Design of nanoporous titania-supported methylene blue molecules for efficient singlet oxygen generation under red light exposure

2019 ◽  
Vol 30 ◽  
pp. 100185
Author(s):  
Iori Yamada ◽  
Ryota Ikeda ◽  
Shinya Nagata ◽  
Masaya Kakuta ◽  
Motohiro Tagaya
2013 ◽  
Vol 48 (7) ◽  
pp. 2636-2639 ◽  
Author(s):  
M. Wojtoniszak ◽  
D. Rogińska ◽  
B. Machaliński ◽  
M. Drozdzik ◽  
E. Mijowska

2017 ◽  
Vol 114 (28) ◽  
pp. 7278-7282 ◽  
Author(s):  
Patrick L. Donabedian ◽  
Matthew N. Creyer ◽  
Florencia A. Monge ◽  
Kirk S. Schanze ◽  
Eva Y. Chi ◽  
...  

Photodynamic therapy, in which malignant tissue is killed by targeted light exposure following administration of a photosensitizer, can be a valuable treatment modality but currently relies on passive transport and local irradiation to avoid off-target oxidation. We present a system of excited-state control for truly local delivery of singlet oxygen. An anionic phenylene ethynylene oligomer is initially quenched by water, producing minimal fluorescence and no measurable singlet oxygen generation. When presented with a binding partner, in this case an oppositely charged surfactant, changes in solvent microenvironment result in fluorescence unquenching, restoration of intersystem crossing to the triplet state, and singlet oxygen generation, as assayed by transient absorption spectroscopy and chemical trapping. This solvation-controlled photosensitizer model has possible applications as a theranostic agent for, for example, amyloid diseases.


RSC Advances ◽  
2020 ◽  
Vol 10 (21) ◽  
pp. 12304-12307
Author(s):  
Xiaomu Xu ◽  
Yusheng Hu ◽  
Li-peng Zhang ◽  
Bo Liu ◽  
Yue Yang ◽  
...  

Enhanced antibacterial effect of MPNPs through increased singlet oxygen generation as a result of decreased ACQ effect


2006 ◽  
Vol 91 (4) ◽  
pp. 1452-1459 ◽  
Author(s):  
Jürgen Baier ◽  
Tim Maisch ◽  
Max Maier ◽  
Eva Engel ◽  
Michael Landthaler ◽  
...  

2021 ◽  
Author(s):  
Esra Tanrıverdi Eçik ◽  
Onur BULUT ◽  
Hasan Hüseyin Kazan ◽  
Elif Şenkuytu ◽  
Bunyemin Cosut

Photodynamic therapy (PDT) is a promising strategy in cancer treatment with its relatively lower side effect profile. Undoubtedly, the key component of PDT is the photosensitizers with a high ability...


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