A RARE CASE OF PULMONARY PARENCHYMAL INVOLVEMENT OF MULTIPLE MYELOMA

CHEST Journal ◽  
2019 ◽  
Vol 156 (4) ◽  
pp. A2208
Author(s):  
Amnah Andrabi ◽  
Preeyanka Sundar ◽  
Bindu Gandrapu ◽  
Kashif Aslam ◽  
Thomas Fynan
Keyword(s):  
2020 ◽  
Vol 11 (10) ◽  
pp. 1-3
Author(s):  
Shamsudeen Moideen ◽  
Maheshwari V ◽  
Raghuveer Prabhu

Light chain multiple myeloma (LCMM) initiates approximately 15 percentage of patients with multiple myeloma (MM). It has a lower prognosis when compared with the variant immunoglobulin (Ig) G or IgA. We report a rare case on Light chain multiple myeloma in 49-year-old male patient who presented with acute kidney injury, hypercalcemia. histopathology examination was found to be plasmacytoma, kappa restricted; and free kappa lamda chain in urine and serum was found to be greater. Bone pain and renal dysfunction were the most common prevalent initial signs and symptoms while extramedullary disease (EMD) was later acquired during disease. Bortezomib demonstrated superior efficacy over nonbortezomib in LCMM patients.


2021 ◽  
Vol 5 ◽  
pp. AB228-AB228
Author(s):  
Waris Ali Shah ◽  
Zeeshan Razzaq ◽  
Hamid Mustafa ◽  
Sarah Lungley ◽  
Mohammed Daoud ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Prarthna V. Bhardwaj ◽  
Shrinkhala Khanna ◽  
Majd D. Jawad ◽  
Syed S. Ali

Extramedullary myeloma, defined by presence of plasma cells outside the bone marrow, is a rare entity accounting for about 3–9% of all cases. It usually is aggressive with a median survival of <6 months. It is also associated with adverse prognostic factors including 17p deletions and high-risk gene profiles. While common extramedullary sites include bones, there have been several case reports of hematogenous extramedullary myeloma to the liver, lungs, pancreas, breast, skin, and soft tissues. Extramedullary myeloma to the mesentery is a rare entity with only a handful of cases reported. We present a case of 69-year-old man presenting with relapse of multiple myeloma to the mesentery, resulting in bowel obstruction to highlight the various presentations of myeloma.


2017 ◽  
Vol 16 (1) ◽  
pp. 142-145
Author(s):  
Bimal K Agrawal ◽  
Anshul Sehgal ◽  
Vikas Deswal ◽  
Prem Singh ◽  
Usha Agrawal

Multiple myeloma is a neoplasm of plasma cells in the bone marrow. It is characterised by lytic lesions in the bones, marrow plasmacytosis and presence of M protein in serum and/or urine. Serum ?2 microglobulin is also raised and can be used for classification and prognostication of the disease. In the absence of M protein, the disease is known as non-secretory myeloma. It is proposed that raised ?2 microglobulin can be used for diagnosis and therapeutic guidance in the absence of M protein. A rare case of nonsecretory myeloma with neurocognitive impairment along with review of literature is being presented. The patient had multiple lytic lesions in bones with marked increase in plasma cells in bone marrow. M protein was not detectable in serum or urine but serum ?2 microglobulin was much elevated.Bangladesh Journal of Medical Science Vol.16(1) 2017 p.142-145


2017 ◽  
Vol 21 (1) ◽  
Author(s):  
Swati Singh ◽  
Vaishali Upadhyaya ◽  
Rajat Agarwal ◽  
Ratni B. Gujral

Solitary plasmacytoma of bone without signs of multiple myeloma is a rare entity. It usually presents as an osteolytic lesion in the axial skeleton of an elderly patient. Here, we report a case of solitary plasmacytoma in the skull of a young male patient which emphasises the need to consider it in the differential diagnosis of a destructive calvarial mass lesion even in this age group.


2018 ◽  
Vol 2018 ◽  
pp. 1-5
Author(s):  
A. Raissi ◽  
Z. Chahbi ◽  
M. Zyani ◽  
Y. Darouassi

Multiple myeloma is a plasma cell dyscrasis characterized by mature B cells proliferation in the bone marrow. In rare cases, the disease can present as an extramedullary location, making diagnosis and management more challenging. Here, we describe a rare case of tongue extramedullary myeloma and discuss diagnostic, prognostic, and therapeutic issues.


2012 ◽  
Vol 10 (4) ◽  
pp. 498-501 ◽  
Author(s):  
Juliana Todaro ◽  
Patrícia Weinschenker Bollmann ◽  
Amit Nussbacher ◽  
Luis Fernando Aranha Camargo ◽  
Bento Fortunato Cardoso dos Santos ◽  
...  

Patients diagnosed with multiple myeloma are more susceptible to infections which are the major causes of morbidity and mortality associated to this disease. The main infectious agents involved are Gram-positive bacteria. However, after chemotherapy an increase in the incidence of Gram-negative strains is observed. These bacteria are also responsible for most cases of urinary tract infections. Here is reported a rare case in a 73-year-old man with multiple myeloma who developed endocarditis due to pseudomonas.


CHEST Journal ◽  
2019 ◽  
Vol 156 (4) ◽  
pp. A1851-A1852
Author(s):  
Andrew Boulos ◽  
Joshiah Gordon ◽  
Megan Reichmuth ◽  
Paul McCarthy
Keyword(s):  

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