This chapter discusses clinical applications of spontaneous EEG and MEG as well as evoked responses in epileptic and stroke patients, and in presurgical mapping (including identification of the central sulcus). EEG and MEG remain, due to their excellent temporal resolution, the methods par excellence for diagnosing and identifying epileptic syndromes. Timing of discharges can differentiate primary and secondary (mirror) epileptic foci. In contrast to studies of clinical populations for research purposes, clinical assessment is always based on findings in individual subjects, and the tests thus have to be reliable with high specificity and high sensitivity, showing statistically significant differences compared with normative values of healthy subjects with similar attributes, including age. The chapter ends by discussing EEG monitoring in coma or brain death.
Rogue bioelectrical waves in the brain: the Hurst exponent as a potential measure for presurgical mapping in epilepsy
