ◽  
pp. 420-427 ◽  
Author(s):  
Akram Ranjbar ◽  
Sara Soleimani Asl ◽  
Farzin Firozian ◽  
Hamid Heidary Dartoti ◽  
Saman Seyedabadi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cerium Oxide ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
The Brain

scholarly journals Role of trivalent La and Nd dopants in lattice distortion and oxygen vacancy generation in cerium oxide nanoparticles

2006 ◽  
Vol 88 (24) ◽  
pp. 243110 ◽  
Author(s):  
Swanand Patil ◽  
Sudipta Seal ◽  
Yu Guo ◽  
Alfons Schulte ◽  
John Norwood
Keyword(s):  
Oxygen Vacancy ◽  
Cerium Oxide ◽  
Lattice Distortion ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Vacancy Generation

Cerium oxide nanoparticles protects against acrylamide induced toxicity in HepG2 cells through modulation of oxidative stress

2018 ◽  
Vol 42 (1) ◽  
pp. 54-59 ◽  
Author(s):  
Aala Azari ◽  
Mohammad Shokrzadeh ◽  
Ehsan Zamani ◽  
Nahid Amani ◽  
Fatemeh Shaki
Keyword(s):  
Oxidative Stress ◽  
Cerium Oxide ◽  
Hepg2 Cells ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles

scholarly journals Role of epithelial-mesenchymal transition (EMT) and fibroblast function in cerium oxide nanoparticles-induced lung fibrosis

2017 ◽  
Vol 323 ◽  
pp. 16-25 ◽  
Author(s):  
Jane Ma ◽  
Bridget Bishoff ◽  
R.R. Mercer ◽  
Mark Barger ◽  
Diane Schwegler-Berry ◽  
...  
Keyword(s):  
Cerium Oxide ◽  
Lung Fibrosis ◽  
Epithelial Mesenchymal Transition ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Mesenchymal Transition

Cerium oxide nanoparticles alleviate oxidative stress and decreases Nrf-2/HO-1 in D-GALN/LPS induced hepatotoxicity

2015 ◽  
Vol 73 ◽  
pp. 80-86 ◽  
Author(s):  
Reem M. Hashem ◽  
Laila A. Rashd ◽  
Khalid S. Hashem ◽  
Hatem M. Soliman
Keyword(s):  
Oxidative Stress ◽  
Cerium Oxide ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles

Role of phosphate on stability and catalase mimetic activity of cerium oxide nanoparticles

2015 ◽  
Vol 132 ◽  
pp. 78-84 ◽  
Author(s):  
Ragini Singh ◽  
Sanjay Singh
Keyword(s):  
Cerium Oxide ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles
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