Preservation of microelastic properties of dentin and tooth enamel in vitro—A scanning acoustic microscopy study

2007 ◽  
Vol 23 (10) ◽  
pp. 1221-1228 ◽  
Author(s):  
K RAUM ◽  
K KEMPF ◽  
H HEIN ◽  
J SCHUBERT ◽  
P MAURER
1999 ◽  
Vol 103 (1-3) ◽  
pp. 2439-2442 ◽  
Author(s):  
V.M. Prokhorov ◽  
V.D. Blank ◽  
S.G. Buga ◽  
V.M. Levin

1994 ◽  
Vol 29 (3) ◽  
pp. 231-240 ◽  
Author(s):  
P. Veselý ◽  
H. Lüers ◽  
M. Riehle ◽  
J. Bereiter-Hahn

2014 ◽  
Vol 55 (3) ◽  
pp. 1549 ◽  
Author(s):  
Ithar M. Beshtawi ◽  
Riaz Akhtar ◽  
M. Chantal Hillarby ◽  
Clare O'Donnell ◽  
Xuegen Zhao ◽  
...  

Author(s):  
Gustav Ofosu

Platinum-thymine has been found to be a potent antitumor agent, which is quite soluble in water, and lack nephrotoxicity as the dose-limiting factor. The drug has been shown to interact with DNA and inhibits DNA, RNA and protein synthesis in mammalian cells in vitro. This investigation was undertaken to elucidate the cytotoxic effects of piatinum-thymine on sarcoma-180 cells in vitro ultrastructurally, Sarcoma-180 tumor bearing mice were treated with intraperitoneal injection of platinum-thymine 40mg/kg. A concentration of 60μg/ml dose of platinum-thymine was used in in vitro experiments. Treatments were at varying time intervals of 3, 7 and 21 days for in vivo experiments, and 30, 60 and 120 min., 6, 12, and 24th in vitro. Controls were not treated with platinum-thymine.Electron microscopic analyses of the treated cells in vivo and in vitro showed drastic cytotoxic effect.


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