scholarly journals Cortisol in relation to problematic eating behaviours, adiposity and symptom profiles in Major Depressive Disorder

Author(s):  
Jessica G. Mills ◽  
Theresa A. Larkin ◽  
Chao Deng ◽  
Susan J. Thomas
2018 ◽  
Vol 240 ◽  
pp. 137-145 ◽  
Author(s):  
Jessica G. Mills ◽  
Susan J. Thomas ◽  
Theresa A. Larkin ◽  
Nagesh B. Pai ◽  
Chao Deng

2008 ◽  
Vol 192 (5) ◽  
pp. 388-389 ◽  
Author(s):  
Liz Forty ◽  
Daniel Smith ◽  
Lisa Jones ◽  
Ian Jones ◽  
Sian Caesar ◽  
...  

SummaryIt is commonly – but wrongly – assumed that there are no important differences between the clinical presentations of major depressive disorder and bipolar depression. Here we compare clinical course variables and depressive symptom profiles in a large sample of individuals with major depressive disorder (n=593) and bipolar disorder (n=443). Clinical characteristics associated with a bipolar course included the presence of psychosis, diurnal mood variation and hypersomnia during depressive episodes, and a greater number of shorter depressive episodes. Such features should alert a clinician to a possible bipolar course. This is important because optimal management is not the same for bipolar and unipolar depression.


Cephalalgia ◽  
2010 ◽  
Vol 30 (9) ◽  
pp. 1073-1081 ◽  
Author(s):  
Lannie Ligthart ◽  
Brenda WJH Penninx ◽  
Dale R Nyholt ◽  
Marijn A Distel ◽  
Eco JC de Geus ◽  
...  

Introduction and objective: Migraine and major depressive disorder (MDD) frequently co-occur, but it is unclear whether depression is associated with a specific subtype of migraine. The objective of this study was to investigate whether migraine is qualitatively different in MDD patients ( N = 1816) and non-depressed controls ( N = 3428). Methods: Migraine symptom data were analyzed using multi-group Latent Class Analysis, and a qualitative comparison was made between the symptom profiles of MDD patients and controls, while allowing for differences in migraine prevalence and severity between groups. Results: In both groups, three migrainous headache classes were identified, which differed primarily in terms of severity. Both mild and severe migrainous headaches were two to three times more prevalent in MDD patients. Migraine symptom profiles showed only minor qualitative differences in the MDD and non-MDD groups: in the severe migrainous headache class, significant differences were observed only in the prevalence of aggravation by physical activity (83% and 91% for the non-MDD and MDD groups, respectively) and aura (42% vs. 53%, respectively). Conclusion: The similar overall symptom profiles observed in the MDD and non-MDD subjects suggest that a similar disease process may underlie migraine in both groups.


1993 ◽  
Vol 163 (3) ◽  
pp. 374-380 ◽  
Author(s):  
Ian Goodyer ◽  
Peter J. Cooper

The clinical characteristics of two subsamples of 11–16-year-old girls were determined from direct interview: those who met DSM-III-R criteria for an episode of major depressive disorder within the past month (n = 28); and those who did not currently meet these criteria but had done so at some time in the previous 12 months (n = 13). The symptom profiles of these cases were compared with a subsample of girls who reported depressive symptoms but did not meet DSM-III-R criteria and were designated as having a ‘partial syndrome’ (n = 93), and a sample of non-depressed controls (n = 129). Phobias and worry about peer acceptance were common in controls suggesting that these symptoms constitute normal adolescent concerns. The symptom profile of depressed cases altered across three age bands (11–12, 13–14, and 15–16 years), suggesting developmental influences on clinical presentation. Comorbidity for anxiety, behavioural, and obsessional disorders was found in 40% of the depressed cases. None of the cases of major depressive disorder was known to the clinical services.


Sign in / Sign up

Export Citation Format

Share Document