Minimising instilled volume reduces the impact of fluorescein on clinical measurements of tear film stability

2017 ◽  
Vol 40 (3) ◽  
pp. 170-174 ◽  
Author(s):  
Jennifer K. Mooi ◽  
Michael T.M. Wang ◽  
Joevy Lim ◽  
Andreas Müller ◽  
Jennifer P. Craig
Keyword(s):  
Tear Film ◽  
Film Stability ◽  
Tear Film Stability ◽  
Clinical Measurements ◽  
The Impact

scholarly journals Effect of ocular demodicosis on the stability of the tear film and the tear break up time

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Aleksandra Sędzikowska ◽  
Witold Tarkowski ◽  
Joanna Moneta-Wielgoś ◽  
Krzysztof Grzyliński ◽  
Grzegorz Tarkowski ◽  
...  
Keyword(s):  
Tear Film ◽  
Hair Follicles ◽  
Film Stability ◽  
Mean Values ◽  
Non Invasive ◽  
Tear Film Stability ◽  
Break Up ◽  
The Difference ◽  
The Stability ◽  
The Impact

AbstractThe aim of the study was to analyze the correlation between the presence of Demodex mites in the hair follicles of patients' eyelashes and the stability and break up time of the tear film assessed with the Non-Invasive Tear Break Up Times (NIBUT) method. 319 patients were included in the study (195 women, 124 men). The patients were divided into two groups: those with Demodex infestation and without visible symptoms of eyelid or eye surface diseases, and asymptomatic non-infested patients. The NIBUT analysis was performed with a 5 M keratograph (oculus). Non-invasive tests were performed to identify the first and mean values of the tear break up time. The first and mean tear break up time in the Demodex-infested group was lower than in the non-infested subjects. The difference was a highly statistically significant. There was a significant correlation with the age of the patients for the first break up time. The first break up time in both eyes decreased with the age of the Demodex-infested and non-infested patients. The NIBUT analyses indicate the impact of Demodex mites on the tear film stability. This may suggest possible association of demodicosis with dry eye syndrome.

scholarly journals Clinical and biochemical analysis of the ageing tear film

2019 ◽  
Vol 104 (7) ◽  
pp. 1028-1032 ◽  
Author(s):  
Aisling Mann ◽  
Darren Campbell ◽  
Zeba Mirza ◽  
Olivia Hunt ◽  
James Stuart Wolffsohn ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Age Groups ◽  
Tear Film ◽  
Physical Parameters ◽  
Film Stability ◽  
Clinical Investigations ◽  
Tear Film Stability ◽  
Group A ◽  
Tear Meniscus Height ◽  
Clinical Measurements

BackgroundTear film stability is important for healthy visual function, and yet little is known of the ageing mechanisms. The aim of this study was to investigate parallels between biochemical changes and clinical physical parameters, which occur in the tear film of two subject populations differing in age by over 30 years.MethodsTwo distinct age groups were chosen: 11 ‘younger’ (23.7±2.1 years) and 19 ‘older’ (63.0±4.0 years) subjects. A series of clinical tests were performed to access tear volume, tear film stability and general ocular health. Tear protein analyses from extracted Schirmer strips were conducted with the Agilent 2100 Bioanalyzer.ResultsClinical investigations highlighted significant differences between the age groups. For example: McMonnies scores (p=0.009) and bulbar redness (p=0.038) were higher for the older group, whereas tear meniscus height was larger (p=0.018) in the younger group. Similarly, relative plasma-derived albumin levels were higher (17.1%±12.4%) in the tears of the older, compared with the younger (5.0%±9.6%) group. A protein peak at ∼23 kDa was observed in 53% of the older group samples but in only 36% of the samples of the younger subjects (p=0.122).ConclusionsDistinct differences in tear film composition between the two age groups were observed. Parallels in terms of clinical symptoms which reflected a biochemical response (and vice versa) were found, but specific correlations between clinical measurements and biomarkers for individual subjects were not observed.

scholarly journals A single-center study evaluating the effect of the controlled adverse environment (CAEsm) model on tear film stability

2012 ◽  
pp. 1865 ◽  
Author(s):  
Richard Abelson ◽  
Keith Lane ◽  
John Rodriguez ◽  
Patrick Johnston ◽  
Angjeli ◽  
...  
Keyword(s):  
Tear Film ◽  
Single Center ◽  
Film Stability ◽  
Single Center Study ◽  
Tear Film Stability ◽  
Center Study

Associations between dry eye symptoms with tear film stability, volume, and osmolarity in a sample of young adults in Kuala Lumpur

2018 ◽  
Vol 10 (1) ◽  
pp. 32
Author(s):  
Bariah Mohd-Ali ◽  
MohamadHanif Hajar-Maidin ◽  
Asmah Ahmad ◽  
Zainora Mohammed ◽  
Jamaluddin Mohamed
Keyword(s):  
Young Adults ◽  
Dry Eye ◽  
Tear Film ◽  
Kuala Lumpur ◽  
Film Stability ◽  
Tear Film Stability ◽  
Eye Symptoms ◽  
Dry Eye Symptoms
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