Extraction optimization of accelerated solvent extraction for eight active compounds from Yaobitong capsule using response surface methodology: Comparison with ultrasonic and reflux extraction

2020 ◽  
Vol 1620 ◽  
pp. 460984
Author(s):  
Yinghe Ji ◽  
Xianhui Li ◽  
Zhenzhong Wang ◽  
Wei Xiao ◽  
Zhonggui He ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Solvent Extraction ◽  
Response Surface ◽  
Accelerated Solvent Extraction ◽  
Active Compounds ◽  
Extraction Optimization

scholarly journals Accelerated solvent extraction of bioactive compounds from carrot: Optimization of response surface methodology

2018 ◽  
Vol 83 (11) ◽  
pp. 1223-1228 ◽  
Author(s):  
Vanja Seregelj ◽  
Vesna Tumbas-Saponjac ◽  
Anamarija Mandic ◽  
Gordana Cetkovic ◽  
Jasna Canadanovic-Brunet ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Solvent Extraction ◽  
Response Surface ◽  
Bioactive Compounds ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Accelerated Solvent Extraction ◽  
Carotenoid Content ◽  
Extraction Temperature ◽  
Significant Difference

Carrot is considered to be rich in bioactive antioxidants, both lipophilic (carotenoids) and hydrophilic (phenolic compounds). In the present study, the conditions for accelerated solvent extraction (ASE) of bioactive compounds from carrots (Daucus carota L.) were optimized using response surface methodology (RSM). Box?Behnken design was employed for the experimental design to obtain the optimized combination of extraction temperature, time, and number of extraction cycles. Total carotenoid content (TCar), total polyphenol content (TPh), free radical scavenging activity (SA) and reducing power (RP) of the obtained extracts were used as responses for the optimization. Considering the four quality indicators, the ideal extraction conditions were found to be: 120 ?C, 60 min and three extraction cycles. Under these conditions, predicted values of 28.84 mg ?-carotene/100 g for TCar; 530.81 mg GAE/100 g for TPh; 2572.29 ?mol TE/100 g for SA and 1336.26 ?mol TE/100 g for RP were obtained with high desirability (0.975) and no significant difference (p < 0.05) with the experimental values.

Optimization of continuous air-assisted solvent extraction for treating dilute Cu leach solutions using response surface methodology

2019 ◽  
Vol 131 ◽  
pp. 154-163 ◽  
Author(s):  
Soroush Rahmati ◽  
Ali Ahmadi ◽  
Mohammad Raouf Hosseini ◽  
Mehdi Molaei Nasab
Keyword(s):  
Response Surface Methodology ◽  
Solvent Extraction ◽  
Response Surface
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