scholarly journals Evaluation of a molecular point-of-care testing for viral and atypical pathogens on intravenous antibiotic duration in hospitalized adults with lower respiratory tract infection: a randomized clinical trial

2019 ◽  
Vol 25 (11) ◽  
pp. 1415-1421 ◽  
Author(s):  
D. Shengchen ◽  
X. Gu ◽  
G. Fan ◽  
R. Sun ◽  
Y. Wang ◽  
...  
2018 ◽  
Vol 28 (5) ◽  
pp. e1995 ◽  
Author(s):  
Ece Egilmezer ◽  
Gregory J. Walker ◽  
Padmavathy Bakthavathsalam ◽  
Joshua R. Peterson ◽  
J. Justin Gooding ◽  
...  

BMJ Open ◽  
2018 ◽  
Vol 8 (10) ◽  
pp. e024558 ◽  
Author(s):  
Matthew Johnson ◽  
Liz Cross ◽  
Nick Sandison ◽  
Jamie Stevenson ◽  
Thomas Monks ◽  
...  

ObjectivesUtilisation of point-of-care C-reactive protein testing for lower respiratory tract infection has been limited in UK primary care, with costs and funding suggested as important barriers. We aimed to use existing National Health Service funding and policy mechanisms to alleviate these barriers and engage with clinicians and healthcare commissioners to encourage implementation.DesignA mixed-methods study design was adopted, including a qualitative survey to identify clinicians’ and commissioners’ perceived benefits, barriers and enablers post-implementation, and quantitative analysis of results from a real-world implementation study.InterventionsWe developed a funding specification to underpin local reimbursement of general practices for test delivery based on an item of service payment. We also created training and administrative materials to facilitate implementation by reducing organisational burden. The implementation study provided intervention sites with a testing device and supplies, training and practical assistance.ResultsDespite engagement with several groups, implementation and uptake of our funding specification were limited. Survey respondents confirmed costs and funding as important barriers in addition to physical and operational constraints and cited training and the value of a local champion as enablers.ConclusionsAlthough survey respondents highlighted the clinical benefits, funding remains a barrier to implementation in UK primary care and appears not to be alleviated by the existing financial incentives available to commissioners. The potential to meet incentive targets using lower cost methods, a lack of policy consistency or competing financial pressures and commissioning programmes may be important determinants of local priorities. An implementation champion could help to catalyse support and overcome operational barriers at the local level, but widespread implementation is likely to require national policy change. Successful implementation may reproduce antibiotic prescribing reductions observed in research studies.


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