scholarly journals Unified Focal loss: Generalising Dice and cross entropy-based losses to handle class imbalanced medical image segmentation

Author(s):  
Michael Yeung ◽  
Evis Sala ◽  
Carola-Bibiane Schönlieb ◽  
Leonardo Rundo
Author(s):  
Zhenzhen Yang ◽  
Pengfei Xu ◽  
Yongpeng Yang ◽  
Bing-Kun Bao

The U-Net has become the most popular structure in medical image segmentation in recent years. Although its performance for medical image segmentation is outstanding, a large number of experiments demonstrate that the classical U-Net network architecture seems to be insufficient when the size of segmentation targets changes and the imbalance happens between target and background in different forms of segmentation. To improve the U-Net network architecture, we develop a new architecture named densely connected U-Net (DenseUNet) network in this article. The proposed DenseUNet network adopts a dense block to improve the feature extraction capability and employs a multi-feature fuse block fusing feature maps of different levels to increase the accuracy of feature extraction. In addition, in view of the advantages of the cross entropy and the dice loss functions, a new loss function for the DenseUNet network is proposed to deal with the imbalance between target and background. Finally, we test the proposed DenseUNet network and compared it with the multi-resolutional U-Net (MultiResUNet) and the classic U-Net networks on three different datasets. The experimental results show that the DenseUNet network has significantly performances compared with the MultiResUNet and the classic U-Net networks.


Entropy ◽  
2020 ◽  
Vol 22 (8) ◽  
pp. 844
Author(s):  
Baixin Jin ◽  
Pingping Liu ◽  
Peng Wang ◽  
Lida Shi ◽  
Jing Zhao

Medical image segmentation is an important part of medical image analysis. With the rapid development of convolutional neural networks in image processing, deep learning methods have achieved great success in the field of medical image processing. Deep learning is also used in the field of auxiliary diagnosis of glaucoma, and the effective segmentation of the optic disc area plays an important assistant role in the diagnosis of doctors in the clinical diagnosis of glaucoma. Previously, many U-Net-based optic disc segmentation methods have been proposed. However, the channel dependence of different levels of features is ignored. The performance of fundus image segmentation in small areas is not satisfactory. In this paper, we propose a new aggregation channel attention network to make full use of the influence of context information on semantic segmentation. Different from the existing attention mechanism, we exploit channel dependencies and integrate information of different scales into the attention mechanism. At the same time, we improved the basic classification framework based on cross entropy, combined the dice coefficient and cross entropy, and balanced the contribution of dice coefficients and cross entropy loss to the segmentation task, which enhanced the performance of the network in small area segmentation. The network retains more image features, restores the significant features more accurately, and further improves the segmentation performance of medical images. We apply it to the fundus optic disc segmentation task. We demonstrate the segmentation performance of the model on the Messidor dataset and the RIM-ONE dataset, and evaluate the proposed architecture. Experimental results show that our network architecture improves the prediction performance of the base architectures under different datasets while maintaining the computational efficiency. The results render that the proposed technologies improve the segmentation with 0.0469 overlapping error on Messidor.


2019 ◽  
Vol 31 (6) ◽  
pp. 1007 ◽  
Author(s):  
Haiou Wang ◽  
Hui Liu ◽  
Qiang Guo ◽  
Kai Deng ◽  
Caiming Zhang

Electronics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 348
Author(s):  
Choongsang Cho ◽  
Young Han Lee ◽  
Jongyoul Park ◽  
Sangkeun Lee

Semantic image segmentation has a wide range of applications. When it comes to medical image segmentation, its accuracy is even more important than those of other areas because the performance gives useful information directly applicable to disease diagnosis, surgical planning, and history monitoring. The state-of-the-art models in medical image segmentation are variants of encoder-decoder architecture, which is called U-Net. To effectively reflect the spatial features in feature maps in encoder-decoder architecture, we propose a spatially adaptive weighting scheme for medical image segmentation. Specifically, the spatial feature is estimated from the feature maps, and the learned weighting parameters are obtained from the computed map, since segmentation results are predicted from the feature map through a convolutional layer. Especially in the proposed networks, the convolutional block for extracting the feature map is replaced with the widely used convolutional frameworks: VGG, ResNet, and Bottleneck Resent structures. In addition, a bilinear up-sampling method replaces the up-convolutional layer to increase the resolution of the feature map. For the performance evaluation of the proposed architecture, we used three data sets covering different medical imaging modalities. Experimental results show that the network with the proposed self-spatial adaptive weighting block based on the ResNet framework gave the highest IoU and DICE scores in the three tasks compared to other methods. In particular, the segmentation network combining the proposed self-spatially adaptive block and ResNet framework recorded the highest 3.01% and 2.89% improvements in IoU and DICE scores, respectively, in the Nerve data set. Therefore, we believe that the proposed scheme can be a useful tool for image segmentation tasks based on the encoder-decoder architecture.


2021 ◽  
Author(s):  
Dachuan Shi ◽  
Ruiyang Liu ◽  
Linmi Tao ◽  
Zuoxiang He ◽  
Li Huo

2021 ◽  
pp. 1-19
Author(s):  
Maria Tamoor ◽  
Irfan Younas

Medical image segmentation is a key step to assist diagnosis of several diseases, and accuracy of a segmentation method is important for further treatments of different diseases. Different medical imaging modalities have different challenges such as intensity inhomogeneity, noise, low contrast, and ill-defined boundaries, which make automated segmentation a difficult task. To handle these issues, we propose a new fully automated method for medical image segmentation, which utilizes the advantages of thresholding and an active contour model. In this study, a Harris Hawks optimizer is applied to determine the optimal thresholding value, which is used to obtain the initial contour for segmentation. The obtained contour is further refined by using a spatially varying Gaussian kernel in the active contour model. The proposed method is then validated using a standard skin dataset (ISBI 2016), which consists of variable-sized lesions and different challenging artifacts, and a standard cardiac magnetic resonance dataset (ACDC, MICCAI 2017) with a wide spectrum of normal hearts, congenital heart diseases, and cardiac dysfunction. Experimental results show that the proposed method can effectively segment the region of interest and produce superior segmentation results for skin (overall Dice Score 0.90) and cardiac dataset (overall Dice Score 0.93), as compared to other state-of-the-art algorithms.


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