Enhancing the detection sensitivity of trace analysis of pharmaceutical genotoxic impurities by chemical derivatization and coordination ion spray-mass spectrometry

2010 ◽  
Vol 1217 (3) ◽  
pp. 302-306 ◽  
Author(s):  
Lin Bai ◽  
Mingjiang Sun ◽  
Jianguo An ◽  
David Q. Liu ◽  
Ted K. Chen ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Trace Analysis ◽  
Detection Sensitivity ◽  
Chemical Derivatization ◽  
Genotoxic Impurities ◽  
Ion Spray Mass Spectrometry

Mass Spectrometry for Trace Analysis of Explosives in Water

2012 ◽  
Vol 42 (3) ◽  
pp. 257-271 ◽  
Author(s):  
Koffi Badjagbo ◽  
Sébastien Sauvé
Keyword(s):  
Mass Spectrometry ◽  
Trace Analysis

scholarly journals High yield accelerated reactions in nonvolatile microthin films: chemical derivatization for analysis of single-cell intracellular fluid

2018 ◽  
Vol 9 (40) ◽  
pp. 7779-7786 ◽  
Author(s):  
Zhenwei Wei ◽  
Xiaochao Zhang ◽  
Jinyu Wang ◽  
Sichun Zhang ◽  
Xinrong Zhang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Single Cell ◽  
Individual Cell ◽  
High Yield ◽  
Chemical Derivatization ◽  
Intracellular Fluid ◽  
Mild Conditions ◽  
Successful Analysis ◽  
Trace Components

The identification of trace components from an individual cell can require derivatization under mild conditions for successful analysis by mass spectrometry (MS).

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