Complementary effect of Zingiber officinalis extract and citral in counteracting non allergic nasal congestion by simultaneous loading in ad hoc formulated phospholipid vesicles

2021 ◽  
pp. 112170
Author(s):  
Eleonora Casula ◽  
Maria Manconi ◽  
Tania Belen Lopez-Mendez ◽  
Jose Luis Pedraz ◽  
Esteban Calvo ◽  
...  
Keyword(s):  
Ad Hoc ◽  
Nasal Congestion ◽  
Phospholipid Vesicles ◽  
Complementary Effect ◽  
Simultaneous Loading

scholarly journals Extraction, Characterization and Incorporation of Hypericum scruglii Extract in Ad Hoc Formulated Phospholipid Vesicles Designed for the Treatment of Skin Diseases Connected with Oxidative Stress

Pharmaceutics ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 1010
Author(s):  
Mohamad Allaw ◽  
Maria Manconi ◽  
Matteo Aroffu ◽  
Francesca Marongiu ◽  
Marco Porceddu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ad Hoc ◽  
Skin Diseases ◽  
Phospholipid Vesicles ◽  
Endemic Plant ◽  
Skin Delivery ◽  
Scratch Wound ◽  
Physicochemical Features ◽  
And Migration

An extract of Hypericum scruglii, an endangered endemic plant of Sardinia (Italy), was prepared and characterized. It was loaded in special phospholipid vesicles, glycerosomes, which were modified by adding maltodextrin (glucidex) and a polymer (gelatin or hyaluronan). The corresponding liposomes were also prepared and used as reference. The vesicles disclosed suitable physicochemical features for skin delivery. Indeed, their mean diameter ranged from 120 to 160 nm, they were homogeneously dispersed (polydispersity index ≤ 0.30), and their zeta potential was highly negative (~−45 mV). The vesicle dispersions maintained unchanged characteristics during 60 days of storage, were highly biocompatible, and were able to protect keratinocytes against damages due to oxidative stress induced by treating them with hydrogen peroxide. Vesicles were also capable of promoting cell proliferation and migration in vitro by means of a scratch wound assay. The results confirmed the fruitful delivery of the extract of H. scruglii in glycerosomes modified with glucidex and gelatin and their promising ability for skin protection and treatment.

Die COVID-19-Pandemie im akutstationären Setting aus Sicht von Führungspersonen und Hygienefachkräften in der Pflege

Pflege ◽  
2020 ◽  
Vol 33 (5) ◽  
pp. 289-298
Author(s):  
Katharina Silies ◽  
Angelika Schley ◽  
Janna Sill ◽  
Steffen Fleischer ◽  
Martin Müller ◽  
...  
Keyword(s):  
Ad Hoc ◽  
Qualitative Studie ◽  
Skill Mix ◽  
Task Forces

Zusammenfassung. Hintergrund: Die COVID-19-Pandemie ist eine Ausnahmesituation ohne Präzedenz und erforderte zahlreiche Ad-hoc-Anpassungen in den Strukturen und Prozessen der akutstationären Versorgung. Ziel: Ziel war es zu untersuchen, wie aus Sicht von Führungspersonen und Hygienefachkräften in der Pflege die stationäre Akutversorgung durch die Pandemiesituation beeinflusst wurde und welche Implikationen sich daraus für die Zukunft ergeben. Methoden: Qualitative Studie bestehend aus semistrukturierten Interviews mit fünf Verantwortlichen des leitenden Pflegemanagements und drei Hygienefachkräften in vier Krankenhäusern in Deutschland. Die Interviews wurden mittels qualitativer Inhaltsanalyse ausgewertet. Ergebnisse: Die Befragten beschrieben den auf die prioritäre Versorgung von COVID-19-Fällen hin umstrukturierten Klinikalltag. Herausforderungen waren Unsicherheit und Angst bei den Mitarbeiter_innen, relative Ressourcenknappheit von Material und Personal und die schnelle Umsetzung neuer Anforderungen an die Versorgungleistung. Dem wurde durch gezielte Kommunikation und Information, massive Anstrengungen zur Sicherung der Ressourcen und koordinierte Steuerung aller Prozesse durch bereichsübergreifende, interprofessionelle Task Forces begegnet. Schlussfolgerungen: Die in der COVID-19-Pandemie vorgenommenen Anpassungen zeigen Entwicklungspotenziale für die zukünftige Routineversorgung auf, z. B. könnten neue Arbeits- und Skill Mix-Modelle aufgegriffen werden. Für die Konkretisierung praktischer Implikationen sind vertiefende Analysen der Daten mit zeitlichem Abstand erforderlich.

Tests und Tools

2006 ◽  
Vol 5 (2) ◽  
pp. 68-71 ◽  
Author(s):  
Simone Kauffeld
Keyword(s):  
Ad Hoc ◽  
Non Profit

Zusammenfassung. Der FEO, der in Kooperation mit betrieblichen Praktikern entwickelt wurde, dient der Erfassung des Organisationsklimas. Er umfasst 82 Items und bildet 12 Skalen ab. Eine Stärke des FEO im Gegensatz zu ad hoc entwickelten Befragungsinstrumenten sind die Vergleichsdaten, die für Profit- und Non-Profit-Organisationen bereit gestellt werden. Kritisch diskutiert wird die theoretische Verortung, die Anwenderfreundlichkeit sowie der Nutzen der individuellen Auswertung. Die konsensuale, konvergente, diskriminante und kriterienbezogene Validierung steht aus.

Test Use in Spain, Portugal and Latin American Countries

1999 ◽  
Vol 15 (2) ◽  
pp. 151-157 ◽  
Author(s):  
José Muñiz ◽  
Gerardo Prieto ◽  
Leandro Almeida ◽  
Dave Bartram
Keyword(s):  
Latin American ◽  
Ad Hoc ◽  
Task Force ◽  
Test Construction ◽  
European Federation ◽  
Psychometric Characteristics ◽  
Testing Practices ◽  
Professional Psychologists ◽  
Test Use ◽  
Latin American Countries

Summary: The two main sources of errors in educational and psychological evaluation are the lack of adequate technical and psychometric characteristics of the tests, and especially the failure to properly implement the testing process. The main goal of the present research is to study the situation of test construction and test use in the Spanish-speaking (Spain and Latin American countries) and Portuguese-speaking (Portugal and Brazil) countries. The data were collected using a questionnaire constructed by the European Federation of Professional Psychologists Association (EFPPA) Task Force on Tests and Testing, under the direction of D. Bartram . In addition to the questionnaire, other ad hoc data were also gathered. Four main areas of psychological testing were investigated: Educational, Clinical, Forensic and Work. Key persons were identified in each country in order to provide reliable information. The main results are presented, and some measures that could be taken in order to improve the current testing practices in the countries surveyed are discussed. As most of the tests used in these countries were originally developed in other cultures, a problem that appears to be especially relevant is the translation and adaptation of tests.

Acknowledgment of ad hoc reviewers, 2002.

2002 ◽  
Vol 33 (6) ◽  
pp. 596-596
Author(s):  
No authorship indicated
Keyword(s):  
Ad Hoc
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